toxicology study Articles

  • Zebrafish as a model system to study toxicology

    Monitoring and assessing the effects of contaminants in the aquatic eco‐environment is critical in protecting human health and the environment. The zebrafish has been widely used as a prominent model organism in different fields because of its small size, low cost, diverse adaptability, short breeding cycle, high fecundity, and transparent embryos. Recent studies have demonstrated that ...


    By John Wiley & Sons, Ltd.

  • Toxicological and Environmental Safety Data - Case Study

    Introduction AGRAGEL is a cross-linked copolymer of acrylic acid and acrylamide partially neutralized as potassium/ ammonium salt. The polymer is in its dry form a granulate and forms a gel-like material upon addition of water or aqueous solutions. Due to the cross-linking it is insoluble in water. Uptake of water is facilitated mainly by the negative carboxylic groups of the polymer and ...

  • Toxicological and biological effects of nanomaterials

    In this paper, we summarise the most recent findings on the toxicological and biological (including both favourable and adverse) effects of some studied nanomaterials (nanotubes, fullerene, metallofullerenes, their derivatives, and metallic nanoparticles). The dose-dependent, nanosize dependent, nano-structure dependent biological activity in particular nanotoxicity are discussed. Results show ...


    By Inderscience Publishers

  • Reproductive toxicology in occupational settings: an update

    Objective: This article mainly attempts to review the recent human literature on the adverse effects of occupational factors on fertility, developmental effects and genetic changes in the germ line, which lead to genetic malformations or to genetic disease. The secondary study aim is to answer whether occupational exposures are quantitative momentously for 15% involuntarily childless couples, ...


    By Springer

  • Statistical reporting deficiencies in environmental toxicology

    Null hypothesis significance testing is one of the most widely used forms of statistical testing in environmental toxicology. In this short communication, the authors show that the reporting of statistical information when using null hypothesis significance testing is frequently inadequate in environmental toxicology research. The authors demonstrate this by analyzing the statistical ...


    By John Wiley & Sons, Ltd.

  • Toxicological risks to humans of toxaphene residues in fish

    A revised risk assessment for toxaphene was developed, based on the assumption that fish consumers are only exposed to toxaphene residues that differ substantially from technical toxaphene due to environmental degradation and metabolism. In vitro studies confirmed that both technical toxaphene and degraded toxaphene inhibit gap junctional intercellular communication that correlates with the ...


    By John Wiley & Sons, Ltd.

  • Review of toxicological effects caused by episodic stressor exposure

    Water quality monitoring tools that rely on data from stress‐response tests with continuous exposure at constant concentrations are not always appropriately protective when stressor exposure in the field is episodic in nature. The present study identifies various approaches that have attempted to account for episodic stressor exposure, describes the development of a toxicological effects database ...


    By John Wiley & Sons, Ltd.

  • Cytec Case Study

    Cytec Industries is one of the world's leading specialty chemicals and materials companies with sales, laboratory and manufacturing locations in over 35 countries worldwide. Cytec has made safety and environment two of its top core values. The company strives to be an industry leader in setting the pace in procedures, programs, and most importantly, performance relating to safety, health, and the ...


    By UL - The WERCS

  • Hormesis: Why it is Important to Toxicology and Toxicologists - Critical Review

    This article provides a comprehensive review of hormesis, a dose–response concept that is characterized by a low-dose stimulation and a high-dose inhibition. The article traces the historical foundations of hormesis, its quantitative features and mechanistic foundations, and its risk assessment implications. The article indicates that the hormetic dose response is the most fundamental dose ...

  • Toxicological and ecotoxicological risk‐based prioritization of pharmaceuticals in the natural environment

    Approximately 1500 active pharmaceutical ingredients are currently in use; however, the environmental occurrence and impacts of only a small proportion of these have been investigated. Recognizing that it would be impractical to monitor and assess all pharmaceuticals that are in use, several previous studies have proposed the use of prioritization approaches to identify substances of most ...


    By John Wiley & Sons, Ltd.

  • Selecting the best design for non‐standard toxicology experiments

    Although many experiments in environmental toxicology use standard statistical experimental designs, there are situations that arise where no such standard design is natural or applicable due to logistical constraints. For example, the layout of a lab may suggest that each shelf serve as a block with the number of experimental units per shelf either greater than or less than the number of ...


