US EPA Method 8270 describes the analysis of a wide variety of semivolatile compounds by GC/MS. In this application, the Equity-5 was used to analyze 74 compounds commonly targeted for analysis by environmental laboratories. The analysis also included 6 internal standards and 8 surrogates. The Equity column showed excellent peak shape and response for both basic and acidic compounds, including the typically low-responding compounds 2,4-dinitrophenol, pentachlorophenol, and benzidine. The low bleed of this column made it suitable for use in an MSD.