hplc detector Articles

  • Tips to maintain your HPLC & UHPLC systems and columns

    Recently, Ade Kujore (Cecil Instruments), Tracie Brombos (GenTech Scientific) and I were asked by Angelo De Palma, a well-respected writer for Lab Manager magazine, to contribute to an article about maintaining and caring about your laboratory instruments. Here are my tips/best practices for column and HPLC/UHPC/UPLC system maintenance. Maintaining your ...


    By Waters Corporation

  • Reverse-phase HPLC method for the simultaneous analysis of triclosan and triclocarban in surface waters

    A validated reverse-phase HPLC-DAD for the simultaneous determination of triclosan and triclocarban in surface water has been developed, because this method has not been used for determination of these disinfectant agents so far. An isocratic elution was achieved using a Develosil RP Aqueous AR-5 RP-30 column with a flow rate of 1.0 mL min−1. The mobile phase consisted of mixed methanol and water ...


    By IWA Publishing

  • SPE Cleanup of Wheat Extracts Prior to the HPLC Analysis of the Mycotoxin Deoxynivalenol

    Deoxynivalenol (DON) is a mycotoxin produced by the Fusarium fungal species graminearum and culmorum. These Fusariumfungi infect cereal crops primarily in wet conditions when temperatures range from 15–30 °C, resulting in grain head damage and DON contamination ...


    By Sigma-Aldrich Co., LLC

  • Development of a Cleaning Validation Method for MICRO® A07 Citric Acid Cleaner Using HPLC-CAD

    Abstract A high performance liquid chromatography (HPLC) method with a Corona Charged Aerosol detector for the cleaning validation of MICRO* A07 Citric Acid Cleaner residue has been developed. The pooled average repeatability of 3 replicates at 6 concentration levels expressed as RSD was 1.3 % while the pooled average intermediate precision (intra-day repeatability in 3 days) of 3 replicates ...

  • High-Performance Liquid Chromatography for Determination of N-Nitrosodimethylamine in Water

    High-performance liquid chromatography (HPLC) was applied for aqueous determination of Nnitrosodimethylamine (NDMA). A fluorescence derivatization technique was adopted to enhance detection using HPLC. Derivatization with dansyl chloride was optimized for excitation and emission wavelengths (340 and 530 nm, respectively), pH (9-12), and concentration of dansyl chloride (500 mg/L). An instrumental ...

  • Influence of environmental factors on degradation of carbendazim by Bacillus pumilus strain NY97-1

    The influence of environmental factors on the performance of carbendazim degradation by Bacillus pumilus strain NY97-1 was investigated under aerobic conditions. The carbendazim degradation in culture medium was characterised by High-Performance Liquid Chromatography (HPLC) with UV detector. When the initial concentration of carbendazim was 10, 30, 50, 100, 300 mg/L, the degradation rate was ...


    By Inderscience Publishers

  • o-Phthalaldehyde Reagent

    Introduction Primary amines form highly fluorescent adducts when reacted with o-Phthalaldehyde (OPA) and a mercaptan under basic conditions. At a pH>9 and ambient temperature, reaction is generally complete within 30 seconds. The products of this reaction, 1-alkyl-2-alkylthio-substituted isoindoles, exhibit optimal excitation at 330 nm and maximal emission at 465 nm. The reagents ...


    By Pickering Laboratories, Inc.

  • Rapid raw material identification for formulation compounds using handheld Raman technology

    Ever since the European Medicines Agency (EMA) recommended that all pharmaceutical companies test every raw material that passes through their manufacturing facilities, this practice has attracted great interest in the nutraceuticals, food manufacturing, cosmetics, and agricultural industries, pushing them to strive for more rigorous and technology-oriented quality control standards. In recent ...


    By B&W Tek

  • Glyphosate and AMPA in drinking water

    Carcinogenic or not? The broad-spectrum herbicide glyphosate is used all over the world in agriculture. Alongside farming, the chemical is also used for weed-killing in domestic gardens and in public and private spaces kept free from «vegetal invasion», such as railway tracks. Glyphosate has been used since the 1970s in pesticides and was hitherto thought to be harmless at ...


    By Metrohm AG

  • Simon Fraser University Opens Suite of Mass Spectrometers for Natural Products Discovery Research

    As a graduate student at the University of British Columbia, Dr. Roger Linington discovered his future life’s work serendipitously. While studying sponges, it became clear to him that one of the challenges in studying macroorganisms is their limited or slowly replenishing supply. To perform mechanism and mode-of-action studies, he needed a larger, more accessible source of ...


    By Waters Corporation

  • LC/MS/MS analysis of metabolites of synthetic Cannabinoids JWH-018 and JWH-073 in Urine

    Abstract A liquid chromatographic method was developed to resolve a comprehensive set of metabolites of JWH-018 and JWH-073. In addition to the chromatographic analysis method, an extraction method was developed to recover a broad range of synthetic cannabinoid metabolites, including carboxylic acid metabolites that are not traditionally recovered using a high pH liquid/liquid extraction. ...


    By Restek Corporation

  • Better tools for fast and convenient Patulin analysis

    Analytical Standards and New SupelMIP SPE Cartridges The mycotoxin patulin is often found in rotten apples. It is mostly produced by Aspergillus, Penicillium and Byssochlamys and shows a variety of short-term and long-term effects in animal studies, ranging from gastrointestinal problems and neurotoxicity to genotoxicity and teratogenicity. Therefore, many countries set limits for patulin ...


    By Sigma-Aldrich Co., LLC

Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you