toxicology laboratory system Articles

  • Toxicological and Environmental Safety Data - Case Study

    Introduction AGRAGEL is a cross-linked copolymer of acrylic acid and acrylamide partially neutralized as potassium/ ammonium salt. The polymer is in its dry form a granulate and forms a gel-like material upon addition of water or aqueous solutions. Due to the cross-linking it is insoluble in water. Uptake of water is facilitated mainly by the negative carboxylic groups of the polymer and ...

  • A toxicological approach to hazard assessment of carbon nanotubes: implications for workers' health protection

    Since Carbon Nanotubes (CNT) have been only recently introduced into the market, clinical and epidemiological evidence for establishing whether these can affect the cardiovascular system or can exacerbate certain pre-existing medical conditions is lacking. In vitro tests assessing the Quantitative Structure-Activity Relationship (QSAR) may help to identify the hazardous properties, whereas in ...


    By Inderscience Publishers

  • A new approach for the laboratory culture of the fathead minnow, Pimephales promelas

    Fathead minnows are routinely cultured for use in aquatic toxicology studies. A new mass culture system described in the present study consisted of 6 stainless steel tanks, each containing 68 fish and 20 spawning substrates. Spawning results are compared with a previous system of 22 individual glass aquaria, which contained 16 fish and 4 spawning substrates per tank. During a 19‐mo period, the ...


    By John Wiley & Sons, Ltd.

  • METH: THE NEW MOLD - New Markets in Clandestine Laboratory Clean-up

    Untitled Document Intro Clandestine labs have become prevalent across America. They are used for the ...


    By EMSL Analytical, Inc.

  • Mass Spectrometry Makes Cents for UC San Diego Clinical Laboratory

    “Fast is fine; but accuracy is everything.” The quote is attributed to the famous Wyatt Earp, a sharpshooter and lawman who, with help from his two brothers, sent three outlaws to their graves in the Gunfight at the O.K. Corral in Tombstone, Arizona in 1881. One hundred ...


    By Waters Corporation

  • Application of an optimized system for the well-defined exposure of human lung cells to trichloramine and indoor pool air

    In this study an in vitro exposure test to investigate toxicological effects of the volatile disinfection by-product trichloramine and of real indoor pool air was established. For this purpose a set-up to generate a well-defined, clean gas stream of trichloramine was combined with biotests. Human alveolar epithelial lung cells of the cell line A-549 were exposed in a CULTEX® device with ...


    By IWA Publishing

  • China in Talks to Join the OECD System for the Mutual Acceptance of Data in Assessment of Chemicals

    It has recently been reported that China is in discussions with the Organization for Economic Cooperation and Development (OECD) to become a provisional adherent to the Mutual Acceptance of Data (MAD) system. This would require China to accept data from safety testing of chemicals from participating countries generated under the MAD conditions and to establish a Good Laboratory Practice (GLP) ...


    By Bergeson & Campbell, P.C.

  • Cytec Case Study

    Cytec Industries is one of the world's leading specialty chemicals and materials companies with sales, laboratory and manufacturing locations in over 35 countries worldwide. Cytec has made safety and environment two of its top core values. The company strives to be an industry leader in setting the pace in procedures, programs, and most importantly, performance relating to safety, health, and the ...


    By UL The WERCS

  • Invitation to opening day for the NILU Health Effects Lab

    The NILU Health Effects Group would like to invite you to the grand opening of the new laboratories at NILU, Kjeller.   Date: Wednesday, April 22 Time: 10.00- 14.00 Place: Auditorium (ground floor) Health effect lab (1st floor, rooms L-165B) Microscope rooms (1st floor, room L-165A) ...

  • Interactions between mercury and phytoplankton: Speciation, bioavailability and internal handling

    In the present review, key interactions between Hg and phytoplankton are described and discussed in order to highlight the role of phytoplankton in the biogeochemical cycle of Hg and to understand direct or indirect Hg effects on them. Phytoplankton are exposed to various Hg species in surface waters. By Hg uptake, phytoplankton affect the concentration, speciation and fate of mercury in ...


