dna Articles

  • ANDalyze DNA sensor Technology

    Video describing the use of DNA as a sensor for detecting heavy metal ions in ...


    By ANDalyze

  • The DNA Revolution for Water Professionals

    Imagine trying to solve a problem when you are provided just 1% of the total data. This is essentially the case in analyzing water and wastewater microbiomes. Conventional microbiological testing methods such as culture and microscopy can identify only about 1% of microorganisms that are contained in a ...


    By LuminUltra Technologies Ltd.

  • In vitro physicochemical evaluation of DNA nanoparticles

    We aim to characterise in vitro physiochemical behaviour of DNA nanoparticles that have been developed by our research group based on the biodegradable natural polymers with metal coordination. A polysaccharide, pullulan, was chosen as the vector of plasmid DNA. Diethylenetriamine pentaacetic acid (DTPA) was chemically introduced to the hydroxyl groups of dextran to obtain pullulan-DTPA. When ...


    By Inderscience Publishers

  • Dielectrophoresis as a tool for nanoscale DNA manipulation

    The use of the dielectrophoresis as a tool for DNA manipulation is demonstrated experimentally, using both unmodified 48,500 base pairs long bacteriophage lambda dsDNA (λ-DNA), ∼16 μm in length and 414 base pairs long thiol modified natural dsDNA (avDNA), ∼140 nm in length. We show that both the dsDNA types used, are effectively directed between the planar gold electrodes by the positive ...


    By Inderscience Publishers

  • Impact parameters investigation of DNA immobilisation process on DNA sensor response

    This paper studies impact parameters of DNA sequence immobilisation on DNA sensor response. The parameters were examined including immobilisation time, carbon nanotubes concentration, DNA probe concentration and pH value. The DNA probe sequences were immobilised on surface of microelectrodes by using multi–walled carbon nanotubes (MWCNTs) as mediator. The hybridisation between DNA probe and DNA ...


    By Inderscience Publishers

  • Infomemes and infonomes: in search of knowledge DNA

    Knowledge management requires an understanding of what knowledge is before the management can be meaningful. This paper observes how modules are identified and combined to form solutions in other systems. Once these infonomes and infomemes are identified through decomposition, perhaps a more precise cause-effect mapping may be used for a more efficient information management. Finally, this paper ...


    By Inderscience Publishers

  • Cyclin-specific control of ribosomal dna segregation

    Following chromosome duplication in S phase of the cell cycle, the sister chromatids are linked by cohesin. At the onset of anaphase, separase cleaves cohesin and thereby initiates sister chromatid separation. Separase activation results from the destruction of its inhibitor, securin, which is triggered by a ubiquitin ligase called the ...

  • Biosensors - Using DNA as a biosensor to detect contaminants in water

    Biosensor - Using DNA to detect water contamination.   ...


    By ANDalyze

  • Fungal Pathogens Identified by PCR and DNA Sequencing

    Aspergillus is a type of fungus that is commonly found in the environment and in buildings that have suffered water damage or elevated humidity levels.  For people with weakened immune systems, breathing Aspergillus spores can lead to infections. According to the Centers for Disease Control and Prevention (CDC), “Aspergillosis is an infection caused by a fungus called ...


    By EMSL Analytical, Inc.

  • Molecular mechanisms of gene silencing mediated by DNA methylation

    DNA methylation and chromatin modification operate along a common pathway to repress transcription; accordingly, several experiments demonstrate that the effects of DNA methylation can spread in cis and do not require promoter modification. In order to investigate the molecular details of the inhibitory effect of methylation, we microinjected into Xenopus oocytes a series of constructs containing ...

  • Biodiversity Detectives Solve Mysteries with Environmental DNA

    For years, Monterey Bay Aquarium’s 1.2 million gallon main tank has been a source of thrill for visitors seeking fish-eye views of life in the pounding Pacific Ocean right outside its doors. Now, thanks to advances in DNA sequencing, it’s also becoming a model for how to survey life inthat vast ocean with just a few glasses of water. In a study published last January in ...


