quadrupole mass spectrometer Articles

  • Mass spectrometers for catalysis & thermal analysis

    Hiden Analytical have been designing and developing the highest quality quadrupole mass spectrometer based gas analysis systems for over 25 years. We have built a reputation for delivering instruments with superior sensitivity, accuracy and reproducibility together with a first class global service and applications support network. From dedicated triple filter UHV TPD quadrupoles to fully ...


    By Hiden Analytical

  • Pumping Ions – An Exercise in Engineering Sensitivity Into the Xevo TQ-XS Mass Spectrometer

    The challenge: Create the most sensitive mass spectrometer for quantitative analysis. That’s a tall order for any design engineering team. When given that assignment for a next-generation, tandem quadrupole mass spectrometer, our design engineers first spoke to those for whom analytical sensitivity means the most: scientists doing quantitative studies for ...


    By Waters Corporation

  • Simon Fraser University Opens Suite of Mass Spectrometers for Natural Products Discovery Research

    As a graduate student at the University of British Columbia, Dr. Roger Linington discovered his future life’s work serendipitously. While studying sponges, it became clear to him that one of the challenges in studying macroorganisms is their limited or slowly replenishing supply. To perform mechanism and mode-of-action studies, he needed a larger, more accessible source of ...


    By Waters Corporation

  • EPA Method 8270D Analysis Using Narrow-bore GC Columns and Fast Data Acquisition with a Quadrupole GCMS System

    Analytical support of environmental programs has been conducted for several decades using standard-bore capillary columns (0.25mmid) and quadrupole GCMS systems. Depending on method conditions and program requirements, the QC measures can consume a significant portion of a 12-hour shift, leaving less time for analysis of real-world samples. Typical cycle times (time from beginning of a run to the ...

  • Tandem Quad Mass Spectrometry: The Foundation of Product Safety, Efficacy, and Decision-making

    There is a rightfully high expectation from consumers that the amounts of compounds and ingredients that producers report in their goods are accurate down to trace levels. Whether personally or professionally, we all rely on this analytical information coming from laboratories that enables critical decisions to be made. Analytical chemists have been performing quantitative studies for ...


    By Waters Corporation

  • Mass Spectrometry Makes Cents for UC San Diego Clinical Laboratory

    “Fast is fine; but accuracy is everything.” The quote is attributed to the famous Wyatt Earp, a sharpshooter and lawman who, with help from his two brothers, sent three outlaws to their graves in the Gunfight at the O.K. Corral in Tombstone, Arizona in 1881. One hundred ...


    By Waters Corporation

  • Growing hydrogen expectations: embedded catalyst design for active and stable catalysts

    Hydrogen as an energy vector in combination with fuel cells is one of the emerging energy solution in terms of sustainability and low environmental impact. H2 sustainable production is therefore one of the key target of today. Recently, the Materials, Environment and Energy research group at the University of Trieste, coordinated by Professor Paolo Fornasiero investigated various options for H2 ...


    By Hiden Analytical

  • Detection of Low Levels of Organic Species in Seawater

    In this particular experiment, the sensitivity of a Hiden Quadrupole Mass Spectrometer (QMS) to dimethylsulphide was measured Dimethylsulphide (DMS) - chemical formula CH3SCH3- is a naturally produced trace substance, evolved from certain marine micro organisms, such as plankton. Detection of fluctuations in the DMS concentration in seawater therefore gives important information about the ...


    By Hiden Analytical

  • High Throughput LC-MS-MS Analysis of Carbendazim in Orange Juice

    Highly sensitive analytical methods are necessary to prevent contaminated produce from entering the food supply. In order to help move fresh imports through customs without delay, methods must be rapid and cost effective, in order to test imports thoroughly. LC-MS offers the highly sensitive, robust measurement needed, while ultra high performance liquid chromatography enables high speed ...

  • Analysis of Haloacetic Acids in Tap Water Using LC/MS/MS

    Haloacetic acids are produced as by-products of chlorination in the water treatment purification process. Three haloacetic acids, monochloroacetic acid (MCAA), dichloroacetic acid (DCAA), and trichloroacetic acid (TCAA), are subject to water quality standard for drinking water with established limits (MCAA: 0.02 mg/L, DCAA: 0.04 mg/L, TCAA: 0.2 mg/L) by Japan Ministry of Health, Labour and ...

  • Tof-HRMS: Rescuing low-exposure bioanalysis applications from chemical noise

    The drug development process requires pharmacokinetic (PK) analysis to be performed as part of safety and efficacy studies in both preclinical species and human subjects. For high-sensitivity bioanalysis, liquid chromatography (LC) coupled to a triple quadrupole mass spectrometer (LC-MS/MS) is considered the gold standard for quantification. However, for some low-exposure applications, ...


    By Waters Corporation

  • Fast analysis of semi-volatile organic compounds using PTV-GC–TOF MS

    The evaluation of semi-volatile organic compounds (SVOCs) in environmental matrices poses many challenges for the analyst, not least the vast number that may be encountered in any given analysis. In addition, analyte reactivity and the potential for multiple analytes to co-elute makes achieving the required method detection limits (LODs or MDLs) quickly and cost-effectively a formidable task ...


    By SepSolve Analytical

  • Gaseous release in LiNH2–MgH2 systems

    Hydrogen is considered a safe and clean alternative to fossil fuels. Hydrogen storage is currently obtained by compressing the gas at high pressure. Researchers are currently attempting to tackle safety and energy density issues by locking hydrogen into solids, packing large quantities into small volumes. However, most of the known solids (i.e. intermetallics) show very low gravimetric density, ...


    By Hiden Analytical

  • Heterogeneous electro-Fenton oxidation of azo dye methyl orange catalyzed by magnetic Fe3O4 nanoparticles

    Azo dye methyl orange (MO) degradation by heterogeneous electro-Fenton (EF) with a magnetic nano-Fe3O4 catalyst was investigated. In this study, Fe3O4 was synthesized by a coprecipitation method and characterized by X-ray diffraction and scanning electron microscopy. The influences of the main operating parameters such as current density, pH, catalyst dosage and ...


    By IWA Publishing

  • 5 Insights: Protein Quantification Using the Surrogate Peptide Method

    Protein quantification for bioanalysis is difficult but you have options. The following insights will bring you up to speed on current challenges, issues, and options. 1. Biopharma is Growing Fast Biopharmaceutical drug development is experiencing rapid growth. More than 600 biologics have U.S. FDA approval and over 50 monoclonal antibodies (mAbs) are approved in the US and EU ...


    By Waters Corporation

  • Detection and measurement of GWGs in semiconductor fab facilities

    Problem Statement Various processes and tools in the modern wafer fab plant produce effluent streams that contain unacceptably high levels of perfluorocarbon GWGs (greenhouse warming gases). These effluent streams are abated by plasma incineration and wet scrubbers and other techniques. It is necessary to measure the destruction removal efficiency (DRE) of the various abatement methods ...


    By CIC Photonics, Inc.

  • Has Your Dinner Menu Been Quantified?

    For decades, food security was viewed exclusively through the lens of shortages. In the 1960s, when daily food availability in emerging countries was just 1,850 kcal per person as many as half of the world’s population was malnourished. It’s easy to understand our narrow focus on increasing food production. The challenges we face have shifted. The development and ...


    By Waters Corporation

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