radiation dose Articles

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Threshold dose problems in radiation carcinogenesis: a review of non-tumour doses

by Inderscience Publishers  (Oct. 4, 2004)

Non-tumour-inducing doses exist in dose-response data on experimental animals and humans, although a linear non-threshold model has been adopted for estimating cancer risk of ionising radiation at a low dose region for radiation protection purposes. Here, data on non- tumour dose, Dnt, the maximum dose at which a statistically significant increase ...

Experimental studies on the biological effects of low-dose-rate and low-dose radiation

by Inderscience Publishers  (Jun. 19, 2008)

A lifespan study using a total of 4000 adult Specific Pathogen-Free (SPF) mice indicated that continuous gamma-ray exposures of both females and males for approximately 400 days at a dose rate of 20 mGy/day induced significant life shortening, mainly due to early neoplastic death, but no significant differences were found after exposure at a dose ...

Clinical significance of low-dose radiation therapy: radiation hormesis

by Inderscience Publishers  (Dec. 27, 2010)

This study was designed to investigate the clinical significance of low-dose radiation therapy, radiation hormesis, and accuracy of therapeutic regimen. Radiation hormesis was performed in six patients (four patients with malignant diseases and two patients with benign diseases) in the experimental room where they could be exposed to a low level ...

Epistemology on the attribution of radiation risks and effects to low radiation dose exposure situations

by Inderscience Publishers  (Apr. 2, 2012)

The epistemology on the attribution of radiation risks and effects relates to the theories of knowledge applied for assigning harm to radiation exposure, especially with regard to methods, validity and scope. The attribution of radiation risk is associated with the concept of probability, including the plausibility of whether there is risk in ...

DNA repair after low doses of ionising radiation

by Inderscience Publishers  (Jan. 10, 2007)

Exposure of mammalian cells to Ionising Radiation (IR) results in an integrated cellular response in which the activation of cell-cycle checkpoints is coordinated with DNA-repair pathways to optimise the removal of potentially cytotoxic or mutagenic DNA lesions. Radiobiological models have usually been based on observations of the cellular ...

Suicides and exposure to low doses of ionising radiation

by Inderscience Publishers  (Nov. 21, 2007)

The suicide rates in southern India are very high (Joseph et al., 2003; Aaron et al., 2004), where there are areas of high natural radiation background (UNSCEAR, 2000). It was a stable tendency towards excess of suicides among the atomic bomb survivors exposed to low doses (0?90 mGy) (Kusumi et al., 1993). It was informed about the direct ...

Low-dose radiation risk and the linear no-threshold model

by Inderscience Publishers  (Sep. 21, 2009)

The Linear No-Threshold (LNT) model has been traditionally used in the field of radiation safety. Public attention to and debate on this model increased after estimates that current Computed Tomography (CT) procedures in the USA will ultimately be responsible for up to 2% of cancers. However, there is evidence that in the mGy range, low doses not ...

Ionising Radiation

by European Environment Agency (EEA)  (Jan. 1, 1996)

Introduction The energy level of some types of radiation is high enough so that when they interact with matter they cause the formation of electrically charged particles or ion-pairs and break molecular bonds. These so-called ionising radiations are by their nature potentially harmful to life; at high doses they can be lethal and at lower doses ...

Low-dose ionising radiation effects: effects of thoron inhalation

by Inderscience Publishers  (Jul. 15, 2014)

Cellular DNA damage, tissue antioxidant levels, serum parameters, blood count and histopathological alterations were examined in tissues of mice exposed to thoron (average radiation dose0.065 μSv/hr). Alkaline cometassay results indicated that inhalation of thoron caused significant increase in the damage to DNA of lung tissue, while there was no ...

The lack of acute effect of low–to–moderate–dose ionising radiation on endothelial proteome

by Inderscience Publishers  (Aug. 1, 2013)

Epidemiological studies have shown that moderate and low radiation doses to the heart area may result in an increase in cardiovascular mortality. It has been suggested that cardiovascular endothelium could be one of the targets for the ionising radiation–induced heart injury. We have used human endothelial cells as an in vitro model to study ...

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