good laboratory practice Articles

Short term fish reproduction assays with methyl tertiary butyl ether (MTBE) with zebrafish and fathead minnow: Implications for evaluation of potential for endocrine activity

This paper reports on short‐term fish reproduction assays in zebrafish and fathead minnow conducted to examine the potential for methyl tertiary butyl ether (MTBE) to cause effects on the endocrine system. Both studies were performed under Good Laboratory Practice and in accordance with OECD and USEPA test guidelines. Results of the first study demonstrated that exposure to a high test ...

Apr. 13, 2015

By John Wiley & Sons, Ltd.

Bruker Launches Stand-Alone FTIR Imaging Microscope LUMOS II

Bruker Corporation today announced the launch of the automated, stand-alone FTIR imaging microscope LUMOS II, which provides ultrafast FTIR imaging capabilities based on modern focal-plane array (FPA) detector technology in its high-end version. The new LUMOS II is designed to identify particles, to determine coatings and contaminations, and to reveal polymeric compositions. The LUMOS II can be ...

Oct. 24, 2019

By Bruker Corporation

China in Talks to Join the OECD System for the Mutual Acceptance of Data in Assessment of Chemicals

It has recently been reported that China is in discussions with the Organization for Economic Cooperation and Development (OECD) to become a provisional adherent to the Mutual Acceptance of Data (MAD) system. This would require China to accept data from safety testing of chemicals from participating countries generated under the MAD conditions and to establish a Good Laboratory Practice (GLP) ...

Jul. 2, 2014

By Bergeson & Campbell, P.C.

Leak Detection in Biotechnology Laboratories

Pharmaceutical and biotechnological companies use gases in a wide range of applications across all stages of the production chain. Pharmaceutical and biotechnological companies use many variants of gas and chemicals – from high purity gases in the laboratory to process gases in production processes such as chemical synthesis, sterilisation gases and gases to ...

Sep. 10, 2019

By Ion Science Ltd.

REACHing Asia: Recent trends in chemical regulations of China, Japan and Korea

Will EU REACH (Registration, Evaluation, Authorisation and Restriction of Chemical substances) influence and change the chemical regulatory systems of Asia, as EU RoHS has done in China, Japan and Korea? The answer is YES. China, Japan and Korea are (or will be) filling the regulatory gap they see between REACH and their chemical regulatory systems. With its advanced chemical regulatory system ...

May 1, 2008

By Enhesa - Global EHS & Product Compliance Assurance

Codelco selects Thermo Scientific SampleManager LIMS™ to improve productivity and efficiency - Case Study

The Corporacion Nacional del Cobre de Chile (Codelco) is the main copper producer in the world, controlling approximately 20 percent of the world's copper reserves. Established in 1976, Codelco was created out of a 1971 Chilean constitutional reform that nationalized the copper industry. Codelco was established to operate and manage the mining properties given to the Chilean State as part of the ...

Dec. 16, 2015

By Thermo Fisher Scientific, LIMS & Laboratory Software

Recommendations for Implementing a Calibration Program

Introduction This article is limited to the principles of organization for calibration work in relation to cGMP and other pharmaceutical standards. Calibration and metrology methods related to actual calibration techniques, statistics, and theories are not explored in our discussions.1 Each class of instruments requires specific techniques and approaches to achieve stated accuracies. All members ...

Nov. 1, 2003

By Prime Technologies, Inc.

Lauren M. Graham, Ph.D., Joins B&C Consortia Management

Bergeson & Campbell, P.C. (B&C®), The Acta Group (Acta®), and B&C® Consortia Management (BCCM) are pleased to announce that Lauren M. Graham, Ph.D., has joined our firms as Manager, BCCM. In this role, Dr. Graham will guide and facilitate effective consortia performance in advocacy programs, public outreach, product stewardship, and testing and compliance. She offers ...

Nov. 7, 2016

By Bergeson & Campbell, P.C.

Matrix Gemini Lims at work in Cancer research trials case study

Executive Summary The Roy Castle Lung Cancer Foundation (RCLCF) is a UK wide charity, dedicated to the defeat of lung cancer. It funds basic science research, tobacco control initiatives and work in lung cancer patient information, support and advocacy. RCLCF works towards defeating lung cancer through research, campaigning and education and gives practical and emotional support for patients and ...

