Electrophoresis Articles
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Marshall Iron and Metal BOS 200+ - Case Study
Marshall Iron & Metal in the City of Marshall, Michigan, operated as a railroad maintenance yard from 1899 to 1931 and a foundry from 1938 to 1960. Most recently, it served as an auto salvage/metal scrapyard from 1961 to 1996. Excavation and disposal of soil and debris were completed in the fall of 2015. During these activities, light non-aqueous phase liquid (LNAPL) was observed in an ...
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Hybridization-ELISA in the Bioassay of Oligonucleotide Drugs
Introduction of OligonucleotidesOligonucleotide-based therapeutics represent a rapidly advancing field in current drug development. According to their therapeutic mechanisms, oligonucleotide drugs can be categorized into antisense oligonucleotides (ASOs), small interfering RNA (siRNA), microRNA, anti-gene transcription factor inducers, and nucleic acid aptamers. Oligonucleotide sequences ...
By BOC Sciences
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Application of NH3 Gas Analyzer in Stack Flue Gas: New Prospects of Laser Technology
With the continuous upgrading of environmental protection regulations and people’s increasing attention to environmental issues, the demand for air quality monitoring is also increasing. Ammonia (NH3) is an important atmospheric pollutant, mainly derived from agriculture, industry, transportation and other activities. The NH3 concentration in chimney flue gas not only has an important ...
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Drug-to-Antibody Ratio Analysis Methods
Average drug-to-antibody ratio (DAR) and drug load distribution are two vital properties of antibody drug conjugates (ADCs). Over the years, several ADC bioanalytical methods have been developed to better estimate these properties for early development and routine quality control applications. In this article, we provide an overview of the most widely used methods for the detailed analysis of DAR ...
By BOC Sciences
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Six Liquid Chromatography Detectors That Analytical Researchers Should Know
Pharmaceutical analysis is the application of analytical chemistry in pharmacy. It is a "method science" for the research and development of drug quality control. It mainly uses chemical, physical-chemical, or biochemical methods and techniques to study chemical structures that have been clarified. UV-Vis Absorption Detector Ultraviolet-visible detector (UVD) is one of the most widely used ...
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SCION Compass Chromatography Data System CDS Overview
A Chromatography Data System (CDS) plays a pivotal role in instrument control, data processing, report generation and data archiving. It is essential for Chromatographic Analysis, including high-performance liquid chromatography (HPLC), gas chromatography (GC), ion chromatography (IC), supercritical fluid chromatography (SFC), and capillary electrophoresis (CE), ultra-high performance liquid ...
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Molecular Spectroscopy Solutions for Research and Development
What is Molecular Spectroscopy?Molecular Spectroscopy is a subcategory of spectroscopy that studies the interaction of radiation with molecules and extended materials, as opposed to atomic spectroscopy techniques which deal with individual atoms. Samples that absorb (UV-vis spectroscopy), emit (Photoluminescence spectroscopy), or in elastically scatter (Raman spectroscopy) radiation may be ...
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What is Laser Induced Fluorescence?
Laser Induced Fluorescence (LIF) is an optical spectroscopic technique where a sample is excited with a laser, and the fluorescence emitted by the sample is subsequently captured by a photodetector. LIF can be understood as a class of fluorescence spectroscopy where the usual lamp excitation is replaced by a laser source. Whilst lasers are now routinely used as excitation sources in ...
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Edinburgh Instruments Spectroscopy Instrumentation Overview
Edinburgh Instruments is a world-leader in both single photon counting and time-correlated single photon counting (TCSPC) based fluorescence Spectroscopy Instrumentation in addition to Raman Spectroscopy Instrumentation.We are recognised internationally as a company that offers maximum flexibility and exceptional quality in both instrumentation and services. We understand that choosing the right ...
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A New Method for Sample Preparation to Accelerate Mass Spectrometric Analysis
Mass spectrometry is a widely used protein analysis method, but its sample preparation process is complex and time-consuming. Researchers at Ewon University in Japan have recently developed a new method to significantly shorten the preparation time by anion exchange solid phase extraction centrifugal columns. The findings were recently published in Chemical Communications. The benefit of the ...
