John Wiley & Sons, Ltd.

Deriving bioconcentration factors and somatic biotransformation rates from dietary bioaccumulation and depuration tests

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This study develops, applies and tests a method for deriving empirical bioconcentration factors and somatic biotransformation rate constants from dietary bioaccumulation tests and “simplified” bioaccumulation experiments that measure depuration rates. In this approach, measurement of the chemical concentration in the water is not required. The method aims to improve bioaccumulation assessment, reduce cost and animal use, and shorten experiments. This article is protected by copyright. All rights reserved

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