GC-MS Analysis of Polychlorinated Dibenzodioxins and Polychlorinated Dibenzofurans

By: Katherine Stenerson

Courtesy of Sigma-Aldrich/Supelco

Jun. 5, 2012

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Polychlorinated dibenzodioxins (PCDDs) and polychlorinated dibenzofurans (PCDFs) consist of 210 different compounds with varying degrees of toxicity, and the 17 congeners with chlorine substitution in the 2,3,7,8 positions are considered the most toxic. This chromatogram illustrates the separation of a 17 component 2,3,7,8-substituted PCDD and PCDF standard on a 30 m x 0.25 mm I.D. x 0.25 μm SLB-5ms column. Note the resolution between 1,2,3,4,7,8-HxCDD and 1,2,3,6,7,8-HxCDD. US EPA Method 8280, which is for the analysis of these compounds by low resolution GC-MS, requires ≥ 50% resolution between these two isomers.

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RELATED PRODUCT

28471-U - SLB<sup>®</sup>-5ms Capillary GC Column

28471-U - SLB^®-5ms Capillary GC Column

L × I.D. 30 m × 0.25 mm, df 0.25 μm Application: The 5% phenyl equivalent phase provides a boiling point elution order with a slight increase in selectivity, especially for aromatic compounds. The low bleed characteristics, inertness, and durable nature make it the column of choice for environmental analytes (such as semivolatiles, pesticides, PCBs, and herbicides) or anywhere a low bleed non-polar column is required. ...