The filtration and separation of biological particles has been estimated as 40% of the cost in the manufacture of pharmaceuticals. Liquid chromatography that is the principal method for separating biological particles uses a permanent phase of ultrafine adsorbent particles such as porous silica or resin spheres with particle sizes down to about 1 micron. Speed and resolution are two competing performance factors in conventional chromatography using porous media. One feature is often achieved by sacrificing the other. Conventional wisdom focuses on surface area as the defining element for “dynamic capacity” when determining product throughput employing conventional chromatographic media.
Nano alumina media – An electropositive fibrous media has been developed for water filtration that is capable of retaining sub-micron particles at high flow rates. The active component in the filter media is a nano alumina fiber, only 2 nm in diameter and about 250-300 nm long that are attached to a microglass fiber. Figure 1 shows the nanofibers that appear as fuzz on the microglass. The nanoalumina is aluminum oxide monohydrate (AlOOH), also known as the pseudoboehmite.
Last month, we described the considerations associated with predicting filter service life and how total throughput can be estimated through experimentation. In this second installment, we will examine four filter selection strategies for maximizing service life in continuous-use applications. These aspects consider chemical compatibility, temperature, binding characteristics, and pore size.
At the most basic level, selecting filters that are compatible with the application’s chemistry is the key to...
When renovating the filters the waterworks was interested in testing alternative filter media and replaced the anthracite layer in one of the filters with Filtralite® media for evaluation. Filtralite® is a filter media made of expanded clay and delivered by Saint-Gobain (Weber). In March 2002 Filtralite® media was installed on top of the existing sand in one out of totally 8 filters. This filter was run for nearly a year in parallel to the other filters.
New Media in all filtersThe experiences from...
The effect of sand filter media thickness on the performance of faecal sludge (FS) drying beds was determined in terms of: dewatering time, contaminant load removal efficiency, solids generation rate, nutrient content and helminth eggs viability in the dried sludge. A mixture of ventilated improved pit latrine sludge and septage in the ratio 1:2 was dewatered using three pilot-scale sludge drying beds with sand media thicknesses of 150, 250 and 350 mm. Five dewatering cycles were conducted and monitored for each...
The impact of flow rate and turbidity on the performance of multi-media filtration has been studied using an artificial neural network (ANN) based model. The ANN model was developed and tested based on experimental data collected from a pilot scale multi-media filter system. Several ANN models were tested, and the best results with the lowest errors were achieved with two hidden layers and five neurons per layer. To examine the significance and efficiency of the developed ANN model it was compared with a linear...
Dry as well as wet coating techniques were developed to coat glass beads as filter media to remove manganese from water. For dry coating, powdered manganese oxide ore was fixed on the media surface. Wet coating was achieved by depositing synthetic manganese oxides onto the bead surface. The media were characterized by electron microscopy as well as by testing the removal of Mn2+ in a continuous stirred tank reactor. Image analysis of microscopic pictures illustrated that the surface area could partly be coated by...
Customer comments
No comments were found for Non-woven electrostatic media for chromatographic separation of biological particles. Be the first to comment!
