BÜCHI Labortechnik AG

Chromatography laboratory instrumentation for pharmaceutical industry - Chemical & Pharmaceuticals - Pharmaceutical

Drug discovery and development for pharmaceutical industries require safe, efficient and compliant sample processing and analytics. BUCHI offers a variety of reliable solutions throughout the whole workflow leading to the production of a new drug, from lead generation to the final registration for introduction on the market.

Evaporation & Concentration
Solvent evaporation and sample concentration are pivotal in synthesis, work-up, analytical sample preparation and solvent recycling and pilot scale production. Our highly automated evaporation/concentration solutions cover the complete sample range and allow simple up-scale from lab to production scale.

Purification
“Active Pharmaceutical Ingredients” (APIs) are generated by organic synthesis, biochemical process or extraction. The end result must always be further concentrated and purified. BUCHI chromatography solutions allow the purification of compounds from a few milligrams up to several hundred grams. Our solutions cover the complete sample range and allow simple up-scale from lab to production scale.

Formulation
Formulation of particles, beads or capsules with your active pharmaceutical ingredients, drug delivery, vaccines or inhalable drugs can easily be done with the equipment from BUCHI. If you want to simply dry a sample or protect your target materials with further controlled or target release, we have the solution that covers all your needs.

Incoming inspection & QC
Inspection of the incoming goods and final quality control are prerequisites for ensuring desired quality of your products. Several technologies can be used to achieve these goals:

  • Convenient use of multi-bundle fiber NIR optic probes offer reliable and precise direct qualitative analysis.
  • Kjeldahl is the method of choice for nitrogen and protein determination
  • The very accurate determination of melting or boiling point is a fast way to check the purity level.

With our systems, we provide you rapid and reliable material identity verification of a broad range of solids and liquids material at the point of need. Priority manners are focused on minimizing unwanted effects in the manufacturing process and avoiding defects in the final products.