headspace Articles
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USP <467> Headspace Residual Solvent Assay with a HT3 Headspace Instrument
Abstract The US Pharmacopeia recently released USP as the current monograph for determining residual solvents in pharmaceutical products by static headspace. The USP classified these residual solvents into 3 categories; Class 1, Class 2 and Class 3. This headspace method does not require further validation if the USP parameters are followed. Following USP monograph parameters, this study ...
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Meeting the Korean Method ES 04601.2 for 1,4-Dioxane with Static Headspace GC/MS
Introduction The Korean Method ES 04601.2 requires static headspace with GC/MS to monitor 1,4-dioxane. The Minimum Quantitation Limit (MQL) must be less than 1 ppb. The method requires the calibration curve to have a correlation coefficient greater than 0.98, or a relative standard deviation of the response factors less than 25%. The Teledyne Tekmar HT3 Automated Static and Dynamic Headspace Vial ...
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USP <467> Headspace Residual Solvent Assay with a HT3 Headspace Instrument
Abstract The US Pharmacopeia recently released USP as the current monograph for determining residual solvents in pharmaceutical products by static headspace. The USP classified these residual solvents into 3 categories; Class 1, Class 2 and Class 3. This headspace method does not require further validation if the USP parameters are followed. Following USP monograph parameters, this study ...
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Using the Teledyne Tekmar HT3 Headspace Analyzer to Meet the Requirements of the New Korean Standard Method for Water Pollution, ES04602.1, for Bromoform, Vinyl Chloride and Acrylonitrile
Abstract The Ministry of Environment of the Republic of Korea recently updated the Korean Standard Method for Water Pollution to include seven new harmful substances to the list of compounds subject of wastewater discharge standards from 35 to 42. One of the methods specified in this update for three of the seven new compounds, bromoform, vinyl chloride and acrylonitrile is ES04602.1 utilizing ...
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Alcoholic Beverage Fusel Alcohol Testing with Static Headspace
Abstract A static headspace method was developed using Teledyne Tekmar automated headspace vial samplers (Figure 1 and Figure 2) to meet the method requirements of the Alcohol and Tobacco Tax and Trade Bureau of the US Department of the Treasury (TTB) method SSD: TM:2001 for testing fusel alcohols in alcoholic beverages. Read the full article Click ...
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Meeting the Korean Method ES 04602.1b for Vinyl Chloride, Acrylonitrile, and Bromoform with Static and Dynamic Headspace GC/MS
Introduction The Korean Method ES 04602.1b requires either static or dynamic headspace with GC/MS to monitor vinyl chloride, acrylonitrile, and bromoform. The Minimum Quantitation Limit (MQL) must be less than 5 ppb. The method requires the calibration curve to have a correlation coefficient greater than 0.98 or a Relative Standard Deviation (RSD) of the Response factors (Rf) less than 25%. The ...
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Evaluating Food Products for Furan and Other Volatile Organic Compounds
Abstract The US Food and Drug Administration (FDA) published the results of a survey of furan in canned and jarred foods that undergo heat treatment in 2004. In the same year, the European Food Safety Authority agreed with the findings of the FDA report and determined that more research was needed on the study of furan in food. One of the techniques used by the FDA for furan in the foods that ...
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Evaluating Consumer Products for Low Level Contaminants with High Temperature Dynamic Headspace
Abstract High density polyethylene (HDPE) and polyethylene terephthalate (PET) are widely used polymers for the storage of consumer products including bottled drinks. HDPE is typically used in milk jugs while PET is typically used in soft drink and bottled water bottles. These polymers can have glass transition temperature above 250°C (482°F) and can be difficult for most headspace ...
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Determination of Furan in Coffee by Static and Dynamic Headspace-GC–MS
Abstract Coffees have aroma and taste based on where the beans are grown, roasting techniques, and flavor additives. One component of the bean responsible for the aroma and some of the taste are volatile organic compounds (VOCs). Furan is one VOC that has recently been investigated in food (1). An FDA method for furan in food uses static headspace and requires 30 min of incubation time at 60 ...
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Meeting the Korean Method ES 04607.1 for Naphthalene with Static and Dynamic Headspace GC/MS
Introduction The Korean Standard Method for Drinking Water ES 04607.1 requires static headspace with GC/MS to monitor naphthalene. The Minimum Quantitation Limit (MQL) must be less than 3 ppb. The method requires the calibration curve to have a correlation coefficient greater than 0.98 or a Relative Standard Deviation (RSD) of the Response factors (Rf) less than 25%. The Teledyne Tekmar HT3 ...
