laboratory reagent Articles

Quick and easy distillation & determination of total SO2 in foods and beverages

Sulfur-containing compounds, such as sulfur dioxide and sulfites, are widely used as preservatives and anti-oxidants in foods and beverages. Exposure to high levels of sulfites can cause an allergic reaction, difficulty breathing, sneezing, throat swelling, hives and migraine headaches. Given the health risks associated with sulfite exposure, the amount of sulfites in beverages and foodstuffs is ...

Jan. 3, 2018

By BÜCHI Labortechnik AG
Delamanid(OPC-67683)

Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids, cruciala component of the cell wall of the Mycobacterium tuberculosis complex. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. ...

Jun. 11, 2019

By MedChemExpress LLC (MCE)
OICR-9429

OICR-9429 is a novel small-molecule antagonist of the Wdr5-MLL interaction with IC50 of 5 uM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with years ...

Jul. 25, 2019

By MedChemExpress LLC (MCE)
MRT68921

MRT68921 is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support ...

Jul. 12, 2019

By MedChemExpress LLC (MCE)
MRT68921 dihydrochloride

MRT68921 dihydrochloride is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and ...

Jul. 28, 2019

By MedChemExpress LLC (MCE)
CBR-5884

CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with ...

Jun. 6, 2019

By MedChemExpress LLC (MCE)
AZD0156

AZD0156 is an oral, potent and selective ATM inhibitor with an IC50 of 0.58 nM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with years of experience ...

Jun. 17, 2019

By MedChemExpress LLC (MCE)
BAY1125976

BAY1125976 is a selective allosteric Akt1/Akt2 inhibitor, inhibits Akt1 and Akt2 activity with IC50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and ...

Jul. 13, 2019

By MedChemExpress LLC (MCE)
Introducing a New ASTM Method for the Determination of Total Nitrogen, and TKN by Calculation, in Water Samples

The USEPA Clean Water Act (CWA) requires national approval for all methods used for CWA compliance. There are approved methods for the determination of inorganic nitrogen (NO3-N, NO2-N, and NH3-N), and for organic nitrogen (TKN – NH3-N)2. There are no EPA approved methods for the determination of total nitrogen although it is a required parameter in many USEPA permits, including monitoring ...

Apr. 5, 2017

By Shimadzu Scientific Instruments Inc
Branaplam(LMI070,NVS-SM1)

Branaplam (LMI070) is a highly potent, selective and orally active small molecule SMN2 splicing modulator. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support ...

Jul. 17, 2019

By MedChemExpress LLC (MCE)
Mivebresib(ABBV-075)

Mivebresib is a potent and orally available bromodomain and extraterminal domain (BET) bromodomain inhibitor. Mivebresib binds to BRD4 with a Ki of 1.5 nM.MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and ...

Jun. 18, 2019

By MedChemExpress LLC (MCE)
EAI045

EAI045 is an allosteric inhibitor of mutant EGFR with IC50s of 1.9, 0.019, 0.19 and 0.002 μM for EGFR, EGFRL858R, EGFRT790M and EGFRL858R/T790M at 10 μM ATP, respectively.MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has ...

Jun. 5, 2019

By MedChemExpress LLC (MCE)
IPI549

IPI549 is a potent and selective PI3Kγ inhibitor with an IC50 of 16 nM.MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with years of experience in the ...

Aug. 3, 2019

By MedChemExpress LLC (MCE)
Mirogabalin(DS5565)

Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural ...

Jul. 16, 2019

By MedChemExpress LLC (MCE)
Phorbol 12-myristate 13-acetate(PMA)

Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is an activator of SphK through protein kinase C (PKC) activation. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and ...

Jul. 31, 2019

By MedChemExpress LLC (MCE)
Naquotinib(ASP8273)

Naquotinib (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor, with IC50s of 8-33 nM toward EGFR mutants and 230 nM for EGFR. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and ...

May 2, 2019

By MedChemExpress LLC (MCE)
MP-A08

MP-A08 is a highly selective ATP competitive sphingosine kinase (SK) inhibitor that targets both SphK1 and SphK2 with Kivalues of 6.9 ± 0.8 μM and 27 ± 3 μM, respectively. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and ...

Jul. 26, 2019

By MedChemExpress LLC (MCE)
MI-538

MI-538 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams ...

Nov. 21, 2018

By MedChemExpress LLC (MCE)
SKF-96365 hydrochloride

SKF-96365 hydrochloride is a non-selective TRP Channel blocker. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with years of experience in the life ...

Jun. 12, 2019

By MedChemExpress LLC (MCE)
SR-3029

SR-3029 is a potent and ATP competitive CK1δ and CK1ε inhibitor, with IC50s of 44 nM and 260 nM, respectively, and Kis of 97 nM for both kinases. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable ...

May 13, 2019

By MedChemExpress LLC (MCE)

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