John Wiley & Sons, Ltd.

A single‐parameter logistic equation for fitting concentration‐response curves from standard acute ecotoxicity assays

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A set of 69 concentration‐response (CR) curves from five acute ecotoxicity assays was fitted with a two‐parameter logistic equation. High correlation between values of regression parameters suggested similar slopes of the curves. This enabled derivation of the empirical single‐parameter logistic equation with the sole EC50 parameter. Such equation might be useful for evaluation of lower‐quality (preliminary) experimental data and for the reduction of number of test organisms and testing costs. Environ Toxicol Chem © 2013 SETAC

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