    By John Wiley & Sons, Ltd.

  • Particle and Fibre Toxicology Publishes Article Concerning Workplace Exposure to CNTs

    On October 21, 2013, Particle and Fibre Toxicology posted an article entitled “Carbon nanotube dosimetry: from workplace exposure assessment to inhalation toxicology.” The authors, who are affiliated with the National Institute for Occupational Safety and Health (NIOSH), note that there are currently no ...


    By Bergeson & Campbell, P.C.

  • Risk Assessment/Toxicology Promotes Health and Welfare of Humans and Ecosystems

    Hundreds of regulations protecting the health and welfare of humans and ecosystems impact industrial and legal firms every day. Commonly, these regulations are associated with protecting human health and the environment from risks associated with site cleanup and closure or remediation projects. Other major health risk regulations are derived from Natural Resources Damage Assessment (NRDA), ...


    By AECOM

  • A toxicological approach to hazard assessment of carbon nanotubes: implications for workers' health protection

    Since Carbon Nanotubes (CNT) have been only recently introduced into the market, clinical and epidemiological evidence for establishing whether these can affect the cardiovascular system or can exacerbate certain pre-existing medical conditions is lacking. In vitro tests assessing the Quantitative Structure-Activity Relationship (QSAR) may help to identify the hazardous properties, whereas in ...


    By Inderscience Publishers

  • Toxicological implications of microcystins on zebrafish embryos in the presence of other environmental pollutants

    Microcystins (MCs) interact with environmental contaminants as well as various other congeners of the MCs family in the natural environment and with antioxidants in the exposed organisms. These interactions are likely to modify the toxicological behavior of MCs at the cellular level. The present study was conducted to understand the toxicological response of extracellular MCs in aquatic systems ...


    By John Wiley & Sons, Ltd.

  • Potentiating toxicological interaction of single‐walled carbon nanotubes with dissolved metals

    The present study explores the ecotoxicology of single‐walled carbon nanotubes (SWCNTs) and their likely interaction with dissolved metals, with a focus on the effect of in vivo exposure in marine mussels. Any nano‐scale effects were negated by the tendency of uncoated SWCNTs to agglomerate in water, particularly with high ionic strength as is the case in estuarine and full strength seawater. ...


    By John Wiley & Sons, Ltd.

  • A NEW MEDIUM FOR CAENORHABDITIS ELEGANS TOXICOLOGY AND NANOTOXICOLOGY STUDIES, DESIGNED TO BETTER REFLECT NATURAL SOIL SOLUTION CONDITIONS

    A new toxicity test medium for C. elegans is presented. The test solution is designed so that it provides a better representation of natural soil pore water conditions than currently available test media. The medium has a composition that can readily be modified to allow for studies of the influences of a range of environmentally relevant parameters on nematode biology and toxicology. Tests ...


    By John Wiley & Sons, Ltd.

  • Toxicity Testing Moves Ahead - Case study

    Lynn L. Bergeson, “toxicity testing moves ahead,” chemical processing, September 2010. The Tox21 Partnership aims for far faster and less expensive screening. Who would have thought that an automated laboratory working around the clock could screen chemical substances for interactions with biological targets at speeds mere mortals could hardly consider — let alone match? Well, ...


    By Bergeson & Campbell, P.C.

  • Precellys application focus forensic - case study

    Forensic laboratories working with hard samples such as hair [1, 2J, bone [3], teeth, skin, etc. experience difficulties with DNA extraction due to the high energy needed to grind these tissues. Moreover, biological evidence is available in small quantities and the current techniques used do not provide high quality results. The Precellys homogenizers provides high speed sample disruption based ...


    By Bertin Instruments SAS

  • Scientometric analysis of Latin American environmental studies

    The objective analysis of scientific production is analysed by scientometric methods that measure the development and progress in science through the analysis of productivity and impact of the scientific production in different universities, countries, research groups, etc. In this context, the aim of present study was to analyse scientific literature in the field of environmental studies that ...


    By Inderscience Publishers

Need help finding the right suppliers? Try XPRT Sourcing. Let the XPRTs do the work for you