The paper outlines and specifies ‘responsible port innovation’, introducing the development of a methodological and procedural step-by-step plan for the implementation and evaluation of (responsible) innovations. Subsequently, it uses this as a guideline for the analysis and evaluation of two case-studies. The construction of the Rotterdam Maasvlakte 2 Port meets most of the formulated requirements, though making values more explicit and treating it as a process right from the start could have benefitted the project. The Dalian Dayao Port could improve its decision-making procedures in several respects, including the introduction of new methods to handle value tensions. Both projects show that public support is crucial in responsible port innovation and that it should be not only a multi-faceted but also a multi-level strategy.