Mar. 23, 2016

By Autoscribe Informatics

Water Quality Analysis Safeguarding Families

Water is intensely purified and treated by water authorities before being ready for thousands of families. Everybody expects clean and safe tap water when turning on their taps. A water quality analysis center in Shanghi, China excels in its water testing and analysis with fully automatic potentiometric titration. Traditional Water Quality Analysis In order to ensure water hygiene and ...

Apr. 15, 2010

By Mettler - Toledo Int. Inc

Matrix express makes Water testing lab more efficient case study

Matrix Express LIMS allowed The Water Lab to improve its efficiency and provide a faster service by streamlining the processing and management of sample information. The Water Lab (www.lhewaterlab.ie/) is a modern, fully calibrated ISO17025 environmental contract laboratory based in Co. Kildare, Ireland. Providing a wide range of water and waste water testing services, including sampling and ...

Mar. 23, 2016

By Autoscribe Informatics

Syngenta Settles with EPA on Alleged Label Violations

On September 16, 2016, the U.S. Environmental Protection Agency (EPA) announced it settled an enforcement matter with Syngenta Crop Protection, LLC (Syngenta or Respondent) via a Consent Agreement and Final Order (CAFO) concerning EPA’s allegations that Syngenta violated the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA) and EPA’s Pesticide Container and Containment Rule ...

Sep. 19, 2016

By Bergeson & Campbell, P.C.

Endocrine Disruptors

Overview: Substances that mimic, influence, or interfere with the body's endocrine system at certain doses, and produce potentially adverse developmental, reproductive, neurological, and/or immune effects in both humans and wildlife, are called endocrine disruptors. These substances can be naturally-occurring or man-made. Endocrine issues have long been the subject of intense regulatory interest ...

Oct. 5, 2015

By Bergeson & Campbell, P.C.

3 Steps to Choosing a High Quality Filter Element

The primary function of a hydraulic filter is to remove contaminants as oil flows through a permeable element called the media. The quality of the element determines how well a filter can function. It may be surprising to learn that 75 per cent of all system failures in hydraulic machinery are caused by contamination. This can lead to significant economic loss for any project due to downtime ...

Nov. 6, 2015

By Fluid Line Services

The Chemical Safety Improvement Act: An In-Depth Review and Analysis

In a stunning bipartisan show of support for reform of the Toxic Substances Control Act (TSCA) that few saw coming, Senators David Vitter (R-LA) and Frank Lautenberg (D-NJ) (among bipartisan others) introduced on May 22, 2013, the Chemical Safety Improvement Act (CSIA), later designated S. 1009, available online. CSIA provides a new and streamlined approach to reform TSCA that stakeholders may ...

May 29, 2013

By Bergeson & Campbell, P.C.

Toxicological and Environmental Safety Data - Case Study

Introduction AGRAGEL is a cross-linked copolymer of acrylic acid and acrylamide partially neutralized as potassium/ ammonium salt. The polymer is in its dry form a granulate and forms a gel-like material upon addition of water or aqueous solutions. Due to the cross-linking it is insoluble in water. Uptake of water is facilitated mainly by the negative carboxylic groups of the polymer and their ...

Nov. 21, 2016

By Terawet Green Technologies, Inc. (TGT)

Discrete or Continuous Flow Analysis – which is better?

A wide variety of factors affect the choice of analytical instrument. These include target workload (samples/hour), variety of chemistries, methods required, bench space, staff availability etc. In the following article Lalicia Potter, Technical Sales & Support Director at SEAL Analytical, examines one of the common decisions facing laboratory managers. As the manufacturer of an ...

Jan. 13, 2014

By SEAL Analytical, Inc.

How Top Pharma Companies Evaluate Industry Trends and the Human Element in Containment

ABSTRACT Engineering controls designed to mitigate exposure and create separation between the operator and the toxic material are available in many different forms, all with their own unique advantages and risks. This article will look into various forms of containment while asking the question, is your liability assured or insured? ASSURANCE VS INSURANCE Assurance is defined as a positive ...

Jun. 4, 2020

By Flow Sciences, Inc.

The Value and Importance of Testing

The primary mission of Flow Sciences is to contain hazardous materials. We maintain a laboratory for containment performance verification, relevant standard testing, and product development. We test every unique enclosure that is manufactured for reliable performance. Merck has chosen many times with us to verify containment performance further through surrogate powder testing. Recently we ...

Jul. 6, 2020

By Flow Sciences, Inc.

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