Abstract : This paper provides an overview of full-scale immersed membrane bioreactor (iMBR) technology applied to Mediterranean wineries. It is based on the cumulative experience on design, commissioning and operation of 8 Spanish and 13 Italian references from 2003 to present day. In all of them Kubota membranes are employed. Market drivers for this treatment technology in the wine industry and comparison with alternatives are presented. The text covers wastewater characterization and flow7 patterns, different flowsheet configurations and pre-treatments, favoured biological conditions and membrane flux, common troubleshooting experiences and also running costs. In plants where reuse initiatives have been undertaken, feedback on water quality and potential uses are explained. Keywords Design; immersed membrane bioreactor; performance; reuse; winery.