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Headspace gas analysis video
Why does headspace gas need to be measured? To check the continuity and quality of the gas supply to the packing machine, the efficiency of the flush/vacuum cycle and the integrity of the pack seal. To optimise gas usage and save costs. To meet customer headspace gas quality standards. To present quality data to auditors, food quality inspectors or as part of a quality process e.g. ...
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Meeting the Korean Method ES 04605.3 for Formaldehyde with Static Headspace GC/MS
Introduction The Korean Standard Method for Drinking Water ES 04605.3 requires static headspace with Gas Chromatograph/Mass Spectrometer (GC/MS) to monitor formaldehyde. The method is based on the derivatization of formaldehyde with O-(2,3,4,5,6-pentafluorobenzyl) hydroxylamine (PFBHA) to form the pentafluorobenzyl oximine compound within a static headspace vial. The method requires that the ...
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Bath Salt Characterization using the Tekmar HT3 Headspace Analyzer and GC/MS
Abstract With chemists engineering new “designer drugs” everyday, law enforcement and regulatory bodies need testing to quickly and accurately determine the composition of these compounds. This study will present a static headspace method for rapidly determining drug components for use in forensic applications. A Teledyne Tekmar HT3 Headspace Analyzer will be used to examine bath salt ...
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Using the Teledyne Tekmar HT3TM Headspace Analyzer to Meet the Requirements of the Korean Standard Method for Drinking Water, ES05602.3, for 1,4-Dioxane
Abstract The Ministry of Environment of the Republic of Korea recently updated the Korean Standard Method for Drinking Water to include seven new harmful substances to the list of compounds subject of wastewater discharge standards from 35 to 42. One of the methods specified in this update for drinking water is ES05602.3 utilizing static headspace with GC/MS to monitor 1,4-dioxane, one of the ...
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Meeting the Korean Method ES 04603.2b for 12 VOC with Static and Dynamic Headspace GC/MS
Introduction The Korean Standard Method for Drinking Water ES 04603.2b requires static headspace with GC/MS to monitor 12 Volatile Organic Compounds (VOCs). The Minimum Quantitation Limit (MQL) must be less than 5 ppb. The method requires the calibration curve to have a correlation coefficient greater than 0.98 or a Relative Standard Deviation (RSD) of the Response factors (Rf) less than 25%. ...
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Two Headspace Solutions for the Analysis of Dissolved Gases in Water by Method RSKSOP-175
Abstract Dissolved gas analysis has been performed using a simplified headspace method following US EPA method RSKSOP-175. This method describes the preparation and analysis of dissolved gases in water. Recent developments in natural gas drilling from deep underground shale formations, using techniques such as hydraulic fracturing, have renewed interest in this method to determine dissolved gases ...
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Determination of Bisphenol A in Drinking Water
A comprehensive sample preparation and analytical procedure was developed for determining BPA in drinking water. This fast procedure employed materials and techniques selected in part for speed, but also those that would not contribute unwanted artifacts. The use of SPE allowed BPA to be extracted plus concentrated, which may result in greater method sensitivity compared to simple headspace or ...
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Determination of Hexanal in Foods Utilizing Dynamic Headspace GC/MS
Abstract Hexanal is one of many well-documented aromatic components that contribute to flavor and aroma in common consumer food products containing omega-6 fatty acids. Hexanal content is also used to measure the oxidative status of foods rich in omega-6 fatty acids. Dynamic headspace sampling differs from static headspace sampling in that the headspace above the sample is swept with a gas onto ...
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Study of Residual Solvents in Various Matrices by Static Headspace
Abstract United States Pharmacopeia (USP) chapter is a widely used method for identifying and quantifying Organic Volatile Impurities (OVI) used in the production of pharmaceuticals. Many of these OVIs, also known as residual solvents, are known or potential carcinogens and must be monitored due to the risks they pose to consumers and the environment. For this study, VOC data will be presented ...
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Detection Limits of EPA Method 8260 with Static and Dynamic Headspace GC-MS Analysis
Abstract EPA Method 8260 provides for the analysis of volatile organic compounds (VOC) in various solid waste matrices. The referenced EPA Method 5021, allows for the introduction of VOCs from solid samples by automated static headspace. The static headspace method permits the prescreening of samples to minimize over saturation of the chromatography system. The Teledyne Tekmar HT3 static and ...
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