chemical toxic effect Articles
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Impact assessment of pollution in some lake water located at and around Thane City of Maharashtra, India: physico-chemical properties and toxic effects of heavy metal content
Most of the fresh water bodies all over the world are getting polluted day by day, which has become a burning issue of present time. Hence their regular monitoring is crucial for the well-being and health of the surrounding population. Therefore in the present investigation, we carried out a systematic study to estimate the physico-chemical parameters and level of toxic heavy metal content in the ...
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International harmonization of models for selecting less toxic chemical alternatives: Effect of regulatory disparities in the US and Europe
The desire to reduce human exposure to toxic chemicals associated with consumer products that are marketed globally demands the creation of comparative toxicity assessment tools that are based on uniform thresholds of acceptable risks and guidelines for materials use across international boundaries. The Toxic Potential Indicator (TPI) is a quantitative model based on European Union (EU) ...
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Criteria for deviation from predictions by the concentration addition model
Loewe's additivity (concentration addition; CA) is a well‐known model for predicting the toxic effects of chemical mixtures under the additivity assumption of toxicity. However, from the perspective of chemical risk assessment/management, it is important to identify chemicals whose toxicities are additive when present concurrently, i.e., it should be established whether there are chemical ...
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Regulatory Developments - ALJ Decision Imposing Large Fine for TSCA Section 8(e) Penalty May Provide New Guidance on What Constitutes Corroborative Information under Section 8(e)
On November 12, 2013, the United States Environmental Protection Agency (EPA) released an Administrative Law Judge (ALJ) decision ordering Respondent Elementis Chromium Inc., f/k/a Elementis Chromium, LP (Elementis or Company), to pay a $2,571,800 civil penalty for violating Section 8(e) and Section 15(3)(B) of the Toxic Substances Control Act (TSCA). The decision is available online. Although ...
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