Particle Size Distribution Measurement Applications

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AutoChem - Particle and Droplet Processing

Optimize Multiphase Processes With In Situ Video and Real-Time Particle and Droplet Measurements. Particles and droplets are everywhere in the chemical, consumer products, pulp and paper, and petroleum industries. Particles grow, agglomerate, break, dissolve, and change shape - all of which can have an impact on process performance and product quality. To be successful, chemists and engineers must understand and optimize particle size distributions to control process efficiency such as stability, separations, or flow properties. In addition, particle and emulsion distributions must be well controlled to ensure repeatable product yield, shelf life, and bulk density.

By Mettler - Toledo Int. Inc based in Greifensee, SWITZERLAND.

Independent particle characterization services for medical devices industries

Advances in biomedical implant and device technology continue to present new challenges in the area of physical testing. Particle Size Distribution, Surface Area and Porosity measurement data are invaluable to the biomedical researcher. PTL partners with each client to design projects that provide this needed information while controlling the costs of research. Applications have included particle size analysis of wear particles in fluid submitted from implant fatigue studies and pore size analysis of tricalcium phosphate granules compressed into bone grafting media. Evaluation by photomicroscopy and mercury porosimetry of artifical ligament materials have provided insight to researchers on their products.

By Particle Technology Labs based in Downers Grove, ILLINOIS (USA).

Independent particle characterization services for abrasives industries

Serving the abrasive industry over the last 2 decades, the most common testing performed for this field is particle size and shape analysis. The world of abrasives can encompass a host of varying materials from diamond dust, silicon and tungsten carbide, fused silica and quartz, to polished glass and medical abrasives. particle_size_of_abrasives With sizing instrumentation capable of measuring from a few nanometers up to 2000 microns and classic techniques such as sieving for even larger sizes, PTL has the expertise and equipment capable to measure any abrasive type and size. Particle size distribution analyses on abrasives provide valuable insight to engineers in several areas. For example, attrition products from classified spent abrasives can often be seen as a shift to smaller particle sizes.

By Particle Technology Labs based in Downers Grove, ILLINOIS (USA).

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AutoChem - Formulations and Product Development

The particle size distribution is one of the most critical parameters in drug product quality. Real time understanding and control of particles ensures Quality by Design (QbD) in solid and liquid dosage formulation. FBRM and PVM Process Analytical Technologies (PAT) provide in-process real time measurements of particle dimension, particle shape, and particle count. FBRM and PVM are used to promote faster formulation development, improve process confidence, and control batch-to-batch consistency.

By Mettler - Toledo Int. Inc based in Greifensee, SWITZERLAND.

SONARtrac - Dredging - Hopper Vessels

Soil density, hardness, lithology, and sediment particle size distribution can create slurry of variable makeup and density. At a constant pump speed, the slurry will have a variable flow velocity, which is undesirable and potentially dangerous. If the velocity is too low, there is a risk of sand outs in the pipeline. If the velocity is too high, the pump will wear and be inefficient. Traditional velocity flow meters with wetted parts are prone to wear, causing measurement inaccuracies, and require frequent, costly replacements. In addition, the presence of entrained gases may disturb the readings of traditional flowmeters and cause slurry density measurements to be inaccurate.

By CiDRA Corporate Services Inc based in Wallingford, CONNECTICUT (USA).

SONARtrac - Dredging - Cutter Vessels

Cutting efficiency is greatly affected by variability in soil density, hardness, lithology, and sediment particle size distribution. All of these factors create slurry of variable makeup and density. If the dredge pump works at a constant speed, the slurry will have a variable flow velocity, which is undesirable and potentially dangerous. If the velocity is too low, there is a risk of sandouts in the pipeline. If the velocity is too high, the pump will wear and be inefficient. Traditional velocity flowmeters with wetted parts are prone to wear, causing measurement inaccuracies, and require frequent, costly replacements