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spectrometry Applications

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    Analytical instruments for mass spectrometry

    A variety of MS techniques – such as Quadrupole MS, Time-of-Flight (TOF) MS, Ion Mobility Spectroscopy (IMS), etc. have been developed in the past decades, providing new tools for materials analyses. Flow control for mass spectrometry (MS) requires high repeatability and small temperature- and pressure dependency. This is important to achieve a high resolution and instrument resolution. Depending on the size and electrical interface requirements, the Axetris MFC modules or MFC standalone types are the ideal...

    By Axetris Ag based in Kaegiswil, SWITZERLAND.

  • High Pressure Mass Spectrometry for Explosives

    The list of potential explosive threats is much greater and more varied than ever before. Extremist groups the world over continue to find new ways to develop improvised explosive devices (IEDs) and homemade explosive devices (HMEs) using creative and often unexpected deployment methods. To keep pace with these evolving threats, today’s first responders, bomb disposal units, civilian support teams and military require expanded capabilities for rapid threat detection, identification and monitoring at the...

    By 908 Devices Inc. based in Boston, MASSACHUSETTS (USA).

  • Thermal Analysis Mass Spectrometry

    Hiden offers optimized interface coupling to a range of thermal analysis systems including: TGA-MS and TGA/DTA-MS systems: Hiden Isochema IGA - intelligent gravimetric analyser, PerkinElmer-TA Instruments- Netzsch- Mettler Toledo- Seteram Calorimetry: Mass spectrometry for simultaneous evolved gas/calirometry analysis. Evolved gas analysis compliments the calorimetric data providing reaction kinetics data and speciation of reaction off gas. Solid Insertion Probe: An integrated solid insertion probe mass spectromete...

    By Hiden Analytical Ltd. based in Warrington, UNITED KINGDOM.

  • Empowering Traditional Mass Spectrometry System for Biotherapeutics

    Protein-based therapeutics cover a wide range of molecular types, including monoclonal antibodies (mAbs), Fc fusion proteins, and mAbs conjugated with small molecule drugs. The development of protein therapeutics is challenging and requires sensitive analytical techniques. Mass spectrometry (MS) is widely used due to its sensitivity, selectivity, and specificity. MS analysis can now be simplified and automated by integrating this powerful analytical technique with a microfluidic device that incorporates zone...

    By 908 Devices Inc. based in Boston, MASSACHUSETTS (USA).

  • Empowering Traditional Mass Spectrometry System for Proteomics & Peptide Mapping

    Peptide mapping is an essential step in the structural verification of recombinant proteins and biotherapeutic molecules. In this technique, proteins are digested into peptides, fractionated by traditional liquid chromatography (LC) methods and then analyzed by Mass Spectrometry (MS). Although this approach can be effective for many peptides, it is slow (often 30 minutes or more per sample), requires complex sample preparation and is incompatible with some sample types such as “sticky” peptides. The...

    By 908 Devices Inc. based in Boston, MASSACHUSETTS (USA).

  • High Pressure Mass Spectrometry for Priority Drugs

    From the widespread manufacture and trafficking of new and established street drugs to prescription medication diversion, including fentanyl and other opioids, illicit drugs continue to afflict society. First responders, law enforcement officials and border security need immediate analysis on a wide variety of materials with confidence for immediate action. Whether performing checkpoint screening, clandestine lab interdiction or sensitive site exploitation (SSE), new handheld technology that can identify drug...

    By 908 Devices Inc. based in Boston, MASSACHUSETTS (USA).

  • Empowering Traditional Mass Spectrometry System for Metabolomics

    Analysis of small molecule metabolites is fundamental to drug and biomarker discovery, DMPK and toxicology studies, and health and nutrition research. With many metabolite concentrations in rapid flux, analysis of these compounds must be fast, sensitive, and non-disruptive to produce an accurate picture of the metabolic state. Mass spectrometry is a vital tool in the field of metabolomics due to its selectivity and sensitivity. With the ZipChip platform, users can enhance the capabilities of their mass spectrometer...

    By 908 Devices Inc. based in Boston, MASSACHUSETTS (USA).

  • High Pressure Mass Spectrometry for Chemical Threats

    From chemical warfare agents (CWAs), toxic industrial chemicals (TICs), toxic industrial materials (TIMs), precursors, and degradation products to the growing use of unconventional agents, the risk associated with today’s chemical warfare and industrial hazards is more disseminated than ever. These expanding threats require first responders, CBRNE teams and HazMat response units to prepare for the unexpected. The use of advanced handheld analytical technology capable of proactive performance in the hot zone...

