Abstract The US Pharmacopeia recently released USP as the current monograph for determining residual solvents in pharmaceutical products by static headspace. The USP classified these residual solvents into 3 categories; Class 1, Class 2 and Class 3. This headspace method does not require further validation if the USP parameters are followed. Following USP monograph parameters, this study ...
Abstract The US Pharmacopeia recently released USP as the current monograph for determining residual solvents in pharmaceutical products by static headspace. The USP classified these residual solvents into 3 categories; Class 1, Class 2 and Class 3. This headspace method does not require further validation if the USP parameters are followed. Following USP monograph parameters, this study ...
Introduction The Korean Method ES 04601.2 requires static headspace with GC/MS to monitor 1,4-dioxane. The Minimum Quantitation Limit (MQL) must be less than 1 ppb. The method requires the calibration curve to have a correlation coefficient greater than 0.98, or a relative standard deviation of the response factors less than 25%. The Teledyne Tekmar HT3 Automated Static and Dynamic Headspace Vial ...
Abstract A static headspace method was developed using Teledyne Tekmar automated headspace vial samplers (Figure 1 and Figure 2) to meet the method requirements of the Alcohol and Tobacco Tax and Trade Bureau of the US Department of the Treasury (TTB) method SSD: TM:2001 for testing fusel alcohols in alcoholic beverages. Read the full article Click ...
Abstract The Ministry of Environment of the Republic of Korea recently updated the Korean Standard Method for Water Pollution to include seven new harmful substances to the list of compounds subject of wastewater discharge standards from 35 to 42. One of the methods specified in this update for three of the seven new compounds, bromoform, vinyl chloride and acrylonitrile is ES04602.1 utilizing ...
Abstract With chemists engineering new “designer drugs” everyday, law enforcement and regulatory bodies need testing to quickly and accurately determine the composition of these compounds. This study will present a static headspace method for rapidly determining drug components for use in forensic applications. A Teledyne Tekmar HT3 Headspace Analyzer will be used to examine bath salt ...
Introduction The Korean Method ES 04602.1b requires either static or dynamic headspace with GC/MS to monitor vinyl chloride, acrylonitrile, and bromoform. The Minimum Quantitation Limit (MQL) must be less than 5 ppb. The method requires the calibration curve to have a correlation coefficient greater than 0.98 or a Relative Standard Deviation (RSD) of the Response factors (Rf) less than 25%. The ...
Introduction The Korean Standard Method for Drinking Water ES 04607.1 requires static headspace with GC/MS to monitor naphthalene. The Minimum Quantitation Limit (MQL) must be less than 3 ppb. The method requires the calibration curve to have a correlation coefficient greater than 0.98 or a Relative Standard Deviation (RSD) of the Response factors (Rf) less than 25%. The Teledyne Tekmar HT3 ...
Abstract The US Food and Drug Administration (FDA) published the results of a survey of furan in canned and jarred foods that undergo heat treatment in 2004. In the same year, the European Food Safety Authority agreed with the findings of the FDA report and determined that more research was needed on the study of furan in food. One of the techniques used by the FDA for furan in the foods that ...
Introduction Recently, Teledyne Tekmar released the Versa, their latest innovative headspace instrument. Initially developed for the pharmaceutical industry to provide an economical headspace system for residual solvent analysis, the Versa can provide forensic/toxicology laboratories similar benefits. Blood alcohol analysis is one of a variety of headspace methods performed in ...
Why does headspace gas need to be measured? To check the continuity and quality of the gas supply to the packing machine, the efficiency of the flush/vacuum cycle and the integrity of the pack seal. To optimise gas usage and save costs. To meet customer headspace gas quality standards. To present quality data to auditors, food quality inspectors or as part of a quality process e.g. ...
Abstract High density polyethylene (HDPE) and polyethylene terephthalate (PET) are widely used polymers for the storage of consumer products including bottled drinks. HDPE is typically used in milk jugs while PET is typically used in soft drink and bottled water bottles. These polymers can have glass transition temperature above 250°C (482°F) and can be difficult for most headspace ...
Abstract Eight commercially available beverage samples were selected for low-level detection of benzene by static headspace analysis. This study will use the Teledyne Tekmar HT3 Automated Headspace Vial Sampler to analyze parts per trillion (ppt) levels of benzene in beverages. A GC/MS system will be employed in full scan/SIM mode for separation and detection of benzene, as well as other volatile ...
Abstract Coffees have aroma and taste based on where the beans are grown, roasting techniques, and flavor additives. One component of the bean responsible for the aroma and some of the taste are volatile organic compounds (VOCs). Furan is one VOC that has recently been investigated in food (1). An FDA method for furan in food uses static headspace and requires 30 min of incubation time at 60 ...
Introduction The Korean Standard Method for Drinking Water ES 04605.3 requires static headspace with Gas Chromatograph/Mass Spectrometer (GC/MS) to monitor formaldehyde. The method is based on the derivatization of formaldehyde with O-(2,3,4,5,6-pentafluorobenzyl) hydroxylamine (PFBHA) to form the pentafluorobenzyl oximine compound within a static headspace vial. The method requires that the ...
Introduction Analysis of biological fluids for volatile components by headspace analysis is routinely used by forensic laboratories around the world. One of the more common of these headspace analyses is the determination of blood alcohol in cases involving suspected DUI or OVI. This determination is typically accomplished with an injection of the sample onto two columns, one for quantitation and ...
Introduction Since the early 1990’s air quality in enclosed spaces such as office buildings, homes and automobiles has become a major environmental concern. The concern is that man made materials used in these environments release volatile (VOC) and semivolatile organic compound (SVOC) reducing air quality in these environments. Manufactures of materials used in these environments have ...
Introduction The Korean Standard Method for Drinking Water ES 04603.2b requires static headspace with GC/MS to monitor 12 Volatile Organic Compounds (VOCs). The Minimum Quantitation Limit (MQL) must be less than 5 ppb. The method requires the calibration curve to have a correlation coefficient greater than 0.98 or a Relative Standard Deviation (RSD) of the Response factors (Rf) less than 25%. ...
Abstract Hexanal is one of many well-documented aromatic components that contribute to flavor and aroma in common consumer food products containing omega-6 fatty acids. Hexanal content is also used to measure the oxidative status of foods rich in omega-6 fatty acids. Dynamic headspace sampling differs from static headspace sampling in that the headspace above the sample is swept with a gas onto ...
Abstract The Ministry of Environment of the Republic of Korea recently updated the Korean Standard Method for Drinking Water to include seven new harmful substances to the list of compounds subject of wastewater discharge standards from 35 to 42. One of the methods specified in this update for drinking water is ES05602.3 utilizing static headspace with GC/MS to monitor 1,4-dioxane, one of the ...