chemical science Articles

  • Journal publication productivity of women scientists at Bhabha Atomic Research Centre, India

    Contributions in academia especially science and technology are important indicators to gauge the progress and participation of women. The objective of the study was to evaluate the contribution of Bhabha Atomic Research Centre (BARC), India, women scientists. This study analyses 5290 publications in journals for the period 2006–2010. Out these, 1455 (27.50%) publications had at least one author ...


    By Inderscience Publishers

  • OICR-9429

    OICR-9429 is a novel small-molecule antagonist of the Wdr5-MLL interaction with IC50 of 5 uM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly ...


    By MedChemExpress LLC

  • MRT68921

    MRT68921 is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and ...


    By MedChemExpress LLC

  • CBR-5884

    CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly ...


    By MedChemExpress LLC

  • Branaplam(LMI070,NVS-SM1)

    Branaplam (LMI070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and ...


    By MedChemExpress LLC

  • SKF-96365 hydrochloride

    SKF-96365 hydrochloride is a non-selective TRP Channel blocker. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and ...


    By MedChemExpress LLC

  • S63845

    S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor with a Kd of 0.19 nM for human MCL1. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and ...


    By MedChemExpress LLC

  • Delamanid(OPC-67683)

    Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids, cruciala component of the cell wall of the Mycobacterium tuberculosis complex. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and ...


    By MedChemExpress LLC

  • MRT68921 dihydrochloride

    MRT68921 dihydrochloride is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific ...


    By MedChemExpress LLC

  • Glesatinib hydrochloride(MGCD265 hydrochloride)

    Glesatinib hydrochloride is an inhibitor of the MET and Axl receptor tyrosine kinase pathways, which drive tumour growth when altered. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and ...


    By MedChemExpress LLC

  • MI-538

    MI-538 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly ...


    By MedChemExpress LLC

  • Chloroquine diphosphate

    Chloroquine (diphosphate) is an antimalarial and anti-inflammatory drug widely used to treat malaria and rheumatoid arthritis. Chloroquine is an inhibitor of autophagy and toll-like receptors (TLRs). MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, ...


    By MedChemExpress LLC

  • Olmutinib(HM61713, BI 1482694)

    Olmutinib (HM61713, BI-1482694) is an irreversible EGFR tyrosine kinase inhibitor that binds to a cysteine residue near the kinase domain. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific ...


    By MedChemExpress LLC

  • IPI549

    IPI549 is a potent and selective PI3Kγ inhibitor with an IC50 of 16 nM.MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for ...


    By MedChemExpress LLC

  • Phorbol 12-myristate 13-acetate(PMA)

    Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is an activator of SphK through protein kinase C (PKC) activation. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and ...


    By MedChemExpress LLC

  • Naquotinib(ASP8273)

    Naquotinib (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor, with IC50s of 8-33 nM toward EGFR mutants and 230 nM for EGFR. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for ...


    By MedChemExpress LLC

  • Mirogabalin(DS5565)

    Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science ...


    By MedChemExpress LLC

  • SR-3029

    SR-3029 is a potent and ATP competitive CK1δ and CK1ε inhibitor, with IC50s of 44 nM and 260 nM, respectively, and Kis of 97 nM for both kinases. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for ...


    By MedChemExpress LLC

  • AZD0156

    AZD0156 is an oral, potent and selective ATM inhibitor with an IC50 of 0.58 nM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and ...


    By MedChemExpress LLC

  • EAI045

    EAI045 is an allosteric inhibitor of mutant EGFR with IC50s of 1.9, 0.019, 0.19 and 0.002 μM for EGFR, EGFRL858R, EGFRT790M and EGFRL858R/T790M at 10 μM ATP, respectively.MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including ...


    By MedChemExpress LLC

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