Particle size, particle concentration and other physical characterization analyses are critical to many environmental applications. Regulatory agencies in the environmental sphere demand strict compliance to standards and discharge regulations. Physical testing of samples for parameters such as particle size and concentration can give insight to the process control engineer on how effective and compliant a discharge handling system is operating. Particulate loading from both air emissions and waste water discharge are monitored in many industry sectors and PTL testing provides valuable supporting data in this monitoring process.
Concurrent with the U.S. Food and Drug Administration’s final rule establishing regulations to require current good manufacturing practices (cGMPs) for dietary supplements, PTL can offer cGMP services to all supplement manufacturers. PTL has sustained its FDA registration since 1994, which involves rigorous inspections by FDA every 2 years or sooner. According to the final rule, proper controls must be in place for dietary supplements to be produced in a consistent manner for identity, purity, strength, and composition. PTL’s particle characterization tests can be conducted following FDA regulations. Valuable testing such as particle size and shape, image analysis, B.E.T. surface area, pore volume and pore size can be analyzed under cGMP compliance. These analyses can give insight into absorption, strength, and composition of the material being processed.
Supporting drug development with pharmaceutical testing is some of the most exciting work we do. As a premier cGMP contract service laboratory, PTL partners with pharmaceutical scientists to identify key physical characteristics of pharmaceutical APIs and excipients ranging from powders, solids and liquids. With over a decade of experience testing a vast array of pharmaceutical products, PTL’s analytical staff uses custom-designed test methods for particle size, particle shape, surface area, pore volume, pore size, thermal analysis, powder flowability and zeta potential analyses.
Serving the abrasive industry over the last 2 decades, the most common testing performed for this field is particle size and shape analysis. The world of abrasives can encompass a host of varying materials from diamond dust, silicon and tungsten carbide, fused silica and quartz, to polished glass and medical abrasives. particle_size_of_abrasives With sizing instrumentation capable of measuring from a few nanometers up to 2000 microns and classic techniques such as sieving for even larger sizes, PTL has the expertise and equipment capable to measure any abrasive type and size. Particle size distribution analyses on abrasives provide valuable insight to engineers in several areas. For example, attrition products from classified spent abrasives can often be seen as a shift to smaller particle sizes.
The continuing establishment of nuclear power stations around the world pose unique environmental challenges for their operators. Ecotech provides air samplers to nuclear power plants for sampling of radionuclides.
A nuclear power plant`s radionuclide monitoring network enables continuous sampling of airborne particles onto sample filters contained within High Volume Air Samplers. These filters are then analysed in a laboratory in order to screen for any radiation releases. The challenge has always been to obtain a sufficiently large volume through the filter in order to exceed the laboratory methods minimum detection limits.
Ecotech`s MegaVol Sampler, samples at a flow rate of between 120-150 m3/hr providing a high flow rate in order to collect a sufficient sample mass for laboratory analysis.
The MegaVol will maintain volumetric flow rate at a preset volume until the filter is either changed or overloaded. The MegaVol can be equipped with a 3G modem in order to remotely monitor flow rate and other diagnostic parameters such as temperature, pressure and wind speed and direction.