The Baker Company

26 Articles found

The Baker Company Articles

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  • Multiple users in a Biosafety Cabinet compromise containment

    Multiple users in a Biosafety Cabinet compromise containment

    Abstract Biosafety Cabinets (BSCs) are primary containment devices used to help reduce the risk of contamination to the work, the worker, and the surrounding environment. These devices have rigorous testing and certification to ensure their ...

    Kara F. Held;Robert Thibeault

  • Can overcrowding a BSC work area lead to a loss of containment?

    Can overcrowding a BSC work area lead to a loss of containment?

    Abstract Work conducted in Biosafety Cabinets (BSCs) is a common sight in many laboratories worldwide, but some misconceptions about their capabilities sometimes arise. A BSC used for storage of materials or the air grilles or grates blocked is ...

    Kara F. Held;Jacqueline Boudreau

  • Heat sources in a Biosafety Cabinet Compromise Experimental and User Protection

    Heat sources in a Biosafety Cabinet Compromise Experimental and User Protection

    Abstract Keeping a contamination free environment in the laboratory has commonly been achieved by one of two ways: a flame or a biosafety cabinet (BSC). However, it has been frequently observed that the two practices have been combined, where a heat ...

    Kara F. Held;Robert Thibeault;Jacqueline Boudreau

  • Accelerating stem cell knowledge into regenerative medicine by OUH-CELL-BENCH

    Accelerating stem cell knowledge into regenerative medicine by OUH-CELL-BENCH

    One major challenge for implementing stem cell treatment in the clinics, is the interdisciplinary work required by stem cell biologists and medical doctors as well as the state-of-the-art equipment needed at public hospitals to successfully ...

    Eva Bang Harvald;Charlotte Harken Jensen;Søren Sheikh;Ditte C. Andersen

  • The Effectiveness of HEPA Filters on DNA-Poster

    The Effectiveness of HEPA Filters on DNA-Poster

    Abstract Objectives: Most laboratory techniques utilize biosafety cabinets (BSCs) in order to provide contamination control of the experiments. BSCs depend on airflow and HEPA filters to remove aerosols and particulates from the environment. ...

    Kara F. Held;Clark Rundell;Robert Thibeault;Daniel Ghidoni;Daniel Magoon;Trinh Nguyen;Alyson Fisher;Alyson Fisher;Bretna Parker;Tania Spenlinhauer;Joan Gordon;Steven Nesbitt

  • The Effectiveness of HEPA filters on DNA

    The Effectiveness of HEPA filters on DNA

    Abstract Most laboratory techniques utilize biosafety cabinets (BSCs) in order to provide contamination control of the experiments. BSCs depend on airflow and HEPA filters to remove contaminants from the environment. Aerosols may be created ...

    Kara F. Held;Robert Thibeault;Daniel Ghidoni;Clark Rundell;Daniel Magoon;Trinh Nguyen;Alyson Fisher;Bretna Parker;Tania Spenlinhauer;Joan Gordon;Steven Nesbitt

  • Rapid and effective modulation of dissolved oxygen levels in cell culture media for improved hypoxia studies

    Rapid and effective modulation of dissolved oxygen levels in cell culture media for improved hypoxia studies

    Cell-based hypoxia studies are reliant on close control of O2 concentration in the surrounding environment. Exposure to ambient O2 (21%) concentrations for short or sustained periods of time can result In confounding results due to oxygen toxicity. ...

    Param Mohan;Tina P. Dale;Saniya Gupta;Alasdair G. Kay;Nicholas R Forsyth

  • Innovative Technologies Result in a More Sustainable and Energy-Efficient Total Exhaust Biological Safety Cabinet

    Innovative Technologies Result in a More Sustainable and Energy-Efficient Total Exhaust Biological Safety Cabinet

    Abstract Biological safety cabinets (BSCs) provide the primary source of containment for microbiological research. Laboratories that need containment and removal of vapors, mists and particulates will often choose a Class II, Type B2 total exhaust ...

    Robert Lloyd;Daniel Eagleson;Aaron Johnson

  • Pharmacy Isolator Performance Testing

    Pharmacy Isolator Performance Testing

    The Baker Company Compounding Isolators and USP Requirements Abstract The United States Pharmacopeia (USP) has recently released an In-Process Revision to Chapter – Pharmaceutical Compounding – Sterile Preparations.1 The Baker Company ...

    David C. Eagleson;David G. Stuart

  • Volatile Chemicals and Class II Type A2 Recirculated BSCs: How Much is Safe?

    Volatile Chemicals and Class II Type A2 Recirculated BSCs: How Much is Safe?

