John Wiley & Sons, Ltd.

Review of laboratory‐based terrestrial bioaccumulation assessment approaches for organic chemicals: Current status and future possibilities

0
In the last decade, there has been renewed interest in approaches for the assessment of the bioaccumulation potential of chemicals, principally driven by the need to evaluate large numbers of chemicals as part of new chemical legislation while reducing vertebrate test organism use called for in animal welfare legislation. This renewed interest has inspired research activities and advances in bioaccumulation science for neutral organic chemicals in aquatic environments. In January 2013, ILSI Health and Environmental Sciences Institute convened experts to identify the state of the science and existing shortcomings in terrestrial bioaccumulation assessment of neutral organic chemicals. Potential modifications to existing laboratory methods were identified, including areas where new laboratory approaches and/or test methods could be developed to address terrestrial bioaccumulation. The utility of “non‐ecotoxicity” data (e.g., mammalian laboratory data) was also discussed. The highlights of the workshop discussions are presented along with potential modifications in laboratory approaches and new test guidelines that could be used for assessing the bioaccumulation of chemicals in terrestrial organisms. This article is protected by copyright. All rights reserved

Customer comments

No comments were found for Review of laboratory‐based terrestrial bioaccumulation assessment approaches for organic chemicals: Current status and future possibilities. Be the first to comment!