radiation dose Articles

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Threshold dose problems in radiation carcinogenesis: a review of non-tumour doses

by Inderscience Publishers  (Oct. 4, 2004)

Non-tumour-inducing doses exist in dose-response data on experimental animals and humans, although a linear non-threshold model has been adopted for estimating cancer risk of ionising radiation at a low dose region for radiation protection purposes. Here, data on non- tumour dose, Dnt, the maximum dose at which a statistically significant increase ...

Experimental studies on the biological effects of low-dose-rate and low-dose radiation

by Inderscience Publishers  (Jun. 19, 2008)

A lifespan study using a total of 4000 adult Specific Pathogen-Free (SPF) mice indicated that continuous gamma-ray exposures of both females and males for approximately 400 days at a dose rate of 20 mGy/day induced significant life shortening, mainly due to early neoplastic death, but no significant differences were found after exposure at a dose ...

Epistemology on the attribution of radiation risks and effects to low radiation dose exposure situations

by Inderscience Publishers  (Apr. 2, 2012)

The epistemology on the attribution of radiation risks and effects relates to the theories of knowledge applied for assigning harm to radiation exposure, especially with regard to methods, validity and scope. The attribution of radiation risk is associated with the concept of probability, including the plausibility of whether there is risk in ...

Clinical significance of low-dose radiation therapy: radiation hormesis

by Inderscience Publishers  (Dec. 27, 2010)

This study was designed to investigate the clinical significance of low-dose radiation therapy, radiation hormesis, and accuracy of therapeutic regimen. Radiation hormesis was performed in six patients (four patients with malignant diseases and two patients with benign diseases) in the experimental room where they could be exposed to a low level ...

DNA repair after low doses of ionising radiation

by Inderscience Publishers  (Jan. 10, 2007)

Exposure of mammalian cells to Ionising Radiation (IR) results in an integrated cellular response in which the activation of cell-cycle checkpoints is coordinated with DNA-repair pathways to optimise the removal of potentially cytotoxic or mutagenic DNA lesions. Radiobiological models have usually been based on observations of the cellular ...

Low-dose radiation risk and the linear no-threshold model

by Inderscience Publishers  (Sep. 21, 2009)

The Linear No-Threshold (LNT) model has been traditionally used in the field of radiation safety. Public attention to and debate on this model increased after estimates that current Computed Tomography (CT) procedures in the USA will ultimately be responsible for up to 2% of cancers. However, there is evidence that in the mGy range, low doses not ...

Suicides and exposure to low doses of ionising radiation

by Inderscience Publishers  (Nov. 21, 2007)

The suicide rates in southern India are very high (Joseph et al., 2003; Aaron et al., 2004), where there are areas of high natural radiation background (UNSCEAR, 2000). It was a stable tendency towards excess of suicides among the atomic bomb survivors exposed to low doses (0?90 mGy) (Kusumi et al., 1993). It was informed about the direct ...

Ionising Radiation

by European Environment Agency (EEA)  (Jan. 1, 1996)

Introduction The energy level of some types of radiation is high enough so that when they interact with matter they cause the formation of electrically charged particles or ion-pairs and break molecular bonds. These so-called ionising radiations are by their nature potentially harmful to life; at high doses they can be lethal and at lower doses ...

The enhancement of Th1 immunity and the suppression of tumour growth by low-dose γ-radiation

by Inderscience Publishers  (Oct. 30, 2008)

To address if the modulation of immunity balance by low dose radiation is involved in the enhancement of the anti-tumour function, we examined the effect of 0.5 Gy γ-irradiation on the Th1/Th2 immunity balance in Ehrlich Solid Tumour (EST)-bearing mice. Repeated 0.5 Gy γ-irradiation significantly delayed the growth of tumours. The cytotoxic ...

Effects of high dose rate gamma radiation on survival and reproduction of Biomphalaria glabrata

by Inderscience Publishers  (Aug. 31, 2010)

Ionising radiations can cause mutagenesis and death depending on the dose. Based on this, the effects of 60Co gamma radiation at high dose rate on the survival and reproduction of Biomphalaria glabrata, one of the hosts of Schistosoma mansoni, were evaluated in this paper. The results demonstrated lethality in all irradiated groups, despite the ...

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