    Abstract Volatile chemicals, while typically used in a fume hood, may sometimes be used in conjunction with biological experiments which often require the use of a biosafety cabinet (BSC). While a 100% exhausted Class II Type B2 cabinet is most ...

    Kara F. Held;Daniel Ghidoni;Gary Hazard;David Eagleson

  • Total Exhaust Biosafety Cabinet Upgrade at Research Facility Provides Significant Energy Savings

    Total Exhaust Biosafety Cabinet Upgrade at Research Facility Provides Significant Energy Savings

    When Harvard’s Biology Research Infrastructure (BRI) facility opened in 2006, they required four biological safety cabinets to provide primary containment during animal procedures. In the selection process, workspace containment and isolation ...

    Daniel Ghidoni;Peter Brown

  • Increasing Cell Adherence with a Hypoxia Workstation

    Increasing Cell Adherence with a Hypoxia Workstation

    Abstract A major criticism of all-in-one workstations (sometimes known as incubated workstations or incubated glove boxes) over using traditional incubators and biosafety cabinets for cell culture is that the exposure to excessive vibration will ...

    Samir Patel;Garry Taylor;Rachel Steeg;Kara Held

  • Conditioning Media to Target Dissolved Oxygen Levels

    Conditioning Media to Target Dissolved Oxygen Levels

    Summary Hypoxia is defined as oxygen deficiency in cellular environments. Oxygen (O2) deficiency within in vivo environments is commonly linked to a wide range of co-morbidities, e.g., respiratory failure, Mycobacterium tuberculosis infection and ...

    Brian Parent;Victoria Eon

  • Hypoxia Workstation with HEPA-Filtration Option Demonstrates Enhanced Containment to Protect User

    Hypoxia Workstation with HEPA-Filtration Option Demonstrates Enhanced Containment to Protect User

    Abstract Hypoxia workstations are utilized by researchers who require stable and accurate low oxygen environments for their research. Oxygen, carbon dioxide, temperature and humidity are precisely controlled within the work area of the workstation ...

    Bob Lloyd;Samir Patel;Becky Metivier

  • Biological Safety Canopy Exhaust Connection Saves Energy and Improves Overall Safety Performance

    Biological Safety Canopy Exhaust Connection Saves Energy and Improves Overall Safety Performance

    Abstract With environmental resources becoming more and more limited and energy costs on the rise, reducing energy consumption is an important consideration for every laboratory. It is especially important in light of an analysis published by the ...

    Robert Lloyd;Dennis Eagleson;David Eagleson

  • New Animal Transfer Station Offers Improved Containment and Allergen Control

    New Animal Transfer Station Offers Improved Containment and Allergen Control

    When using animals in research, protecting the animal from both the lab environment and cage-to-cage cross-contamination are a researcher’s highest priorities. Today, increased awareness of the potential health hazards presented to laboratory ...

    Chip Hersey;Aaron Johnson;Becky Metivier

  • Energy-Efficient Biological Safety Cabinet Reduces Energy Costs While Ensuring Safety

    Energy-Efficient Biological Safety Cabinet Reduces Energy Costs While Ensuring Safety

    Abstract As the primary containment devices within laboratories, biological safety cabinets (BSCs) are critical to protect personnel, product and environment from exposure to biohazards and cross-contamination during routine daily procedures. ...

    Robert Lloyd;David C. Eagleson;Dennis Eagleson

  • Terminology Changes in the 2002 Revision of NSF 49 NSF/ANSI Standard # 49 – 2002 Class II Biological Safety Cabinets Types

    Terminology Changes in the 2002 Revision of NSF 49 NSF/ANSI Standard # 49 – 2002 Class II Biological Safety Cabinets Types

    Introduction For more than 20 years there has been confusion concerning Class II biological safety cabinet (BSC) terminology. This has lead to problems in understanding just what the types of Class II BSCs are, and how they should be installed and ...

    David G. Stuart;Dennis Eagleson

  • The bio-analog test for field validation of Biosafety Cabinet performance

    The bio-analog test for field validation of Biosafety Cabinet performance

    Abstract In the past, there was no practical means of quantifying the performance of a biological safety cabinet (BSC) in the field. The microbiological test defined by NSF Standard 49 validates performance by using actual organisms, but such a ...

    Jones R. L. Jr.;Ghidoni D.A.;Eagleson D.

  • Continuous-Flow Bypass for Improved Fume Hood Performance

    Continuous-Flow Bypass for Improved Fume Hood Performance

    Abstract The "roll" of air which forms inside a fume hood immediately behind the sash can be a reservoir for contaminants. Air recirculates at that location rather than exiting the hood immediately. So contaminant concentrations may be higher in the ...

    Ghidoni D.A.;Jones R. L. Jr.;Gingras. R.;Schoch R.