Improvement of lactobacillus plantarum aerobic growth as directed by comprehensive transcriptome analysis

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An aerobic Lactobacillus plantarum culture displayed growth stagnation during early growth. Transcriptome analysis revealed that resumption of growth after stagnation correlated with activation of CO2-producing pathways, suggesting that a limiting CO2 concentration induced the stagnation. Analogously, increasing the CO2 gas partial pressure during aerobic fermentation prevented the temporal growth stagnation.

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