surface plasmon resonance Articles
Optical humidity sensor based on m-nitroaniline doped gold/poly-vinyl alcohol nano-composite
Gold/polyvinyl alcohol nano-composites with two different concentrations of gold (~1.0 wt% and ~2.0 wt% respectively) were prepared via in-situ reduction of gold salt by employing hydrazine hydrate as a reducing agent. The optical absorption spectra of nanocomposites reveal the shift in the surface plasmon resonance band from 525 nm to 560 nm with increase in gold concentration. The obtained ...
Nanoholes in metals with applications to sensors and spectroscopy
In this paper, we review our experimental and theoretical investigations of nano-holes in metal films. Our first contribution to this field was to demonstrate experimentally that the shape of the holes in arrays could be used to influence the optical properties; in particular, we showed how to control the polarisation with elliptical nano-holes. A theory explaining this shape-effect was presented ...
Surface plasmon resonance biosensors for environmental analysis: general aspects and applications
Interest in the development of Surface Plasmon Resonance (SPR) based biosensors for the detection and monitoring of analytes in several fields has been extensively developed in the last decade. Indeed, SPR-based biosensors demonstrate interesting potential for environmental applications, and a substantial number of studies have been reported for heavy metals, dioxins, pesticides, aromatic ...
Fragment Hit Identification in FBDD
In the field of fragment-based drug discovery (FBDD), biophysical methods such as NMR, native MS, high-concentration biochemical screens (HCS), thermal shift assays (TSA), or surface plasmon resonance (SPR) are usually used as pre-screening techniques to screen fragment libraries to identify the most promising binders. However, employing a subsequent cascade of these methods prior to X-ray ...
Investigation of shell aggregate gold nanostructures
The unique optical properties of noble metal nanostructures have led to an increased interest into their potential uses for various biological applications. For many medical investigations, it would be beneficial to use near infrared (NIR) excitation as well as small gold nanospheres, which can easily reach the cytoplasm and cell nucleus. To fulfil both requirements simultaneously, this paper ...
Aniline chlorination by
in situformed Ag–Cl complexes under simulated solar light irradiation
Ag speciation in a chloride medium was dependent upon the Cl/Ag ratio after releasing into surface water. In this study, the photoreaction of in situ formed Ag–Cl species and their effects on aniline photochlorination were systematically investigated. Our results suggested that formation of chloroaniline was strongly relevant to the Cl/Ag ratio and could be interpreted using the ...
Aptamer-based and DNAzyme-based biosensors for environmental monitoring
Aptamers and DNAzymes are small single-stranded nucleic acids that fold into a well-defined three-dimensional structure with high specificity to various ligands, such as low-molecular-weight organic or inorganic substrates or macromolecules. Their specificity is comparable with and in certain cases even higher than those of antibodies, and they can be applied for specific detection of various ...
A new bisphenol a derivative for estrogen receptor binding studies with surface plasmon resonance
A new bisphenol A (BPA) derivative was synthesized and was immobilized onto the surface of a CM5 sensor chip for the binding study with orphan estrogen‐related receptor (ERRγ) using the surface plasmon resonance (SPR) technique. The kinetic parameters including dissociation and association constants, and, dissociation and association rate constants were investigated. Moreover, a competitive ...
Metallic nanoparticles: synthesis, characterisation and application
Colloidal sphere-like gold nanoparticles were prepared from an HAuCl4 aqueous solution by the chemical reduction method and by using X-ray irradiation, while rod-like gold nanoparticles were synthesised according to the seed-mediated growth method and by sonoelectrochemistry. Gold nanoparticles exhibit fcc structure. Sphere-like gold nanoparticles have a diameter of 20-60 nm, while rod-like gold ...
Syringe Pump Applications In Bioscience & Biochemistry
In an era when biochemical research goes down to a single cell or even a single molecule level, there is a constant demand for ever more precise equipment. Considering that an accurate administration of small amounts of liquid is an imperative in any contemporary biochemical laboratory, the past few decades saw a vivid evolution of syringe pumps, carefully constructed and adapted for targeted ...
By Chemyx Inc
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