Keywords: biosensors, imaging ellipsometry, total internal reflection, micro-arrays, nanotechnology, multiple protein reaction, protein interactions, micro-fluidic systems, kinetic measurement, multiple biomolecule reactions
Biosensor with total internal reflection imaging ellipsometry
In order to monitor multiple protein reaction processes simultaneously, a biosensor based on imaging ellipsometry operated in the total internal reflection mode is proposed. It could be realised as an automatic analysis for protein interaction processes with real-time label-free method. Its principle and methodology as well as a demonstration for its applications are presented.