Author: N. P. Keller; T. M. Hammond; J. W. Bok; M. D. Andrewski; Y. Reyes-Domínguez; C. Scazzocchio
The genus Aspergillus is ideally suited for the investigation of RNA silencing evolution because it includes species that have experienced a variety of RNA silencing gene changes. Our work on this ...
TAC1 (for transcriptional activator of CDR genes) is critical for the upregulation of the ABC transporters CDR1 and CDR2, which mediate azole resistance in Candida albicans. While a wild-type TAC1 ...
Author: Scott C. Dawson; Meredith S. Sagolla; Joel J. Mancuso; David J. Woessner; Susan A. House; Lillian Fritz-Laylin; W. Zacheus Cande
Microtubule depolymerization dynamics in the spindle are regulated by kinesin-13, a nonprocessive kinesin motor protein that depolymerizes microtubules at the plus and minus ends. Here we show that a ...
Author: A. Katrin Hungerbuehler, Peter Philippsen, Amy S. Gladfelter
Cyclin protein behavior has not been systematically investigated in multinucleated cells with asynchronous mitoses. Cyclins are canonical oscillating cell cycle proteins, but it is unclear how ...
Extracellular autoinducingcompounds in the supernatants of microbial cultures were first ecognized for their roles in the induction ofgenetic competence in gram-positive bacteria 17, 94) and in the ...
Extracellular autoinducing compounds in the supernatants of microbial cultures were first recognized for their roles in the induction of genetic competence in gram-positive bacteria (17, 94) and in ...
Author: Iffa Gaffoor, Daren W. Brown, Ron Plattner, Robert H. Proctor, Weihong Qi, Frances Trail
Polyketides are a class of secondary metabolites that exhibit a vast diversity of form and function. In fungi, these compounds are produced by large, multidomain enzymes classified as type I ...
Author: David S. McNabb, Robin Reed, Robert A. Marciniak
A new reporter system has been developed for quantifying gene expression in the yeast Saccharomyces cerevisiae. The system relies on two different reporter genes, Renilla and firefly luciferase, to ...
Iron, copper, and zinc are all essential nutrients. The electron transfer properties of iron and copper are fundamental to processes such as respiration and photosynthesis. Zinc forms the catalytic ...
Author: Regine Kahmann; Philip Müller; Gerhard Weinzierl; Andreas Brachmann; Michael Feldbrügge
In the phytopathogenic fungus Ustilago maydis, pheromone-mediated cell fusion is a prerequisite for the generation of the infectious dikaryon. The pheromone signal elevates transcription of the ...
Author: Jesús Aguirre; Nallely Cano-Domínguez; Karen Álvarez-Delfín; Wilhelm Hansberg
We have proposed that reactive oxygen species (ROS) play essential roles in cell differentiation. Enzymes belonging to the NADPH oxidase (NOX) family produce superoxide in a regulated manner. We have ...
Author: Jacek Gaertig; Dorota Wloga; Krzysztof Rogowski; Neeraj Sharma; Juliette Van Dijk; Carsten Janke; Bernard Eddé; Marie-Hélène Bré; Nicolette Levilliers; Virginie Redeker
Tubulin undergoes glutamylation, a conserved posttranslational modification of poorly understood function. We show here that in the ciliate Tetrahymena, most of the microtubule arrays contain ...
Loss of the protein kinase Sch9p increases both the chronological life span (CLS) and the replicative life span (RLS) of Saccharomyces cerevisiae by mimicking calorie restriction, but the ...
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