Analysis of TNT, RDX, and CL-20 by APCI LC/MS/MS
The detection and characterization of explosives has gained the interest of various analytical laboratories and research
groups around the world.
For the forensic community, trace analysis of explosive residues after arson and terrorism is of critical interest.
Biologists and environmentalists monitor biotransformation of these high energy compounds when evaluating environmental contamination. Other groups, such as the munitions industry, continue to explore the synthesis of novel explosive materials. In all of these examples, investigators need an analytical methodology that is informative, sensitive, and selective as well as robust.
In this application note, LC negative ion APCI-MS/MS is used to characterize and detect trinitrotoluene (TNT), hexahydro- 1,3,5-trinitro-1,3,5-triazine (RDX), and 2,4,6,8,10,12-hexanitro- 2,4,6,8,10,12-hexaazaisowurtzitane (CL-20) (Figure 1).