The efficacy of pressurized solvent extraction with BUCHI's new SpeedExtractor was examined for the extraction of dioxins/furans (PCDDs/PCDFs), polybrominated diphenyl ethers (PBDEs), and perfluorinated compounds (PFCs) from different environmental matrices: PCDDs/PCDFs from soil samples, PFCs from soil and sewage sludge, and PBDEs from lake sediments. The results of the extraction of PCDDs/PCDFs and PFCs were compared to the results obtained with the Dionex Accelerated Solvent Extractor (ASE) and show very similar results. The isolation of PBDEs was performed with certified sediments from the Netherlands Institute for Fishery Research (RIVO). High recovery rates were found from the extraction of PBDEs of the certified sediment. Based on these results, there is strong evidence for the equivalence of both PFE instruments with respect to the extraction of several POPs from environmental solid matrices.