Keywords: molecular imprinting, synthetic receptor, thin films, surface wetting, molecular recognition, nanostructures, NSOM, nanotechnology, nanofilaments, nanomoulding, nanoporous surfaces, biosensors, biochips
Nanostructured molecularly imprinted polymer films as synthetic recognition layers
Hierarchically nanostructured materials that combine two or more levels of structure and exhibit a combination of useful features have gained considerable interest. We describe the generation of surface-bound nanofilaments by nanomoulding on a nanoporous template surface that carry at the same time molecularly imprinted binding sites. Fluorescein was used as a model template for imprinting. The surfaces exhibited specific binding of fluorescein as revealed by fluorescence microscopy. Contact angle and ESEM measurements revealed that surface wetting properties are fine-tunable depending on the polymer and on the nanostructuring. We believe that these materials can potentially be very useful for applications such as biosensors and biochips.