laboratory reagent Articles
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Introducing a New ASTM Method for the Determination of Total Nitrogen, and TKN by Calculation, in Water Samples
The USEPA Clean Water Act (CWA) requires national approval for all methods used for CWA compliance. There are approved methods for the determination of inorganic nitrogen (NO3-N, NO2-N, and NH3-N), and for organic nitrogen (TKN – NH3-N)2. There are no EPA approved methods for the determination of total nitrogen although it is a required parameter in many USEPA permits, including monitoring ...
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OICR-9429
OICR-9429 is a novel small-molecule antagonist of the Wdr5-MLL interaction with IC50 of 5 uM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with years ...
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Mivebresib(ABBV-075)
Mivebresib is a potent and orally available bromodomain and extraterminal domain (BET) bromodomain inhibitor. Mivebresib binds to BRD4 with a Ki of 1.5 nM.MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and ...
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IPI549
IPI549 is a potent and selective PI3Kγ inhibitor with an IC50 of 16 nM.MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with years of experience in the ...
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Delamanid(OPC-67683)
Delamanid, a newer mycobacterial cell wall synthesis inhibitor, inhibits the synthesisi of mucolic acids, cruciala component of the cell wall of the Mycobacterium tuberculosis complex. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. ...
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AZD0156
AZD0156 is an oral, potent and selective ATM inhibitor with an IC50 of 0.58 nM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with years of experience ...
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EAI045
EAI045 is an allosteric inhibitor of mutant EGFR with IC50s of 1.9, 0.019, 0.19 and 0.002 μM for EGFR, EGFRL858R, EGFRT790M and EGFRL858R/T790M at 10 μM ATP, respectively.MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has ...
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Phorbol 12-myristate 13-acetate(PMA)
Phorbol 12-myristate 13-acetate (PMA), a phorbol ester, is an activator of SphK through protein kinase C (PKC) activation. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and ...
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Naquotinib(ASP8273)
Naquotinib (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor, with IC50s of 8-33 nM toward EGFR mutants and 230 nM for EGFR. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and ...
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MP-A08
MP-A08 is a highly selective ATP competitive sphingosine kinase (SK) inhibitor that targets both SphK1 and SphK2 with Kivalues of 6.9 ± 0.8 μM and 27 ± 3 μM, respectively. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and ...
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MI-538
MI-538 is an inhibitor of the interaction between menin and MLL fusion proteins with an IC50 of 21 nM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams ...
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SKF-96365 hydrochloride
SKF-96365 hydrochloride is a non-selective TRP Channel blocker. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with years of experience in the life ...
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MRT68921
MRT68921 is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support ...
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MRT68921 dihydrochloride
MRT68921 dihydrochloride is the most potent inhibitor of ULK1 and ULK2, with IC50 values of 2.9 nM and 1.1 nM, respectively. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and ...
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SR-3029
SR-3029 is a potent and ATP competitive CK1δ and CK1ε inhibitor, with IC50s of 44 nM and 260 nM, respectively, and Kis of 97 nM for both kinases. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable ...
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CBR-5884
CBR-5884 is an inhibitor of 3-phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with ...
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KDM5A-IN-1
KDM5A-IN-1 is an inhibitor histone demethylases.MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly customer service and technical support teams with years of experience in the life science industry. ...
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BAY1125976
BAY1125976 is a selective allosteric Akt1/Akt2 inhibitor, inhibits Akt1 and Akt2 activity with IC50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and ...
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Mirogabalin(DS5565)
Mirogabalin (DS-5565) is a novel, preferentially selective α2δ-1 ligand characterized by high potency and selectivity to the α2δ-1 subunit of voltage-sensitive calcium channel complexes in the CNS. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural ...
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Rocaglamide(Rocaglamide A,Roc-A)
Rocaglamide is a potent NF-κB activation inhibitor.Tumor volumes in the Rocaglamide-treated group are 45±12% compared with the control group. MedChemExpress (MCE) offers a wide range of high quality research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. MCE has knowledgeable and friendly ...
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