Sampling guidelines for handheld Raman measurements; what you need to know

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Courtesy of B&W Tek

In recent years. Raman spectroscopy has seen increased adoption as the technique of choice for the rapid identification of materials; especially for raw material identification in the pharmaceutical industry, identification of controlled substances and explosives for security applications, polymer material identification for packaging and plastics recycling, and mineral and gemstone identitication and authentication. This shows a clear indication that there is demand for rapid methods for identification of materials in industry and security inspection. Material testing in the field (understood as anywhere out of the traditional laboratory) is continuing to grow in response to issues of substandard raw materials, product adulteration, and counterfeit ingredients, especially in the pharmaceutical industry where regulations require the testing of all raw materials before use.

The growing implementation of Raman as an identification tool in the market can be attributed to the increased availability of portable and handheld Raman instrumentation and the ease of use of Raman technology.1 Raman spectra can be collected without any sample preparation, directly through a transparent container and provide rich characteristic chemical information of the material. Raman analysis of incoming goods in the warehouse and dispensing areas has proven to be an extremely cost effective and highly traceable procedure to qualify and validate the transit of materials, without the need to have samples sent to an analytical laboratory. As a result, more and more global facilities are expanding their Raman analysis capabilities with portable and handheld Raman devices. Additionally, the capability to take a powerful material characterization tool such as a Raman spectrometer anywhere in the field is expanding the capabilities of researchers to be more productive and efficient when running samples on the go. such as in mineralogy, ait restoration, safety in chemicals plants. firefighters and many other fields.

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