AlpHa Measurement Solutions
The AlpHa Team develops and manufactures intelligent, analytical sensors and technologies that deliver mission-critical and actionable data for customers focused on water quality, health, and safety applications around the world. The AlpHa Mission: AlpHa develops and manufacturers intelligent, analytical sensors and technologies that deliver mission critical and actionable data for customers focused on water quality, health, and safety applications around the world.
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- Business Type:
- Industry Type:
- Water Monitoring and Testing
- Market Focus:
- Globally (various continents)
- Year Founded:
- $1,000,000 US - $10,000,000 US
ANDalyze offers products for testing water contamination using catalytic DNA technologies. The company has developed a methodology for detecting and quantifying chemical levels based on the recent discovery of the catalytic properties of DNA. This technology and product is a universal platform that offers simple, fast, inexpensive and reliable detection of trace metals and other target chemicals.
Water Testing Innovation
Protecting public health by providing safe drinking water to citizens served by community water systems is and will always be a serious concern of government agencies, public water suppliers and private industry around the world. At ANDalyze we are very aware of these requirements and the need to make the on-site testing of these water supplies easier and more reliable. To accomplish this goal we have developed a completely new way to test water for contaminants that greatly reduces the time, effort, cost and complexity of testing water samples for contaminants such as lead in drinking water. Using DNAzyme technology applied to heavy metals testing in water, ANDalyze has developed a DNA sensor technology that test water samples within 2 minutes giving you results at the push of a button. This breakthrough method enables water testing and reporting to be accomplished in a fraction of the time and cost of traditional heavy metals testing methods, and requires no particular skill set or knowledge of chemistry. We all want access to drinking water that meets acceptable drinking water standards. ANDalyze is meeting that challenge by providing the industry with a tool that speeds the process, dramatically reduces the cost per test, and simplifies the steps needed to assure that the world’s water supplies are safe for drinking and free of harmful contaminants.
One of the most important discoveries in the last decade is that DNA/RNA are not only materials for genetic information storage and transfer, but also catalysts for a variety of biological reactions, and thus called catalytic DNA/RNA, (deoxy)ribozymes, or DNA/RNAzymes. Because metal ions play essential roles in the structure and function of DNAzymes, the study and application of these new metalloenzymes has become a new frontier in bioinorganic chemistry. ANDalyze has created a product for detecting and quantifying heavy metals in water based on the recent discovery of these catalytic properties of DNA, coupled with established nanoparticle reporter technologies. This is how the technology works…
This technology is a universal platform that offers simple, fast, inexpensive and reliable detection of trace metals and other target chemicals. Measuring the metal ions is done through a reaction that occurs when a water sample containing a target metal ion contaminant (such as lead) is introduced to a sensor unit specific for that contaminant. This produces fluorescence (light) in direct correlation to the amount of metal ion present. The amount of light is measured by a fluorimeter. The fluorimeter reading relates directly to the amount of metal contaminant in the water solution. ANDalyze has designed and manufactured a modernized hand held fluorimeter which, in combination with the consumable DNA based sensors can quickly measure water contaminants at the sample site, greatly reducing the time and effort required by current technologies. This advantage creates a cost savings for organizations that are responsible for water testing of public drinking water supplies or industrial water operations.
The core research on which the ANDalyze technology is based was developed in Dr. Yi Lu’s lab at the University of Illinois.