    By John Wiley & Sons, Ltd.

  • Making EH&S compliance a priority throughout the chemical lifecycle

    In the past, environmental, health and safety (EH&S) compliance performance and/or enterprise risk management programs have been geared toward delivering continuous improvement and/or reducing risk with a compartmentalized approach. The safety department tended to workplace safety issues, the transportation department ensured the safe and compliant movement of regulated materials, and the ...


    By 3E Company

  • Fast and reliable analysis of wastewater and sludges with a scanning array ICP emission spectrometer

    Wastewater and sludge analyses generally require the determination of many elements and are economically performed using ICP-OES, due to the speed and robustness of this technique. Several ICP-OES methods are available for this determination including EPA method 200.7 (1). In the USA, DIN 38 406 E22 (2) in Germany, or ISO 11885 (3) on a global scale. For this type of application, the ...


    By PerkinElmer, Inc.

  • Genotoxicity & Environmental Pollution

     The Comet assay is playing an increasing role in studies to determine possible links between environmental pollutants and DNA integrity. The assay is an ideal biomarker for such investigations due to its sensitivity and reliability in detecting DNA damage and repair. Many research groups use our Comet ...


    By Perceptive Instruments Ltd.

  • Case study - Cytec seamlessly migrates 60 years of critical data; enhances product stewardship

    The Situation Cytec Industries is one of the world’s leading specialty chemicals and materials companies with sales, laboratory and manufacturing locations in over 35 countries worldwide. Cytec has made safety and environment two of its top core values. The company strives to be an industry leader in setting the pace in procedures, programs, and most importantly, performance ...


    By UL The WERCS

  • Health Effects of PCBs

    Many studies have been performed in order to know the effects of PCBs on human health. Some of these studies suggest that PCBs are a possible factor in the appearance of cancer in humans who have been in contact with the substance, while they have already been demonstrated to cause a variety of adverse health effects and have been shown to cause cancer in animals. ...

  • Endocrine Disruptors

    Overview: Substances that mimic, influence, or interfere with the body's endocrine system at certain doses, and produce potentially adverse developmental, reproductive, neurological, and/or immune effects in both humans and wildlife, are called endocrine disruptors. These substances can be naturally-occurring or man-made. Endocrine issues have long been the subject of intense ...


    By Bergeson & Campbell, P.C.

  • The Safety of Genetically Modified Foods Produced through Biotechnology

    Executive Summary The Society of Toxicology (SOT) is committed to protecting and enhancing human, animal, and environmental health through the sound application of the fundamental principles of the science of toxicology. It is with this goal in mind that the SOT defines here its current consensus position on the safety of foods produced through biotechnology ...


    By Oxford University Press

  • Whole Effluent Toxicity Testing

    What is Whole Effluent Toxicity (WET) testing? Whole Effluent Toxicity (WET) testing is an important component of the U.S. Environmental Protection Agency’s (USEPA’s) integrated approach for detecting and addressing toxicity in surface waters. The National Pollutant Discharge  Elimination System (NPDES) permit program, authorized by the Clean Water Act, controls water pollution by ...

  • Comparative Risk Assessment

    ' Comparative risk assessment provides a systematic way to compare environmental problems that pose different types and degrees of health risk. It combines information on the inherent hazards of pollutants, exposure levels and population characteristics to predict the resulting health effects. Using data from available sources, rapid, inexpensive comparative risk assessments can identify the most ...


    By The World Bank

  • Toxicity Identification Evaluation (TIE) as a Tool for Water Quality Management

    Whole effluent toxicity (WET) testing has evolved into a critical element of many National Pollutant Discharge Elimination System (NPDES) permits issued to both industrial and municipal dischargers. Over 6,500 dischargers to both fresh and salt waters are required to conduct toxicity tests to determine if their effluent might be potentially toxic to organisms in the receiving system. While ...


    By AECOM

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