    By 908 Devices Inc. based in Boston, MASSACHUSETTS (USA).

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    Determination of heavy metals in food

    This analytical procedure is intended for measuring the content of the elements (cadmium, lead, arsenic, tin, chromium and mercury) in the samples of food products by atomic absorption spectrometry with electrothermal atomization using an “MGA-915M” Graphite Furnace AA Spectrometer. The method is based on measuring resonance radiation absorption that occurs when the radiation passes through a layer of atomic vapor in the electrically heated graphite furnace of the “MGA-915M” AA spectrometer....

    By Lumex Instruments Group based in Mission, BRITISH COLUMBIA (CANADA).

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    Analysis of VOC compounds in water by Purge & Trap or dynamic headspace

    Context & Challenges Volatile organic compounds (VOC) can be dissolved in water. Sometimes water is polluted and to study contamination of VOC in finished drinking water, VOC must be measured. Chromatotec® Solutions Chromatotec® has developed a specific system for the measurement of VOC in water: a Purge & Trap system, the airmoPURGE. The analyzer is coupled with a degasing system allowing the extraction of dissolved gases. The complete system is based on: - 502.2 method from US EPA –...

    By Chromatotec Group based in Val de Virvée, FRANCE.

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    RAPID ANALYSIS OF TOTAL MERCURY IN WASTE WATERS AND PROCESS WATERS WITH ELEVATED MERCURY CONTENT USING DIRECT PYROLYSIS TECHNIQUE

    A conventional standard method of total mercury determination in water using atomic absorption spectrometry (AAS) involves preliminary sample digestion that takes from 30 minutes to 8 hours depending on the digestion conditions. The use of a mercury analyzer RA-915M/RA-915+ with Zeeman background correction in combination with PYRO-915+ pyrolysis attachment provides direct determination of mercury in process and waste waters contaminated with mercury without digestion or any other sample preparation stages. The...

    By Lumex Instruments Group based in Mission, BRITISH COLUMBIA (CANADA).

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    Mass flow devices for analytical instrumentation

    Axetris mass flow devices are used in a variety of analytical applications: Gas Chromatography, Mass Spectrometry, Atomic Spectroscopy, Elemental Analysis, Thermal Analysis, Bioreactor and Fermentor.

    By Axetris Ag based in Kaegiswil, SWITZERLAND.

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    Analytical instruments for atomic spectroscopy

    Besides Mass Spectrometry, a further variety of analysis techniques are categorized as atomic spectroscopy. Analysis techniques which use inductively coupled plasma (ICP), such as ICP-OES and ICP-MS, are among these. With increasing environmental awareness backed by regulations, an increasingly important use of atomic spectroscopy techniques is in mercury analysis. Achieving a high mass flow control performance, e.g. high repeatability or an excellent turn-down ratio, is a prerequisite to achieve a high analyzer...

    By Axetris Ag based in Kaegiswil, SWITZERLAND.

  • Sample analysis for the drug development sector

    DART enables near effortless inspection of tablets, powder, and liquid formulations. Qualitative and quantitative analysis are completed by using commercially available LC/MS systems from all of the major mass spectrometry vendors. Rapid reaction monitoring is facilitated with the development of our Mobile DART-Acquity QDa platform which can move from laboratory to pilot plant in minutes enabling generation of high quality information in seconds to improve your decision making process.

    By IonSense Inc based in Saugus, MASSACHUSETTS (USA).

  • Sample analysis for the forensics sector

    Forensic labs are improving throughput and eliminating backlog by using DART. Presentation of sample and standards is routine and requires just seconds per sample to determine quantity and quality of seized narcotics and OTC drugs of abuse. Synthetic cannabinoids and bath salts are easily detected and identified with confirmation using simple mass spectrometry methods and comparison with NIST library standards. Explosives, arson, counterfeit currency, tax stamps and even drugs in body fluids present no problem...

    By IonSense Inc based in Saugus, MASSACHUSETTS (USA).

  • MBE Desposition Rate Monitoring and Control

    XBS Triple Filter Quadrupoles configured for multiple source monitoring in MBE deposition applications. The custom configured ioniser provides for high stability, high senstivity monitoring of oxides and metals from both k-cell and e-gun sources. MBE monitoring and control. Molecular Beam Studies. Multiple beam source analysis. High Performance RGA. Desorption / Outgassing studies / Bakeout cycles. Chamber / Process gas Contaminants. Hiden XBS mass spectrometers for high precision scientific, process...

    By Hiden Analytical Ltd. based in Warrington, UNITED KINGDOM.

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