The site of New Pleurona, a well fortified city of the Hellenistic period, is located in the western part of Greece. Archaeological and geophysical evidence indicates that the city, during its existence, was connected to the sea. The geomorphological changes are linked to the delta's progression of the two neighboring rivers, Acheloos and Evinos. In addition to the city's impressive fortifications, Pleurona had an extensive network of water supply and storage, including one of the most impressive cisterns of the ancient world. The case of Plevrona can be viewed as an example of adapting a city's needs through environmental changes and as a best practice in the use of its water resources.