In this study papaya seeds were used to remove methylene blue dye from aqueous solution. Papaya seeds were characterized as possessing a macro/mesoporous texture and large pore size. Studies were carried out in batches to evaluate the effect of contact time and pH (2–12) on the removal of dye. It was observed that the adsorption of dye was better in the basic region (pH 12). The equilibrium data were analyzed using Langmuir, Freundlich, Dubinin–Raduschkevich, Tempkin, Jovanovich, Redlich–Peterson, Sips, Toth and Radke–Prausnitz isotherms. The equilibrium data were best described by the Langmuir isotherm with a maximum adsorption capacity of 637.29 mg g–1. Adsorption kinetic data were fitted using the pseudo-first-order and pseudo-second-order model. The adsorption kinetic is very fast and was best described by the pseudo-second-order model.