chemical exposure Articles

  • 6 Surprising sources of chemical exposure

    6 Surprising sources of chemical exposureWe may be careful with that bottle of bleach, can of paint or the ominous bottle of unknown chemical solution found in the basement. But what about everyday actions that may expose us unknowingly to potentially harmful substances? Read on to find some surprising sources of chemical exposure, and what to do about them. 1 - Shower The ...


    By Allerair Industries

  • Chemical Exposure from Imported Food Products

    Chemical Exposure from Imported Food Products Requirement for Routine Monitoring Due to the large quantities of food being imported by countries in today's global markets, routine monitoring of these imported products for chemical contaminants is essential to ensure compliance with chemical safety regulations. Chemicals that have long been removed from the supply chain for products and ...


    By Creme Global

  • Management of chemical exposure: the limitations of a risk-based approach

    Risk assessment and risk-based management approaches are becoming incorporated into a wide range of disciplines as frameworks for use in critical decision-making pathways. During its rapid expansion, many of the assumptions, subjective judgements and irreducible uncertainties inherent within the risk paradigm are becoming increasingly overlooked. This paper provides a critical review of the ...


    By Inderscience Publishers

  • Occupational Skin Exposure

    The National Institute for Occupational Safety and Health (NIOSH) reports that occupational skin disease is the second most common type of occupational disease, indicating that employee education regarding skin protection is needed. In an occupational setting, employees have the potential to absorb both liquids and gases through their skin.  Skin exposure can occur through direct contact ...


  • What is the REACH of your exposure?

    Margarethe Jaroszewski of 3E Company looks at the extra burden REACH Exposure Scenarios will bring The REACH Regulation went into effect on 1 June 2007, simplifying but also complicating the compliance work for companies manufacturing or importing chemicals in Europe. As a result, all companies manufacturing, importing, distributing or using chemical substances on their own, in mixtures ...


    By Verisk 3E

  • Tof-HRMS: Rescuing low-exposure bioanalysis applications from chemical noise

    The drug development process requires pharmacokinetic (PK) analysis to be performed as part of safety and efficacy studies in both preclinical species and human subjects. For high-sensitivity bioanalysis, liquid chromatography (LC) coupled to a triple quadrupole mass spectrometer (LC-MS/MS) is considered the gold standard for quantification. However, for some low-exposure applications, ...


    By Waters Corporation

  • Relationships between exposure and dose in aquatic toxicity tests for organic chemicals

    There is continuing debate about the merits of exposure‐based toxicity metrics such as median lethal concentration (LC50) versus organism‐based metrics such as Critical Body Residue (CBR) as indicators of chemical toxicity to aquatic organisms. To demonstrate relationships and differences between these two metrics we apply a simple one‐compartment toxicokinetic mass‐balance model for ...


    By John Wiley & Sons, Ltd.

  • Periodic reporting of hazard data, exposure information on existing chemicals

    Arecent co-authored paper1 discussed a number of fundamental changes in U.S. regulation of commercial chemicals that should be considered in revising the Toxic Substances Control Act.2 As discussed in that paper, while the Environmental Protection Agency under TSCA has broad authority to require testing and reporting of hazard and exposure information on existing chemicals via rulemaking, ...


    By Bergeson & Campbell, P.C.

  • Predicting the sensitivity of populations from individual exposure to chemicals: The role of ecological interactions

    Population responses to chemical stress exposure are influenced by nonchemical, environmental processes such as species interactions. A realistic quantification of chemical toxicity to populations calls for the use of methodologies that integrate these multiple stress effects. The authors used an individual‐based model for Daphnia magna as a virtual laboratory to determine the influence of ...


    By John Wiley & Sons, Ltd.

  • iSTREEM®: An approach for broad‐scale in‐stream exposure assessment of “down‐the‐drain” chemicals

    The iSTREEM® model (“in‐stream exposure model”), a web‐based model made freely available to the public by the American Cleaning Institute, provides a means to estimate concentrations of “down‐the‐drain” chemicals in effluent, receiving waters, and drinking water intakes across national and regional scales under mean annual and low flow conditions. We provide an overview of the evolution and ...


    By John Wiley & Sons, Ltd.

