tissue homogenization Articles

  • Precellys application focus cancer research oncology - case study

    Cancer research laboratories working with tumor tissues derived from animal models (1,2) or xenografts (3) face difficulties in homogenizing these tough samples using traditional methods (4). The Precellys homogenizers provides high speed sample disruption based on bead- beating technology for the extraction of DNA, RNA, protein, enzymes and metabolites within minutes. It ensures high ...


    By Bertin Instruments SAS

  • Best practices for tough sample grinding in molecular biology using Precellys®

    The biggest challenge when working with fibrous, elastic and tough samples is efficient sample processing. The presence of elastic tissue, calcium phosphate (a rock-hard mineral) and other minerals can develop into a solid and tough matrix which can sometimes be difficult to homogenize. Moreover, heat generation inside the lysing kit tubes during the process results in degradation and ...


    By Bertin Instruments SAS

  • Analysis of biogenic amines food and physiological samples

    Histamine and other polyamines such as Putrescine, Cadaverine, Spermidine and Spermine are products of decomposition. The level of histamine, in particular, has been used as a regulatory guideline for degree of decomposition in fish. Also, Histamine and Tyramine levels are of interest to producers of wine and cheese. The polyamines, Spermidine, Spermine and Putrescine are elevated in neoplastic ...

  • Size-related trace metal bioaccumulation in Asiatic clams (Corbicula fluminea) from the Rio de la Plata estuary, Argentina

    Asiatic clams from the Rio de la Plata estuary were classified in seven Shell Length (SL) classes (6.0 ≤ SL ≤ 41.0 mm) and analysed for metals to evaluate their bioaccumulation dynamics and characterise the significance of growth-related variability potentially interfering in clam monitoring programmes. Metal concentrations were rather homogeneous (Zn: 223 ± 64; Fe: 222 ± 87; Cu: 29 ± 5.5; Mn: 20 ...


    By Inderscience Publishers

  • Proof of concept for the use of macroinvertebrates as indicators of PCB contamination in Lake Hartwell

    The U.S. Environmental Protection Agency (EPA) develops methods and tools for evaluating risk management strategies for sediments contaminated with polychlorinated biphenyls (PCBs), polycyclic aromatic hydrocarbons (PAHs), and other legacy pollutants. Monitored natural recovery (MNR) is a risk management alternative that relies on existing physical, chemical, and biological processes to ...


    By John Wiley & Sons, Ltd.

  • Chemical and biochemical characterization and in vivo safety evaluation of pharmaceuticals in drinking water

    The water constituents that are currently subject to legal control are only a small fraction of the vast number of chemical substances and microorganisms that may occur in both the environment and in water resources. The main objective of this work is to study the health impact resulting from exposure to a mixture of pharmaceuticals that have been detected in tap water at low doses. Analysis ...


    By John Wiley & Sons, Ltd.

  • Precellys application focus forensic - case study

    Forensic laboratories working with hard samples such as hair [1, 2J, bone [3], teeth, skin, etc. experience difficulties with DNA extraction due to the high energy needed to grind these tissues. Moreover, biological evidence is available in small quantities and the current techniques used do not provide high quality results. The Precellys homogenizers provides high speed sample disruption based ...


    By Bertin Instruments SAS

  • TopAir’s Weighing Station

    TopAir is the flagship brand of Statitech Ltd., an ISO 9002 certified manufacturer of cleanroom products for the electronic, semi-conductor, biomedical and defense industries. Established in 1999 and ISO-9002 certified, Statitech Ltd. specializes in the development, production and marketing of a wide variety of standard and custom-made cleanroom products including a weighing station, and has ...


    By TopAir Systems

  • Energy from waste: the recycling of limed fleshings

    Leather products have been around a long while - there are those who claim that it is the second oldest business in the world. Going back a few millennia, when our earliest ancestors decided that sitting on hard rock was not a soft option, they turned to other materials in order to create more comfortable seating, as well as warmer bedding and improved clothing. Animal skins became the fabric ...


    By Flottweg SE

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