hplc system design Articles

  • ACQUITY Arc System: Transferring Validated HPLC Methods within USP Guidelines

    The thought of transferring established high performance liquid chromatography (HPLC) methods onto a another vendor’s LC, or a new platform like UHPLC/UPLC, may cause a bit of anxiety for those that may be unaware of how easy it can be. The reason that the topic of analytical method transfer induces so much angst is that for the transfer of an LC method to succeed, the method has to work as ...


    By Waters Corporation

  • The development of cation-exchange chromatography in free amino acids analysis

    Although it was not called a liquid chromatograph, the first such instrument was introduced in late 1959 by Beckman Instruments and was designated the M.S. Amino Acid Analyzer in honour of Moore and Stein. Inject valves had yet to be invented, the buffer switching valves were glass stopcocks and the column temperature was controlled by circulating water baths. Two positive displacement pumps ...


    By Pickering Laboratories, Inc.

  • Pinnacle PCX Carbamate Testing at Nebraska Health

    Beta Site Evaluation of the EPA Carbamate in Drinking Water Method 531.1 with Pickering Laboratories Pinnacle PCX Integrated LC/Post-Column Derivatization Instrument. The Nebraska DHHS Public Health Environmental Laboratory conducts environmental testing for the state of Nebraska. It employs mandated U.S. Environmental Protection Agency (EPA) methods for the determination of regulated substances ...


    By Pickering Laboratories, Inc.

  • Matrix LIMS configured and implemented within 3 months case study

    Laboratory staff at Glatfelter have established an extremely close, ongoing working relationship with Autoscribe. This has allowed the design and implementation in just 3 months of a configured Matrix Gemini LIMS for the company's corporate analytical services group. Organisation Established since 1864, global paper supplier Glatfelter has expanded its product range from high-quality ...


    By Autoscribe Informatics

  • Screening of fruits, vegetables, and feeds for carbamates - strategic diagnostics inc.’s, inquest op/carbamate screen

    I. PURPOSE - The purpose of this document is to detail the standard operating procedure for the screening of cholinesterase inhibiting carbamate insecticides in fruits, vegetables, and feeds using the SDI Food Prep Kit and InQuest OP/Carbamate Screening Kit. NB - This is a screening technique designed to determine presence or absence of cholinesterase inhibiting ...


  • Quantitative application for OP/carbamate screen

    I. PURPOSE - The purpose of this document is to detail the standard operating procedure for the screening of cholinesterase inhibiting carbamate insecticides in fruits, vegetables, and feeds using the SDI Food Prep Kit and InQuest OP/Carbamate Screening Kit. NB - This is a screening technique designed to determine presence or absence of cholinesterase inhibiting ...


  • Toxicity Identification Evaluation (TIE) as a Tool for Water Quality Management

    Whole effluent toxicity (WET) testing has evolved into a critical element of many National Pollutant Discharge Elimination System (NPDES) permits issued to both industrial and municipal dischargers. Over 6,500 dischargers to both fresh and salt waters are required to conduct toxicity tests to determine if their effluent might be potentially toxic to organisms in the receiving system. While ...


    By AECOM

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