Current research on groundwater vulnerability is aimed mainly at groundwater pollution vulnerability (GPV), and the vulnerability of groundwater quantity is seldom considered. It is important to carry out the groundwater vulnerability evaluation for the management of groundwater resources. This paper presents evaluation models and methods for assessing groundwater quantity and pollution vulnerability. The models and methods were used to evaluate the groundwater vulnerability in the plain area of Baotou, Inner Mongolia, China. The groundwater quantity vulnerability was assessed by computing the groundwater recharge rate, and the GPV was evaluated by simulating the migration time for pollutants traveling from ground surface to the aquifer. The research results could provide scientific support for the management of regional groundwater resources, prevention and control of groundwater pollution.