Antimicrobial activity of ZnO-TiO2 nanomaterials synthesized from three different precursors of ZnO: influence of ZnO/TiO2 weight ratio
In this study, ZnO-TiO nanoparticles were synthesized from three different precursors for ZnO (zinc acetate di-hydrate, zinc nitrate hexahydrate and zinc sulfate heptahydrate) and titanium (IV) isopropoxide for TiO. The prepared nanomaterials were calcined at 500 °C for 3 h and characterized by various physicochemical techniques such as X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FT-IR) and transmission electron microscopy, combined with energy dispersive X-ray spectroscopy (TEM-EDS). The obtained results showed that the crystalline structure, size and morphology of the ZnO-TiO nanoparticles are strongly influenced by the nature of the precursor of ZnO, as well as the ZnO/TiO weight ratio. The antibacterial and antifungal activities of the synthesized nanomaterials were evaluated, in the dark, against five multi-resistant of Gram positive () and Gram negative and ) bacteria and a fungus (), which are pathogenic for humans. The obtained results showed that pure TiO anatase is inactive against the tested strains, while the addition of ZnO to TiO improves noticeably the effectiveness of TiO nanoparticles, depending on the nature of the precursor of ZnO and the ZnO/TiO weight ratio.
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