    By Ensia

  • The role of genomic DNA and introns in gene transfer

    This paper deals with the advantages of using genomic DNA from developed organs in gene transfer and the production of transgenic organisms. It also discusses the role of introns, the functional genes and how they are integrated into the host genomic. The integrated unfunctional DNA never causes defects or deleterious effects but on the contrary it causes repair and heterosis. The utilisation of ...


    By Inderscience Publishers

  • DNA repair after low doses of ionising radiation

    Exposure of mammalian cells to Ionising Radiation (IR) results in an integrated cellular response in which the activation of cell-cycle checkpoints is coordinated with DNA-repair pathways to optimise the removal of potentially cytotoxic or mutagenic DNA lesions. Radiobiological models have usually been based on observations of the cellular response to high doses of IR delivered acutely. This ...


    By Inderscience Publishers

  • Electrical conduction of calf-thymus DNA molecules

    We present theoretical calculations to explain the behaviour of electrical conduction in calf-thymus DNA molecules trapped between a gap of 10 nm Au electrodes. Our work further explains the experimental I-V data reported for these DNA molecules that shows both large electrical hysteresis and voltage gap. We attribute their data to energy conservation within the molecules and electrons transfer ...


    By Inderscience Publishers

  • Heavy Metals Water Testing Powered by DNA

    Water pollution is a worldwide problem affecting developing and developed countries alike. Heavy metal contaminants are one prevalent type of water pollutant. They are persistent in the environment once d is charged and removal from source waters is necessary to ensure a clean drinking water supply. The problem of heavy metal pollution arises from several sources. Heavy metals such as uranium can ...


    By ANDalyze

  • DNA and genetic code: a candidate for nano devices

    The last century has witnessed a tremendous miniaturisation of electronic devices and nanotechnology. Biomolecules like DNA are the likely candidates for nanodevices. Molecular recognition, programmability, self assembling capabilities and biocompatibility are some unique features of DNA. DNA based nanotechnology exploit the properties and symmetries of DNA and the genetic code. In the present ...


    By Inderscience Publishers

  • DNA polymorphisms reveal geographic races of reed canarygrass

    Reed canarygrass (Phalaris arundinacea L.) is a cool-season perennial with a circumglobal distribution in the northern hemisphere, native to Europe, Asia, and North America. Repeated introductions of European germplasm into North America have created confusion over the origins of reed canarygrass germplasm found in wetlands, pastures, and breeding programs. The objectives of this study were to ...

  • DNA nanoparticles for gene delivery to cells and tissue

    The development over the past decade of methods for delivering genes to mammalian cells has stimulated great interest in the possibility of treating human disease by gene-based therapies. The major aim of gene therapy is to effectively deliver the genetic materials into cells, genetically modifying and repairing cell functions, which may induce therapeutic healing of disease conditions. This ...


    By Inderscience Publishers

  • Alterations of DNA and Chromatin Structures at Telomeres and Genetic Instability in Mouse Cells Defective in DNA Polymerase

    Telomere length is controlled by a homeostatic mechanism that involves telomerase, telomere-associated proteins, and conventional replication machinery. Specifically, the coordinated actions of the lagging strand synthesis and telomerase have been argued. Although DNA polymerase , an enzyme important for the lagging strand synthesis, has been indicated to function in telomere metabolism in yeasts ...

  • Nucleic acid (dna, rna) quantification and rna/dna ratio determination in marine sediments: comparison of spectrophotometric, fluorometric, and highperformance liquid chromatography methods and estimation of detrital dna

    In this study, we compared three methods for extraction and quantification of RNA and DNA from marine sediments: (i) a spectrophotometric method using the diphenylamine assay; (ii) a fluorometric method utilizing selective fluorochromes (thiazole orange for total nucleic acids and Hoechst 33258 for DNA); and (iii) a high-pressure liquid chromatography (HPLC) method ...

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