  • Highly time‐variable exposure to chemicals—toward an assessment strategy

    Organisms in the environment experience fluctuating, pulsed, or intermittent exposure to pollutants. Accounting for effects of such exposures is an important challenge for environmental risk assessment, particularly given the simplified design of standard ecotoxicity tests. Dynamic simulation using toxicokinetic‐toxicodynamic (TK‐TD) models describes the processes that link exposure with ...


    By John Wiley & Sons, Ltd.

  • Chemical analysis of fish bile extracts for monitoring endocrine disrupting chemical exposure in water: Bisphenol A, alkylphenols and norethindrone

    This study determined concentrations of estrogenic bisphenol A (BPA), nonylphenol (NP), octylphenol (4‐tert‐OP), butylphenol (4‐tert‐BP) and progestogenic norethindrone (NET) by LC‐MS/MS in bile extracts from field fish in Xin'an River and market fish in Shanghai, China. Compared to the field fish, EDC concentrations in market fish bile were at relatively high levels with high detectable ...


    By John Wiley & Sons, Ltd.

  • Reduce OH&S Risk Exposure

    Over the last few years there have been significant studies released that point at chemicals as a major source of many ailments, and for the proliferation of ailments that have become much more common as chemical use has become more widespread. Whilst chemicals have a place in all our lives, many now argue that human and animal exposure to harmful chemicals should be minimised.  If you buy a ...


    By GenEon Australia

  • Application of pocis for exposure assessment of munitions constituents during constant and fluctuating exposure

    Potential use of polar organic chemical integrative samplers (POCIS) for exposure assessment of munitions constituents (MC), including 2,4,6‐trinitrotoluene (TNT) and hexahydro‐1,3,5‐trinitro‐1,3,5‐triazine (RDX), and their breakdown products (aminodinitrotoluenes [ADNTs], diaminonitrotoluenes [DANTs], and hexahydro‐1,3,5‐trinitroso‐1,3,5‐triazine [TNX]), was examined. Loss of MC from the ...


    By John Wiley & Sons, Ltd.

  • What is Probabilistic Food Safety Exposure

    What is Probabilistic Food Safety Exposure Assessment? There are a myriad of chemicals in food products consumed by populations. Each chemical in its own right may not be harmful to the population, but in combination with other chemicals, there may be risk of high levels of exposure to potentially harmful substances. An effective probabilistic exposure assessment needs to handle the ...


    By Creme Global

  • Health implications of mercury exposure in children

    Mercury is a ubiquitous environmental toxin that can produce a wide range of health effects in humans. It is found in three chemical forms: organic, inorganic and elemental (mercury). The sources of exposure are also markedly different for the different forms of mercury. Diet, especially fish and other seafood, is the main source of exposure of the general public to organic mercury. Dental ...


    By Inderscience Publishers

  • Embalmers risk dangerous exposure to Formaldehyde

    Embalmers can be at risk of dangerous exposure to Formaldehyde. ...


    By PPM Technology

  • Development of short, acute exposure hazard estimates: A tool for assessing the effects of chemical spills in aquatic environments

    Management decisions aimed at protecting aquatic resources following accidental chemical spills into rivers and coastal estuaries require estimates of toxic thresholds derived from realistic spill conditions: acute pulse exposures of short duration (h), information which often is unavailable. Most existing toxicity data (median lethal concentration or median effective concentration) come from ...


    By John Wiley & Sons, Ltd.

  • Development of an in-stream environmental exposure model for assessing down-the-drain chemicals in Southern Ontario

    In order to address increased interest from scientists and regulators in quantifying environmental risks associated with release of common down-the-drain consumer products, a single-medium contaminant fate model for the lower St. Lawrence drainage basin in Southern Ontario was developed. The model was built within the pre-existing framework of the iSTREEM® in-stream environmental exposure ...


    By IWA Publishing

  • MEASURING BIOCONCENTRATION FACTORS IN FISH USING EXPOSURE TO MULTIPLE CHEMICALS AND INTERNAL BENCHMARKING TO CORRECT FOR GROWTH DILUTION

    Modern chemical legislation requires the measurement of the bioconcentration factor (BCF) of large numbers of chemicals in fish. The BCF needs to be corrected for growth dilution as fish growth rates vary between laboratories. Two hypotheses were tested: (1) BCFs of multiple chemicals can be measured simultaneously in one experiment, and (2) internal benchmarking using a conservative test ...


    By John Wiley & Sons, Ltd.

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