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Best Laboratory Practices
A laboratory is a workplace that provides a controlled environment to the researchers in order to perform scientific experiments or research. Good laboratory practice (GLP) provides a framework of guidelines to conduct safe research in the laboratory. In order to facilitate compliance to the maximum level, we are more focused on SOPs and maintenance of laboratory equipment. For the proper ...
By Digital GxP
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The Key Quality Attributes of ADC Drugs
Antibody-drug conjugates (ADCs) are conjugates of cytotoxic small-molecule drugs with targeted monoclonal antibodies through a linker. The specificity of antibodies reduces the toxicity of small-molecule drugs and increases the therapeutic window. In the past two years, ADC drugs have made breakthroughs, and several drugs have been approved for marketing. Key quality attributes ADC drugs mainly ...
By BOC Sciences
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Distribution of soluble carbohydrates in grapevine tissues depending on the life cycle – determination by capillary electrophoresis - Case Study
Instrument Capillary electrophoresis system Capel 105-M Company Instituto de Biología Agrícola de Mendoza Industry Agriculture Region Latin America The distribution of soluble carbohydrates affects fruit yield and quality and depends on plant physiology. Thus, sugar analysis in plants is important throughout the entire growth process. Lumex Instruments offered the Institute of ...
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Capillary electrophoresis introduced to the analysis of wine and spirits - Case Study
Instrument Capillary electrophoresis system Capel 105-M Company LEC (Laboratoire Expertises et Conseils) laboratory Industry Wine and spirits Region Europe One of the leading spirit production control companies in France, LEC successfully uses capillary electrophoresis (CE) for the determination of various compounds in wine and spirits with CE system Capel-105M, and managed to replace some ...
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Electrokinetics: it’s in their genes
Work carried out in the Soviet Union 30 years ago by the father-and-son team of Stanislav and Andrei Dukhin now has implications in nanotechnology and microfluidics. Because they don’t delve into the fundamental theories of electrokinetics very often, few analytical chemists instantly recognize the names of Stanislav Dukhin and his son Andrei. Some may vaguely recollect seeing a ...
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Seminar on Capillary Electrophoresis for the determination of inorganic cations and anions in Thailand demonstrates the benefits of CE method
In the beginning of October, Lumex Instruments held the hands-on training on Capillary Electrophoresis (CE) in Thailand for our users and potential clients. This event was organized together with our distributor CE Combination and involved presentation of CE method and demonstration of Lumex Instruments CE system Capel-205. After the theoretical introduction, our chemical engineer performed ...
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Performance and stability of an expanded granular sludge bed reactor modified with zeolite addition subjected to step increases of organic loading rate (OLR) and to organic shock load (OSL)
This paper shows the effect of organic shock loads (OSLs) on the anaerobic digestion (AD) of synthetic swine wastewater using an expanded granular sludge bed (EGSB) reactor modified with zeolite. Two reactors (R1 and R2), each with an effective volume of 3.04 L, were operated for 180 days at a controlled temperature of 30 °C and hydraulic retention time of 12 h. In the case of R2, 120 g of ...
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Continuous treatment of Acid Red B with activated sludge bioaugmented by a yeast Candida tropicalis TL-F1 and microbial community dynamics
Continuous treatment of Acid Red B (ARB) with activated sludge (AS) bioaugmented by an azo-degrading yeast Candida tropicalis TL-F1 under aerobic conditions was investigated in the form of sequencing batch tests. Dynamics of both bacterial and fungal communities were analyzed using polymerase chain reaction followed by denaturing gradient gel electrophoresis (PCR-DGGE) method. The results ...
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Electric treatment for hydrophilic ink deinking
Hydrophilic inks have been widely used due to higher printing speed, competitive cost and being healthy non-organic solvents. However, they cause problems in both product quality and process runnability due to their hydrophilic surface wettability, strong negative surface charge and sub-micron size. Electric treatment was shown to be able to increase the ink sizes from 60 nm to 700 nm through ...
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Membrane fouling reduction in a cost-effective integrated system of microbial fuel cell and membrane bioreactor
Microbial fuel cells (MFC) and membrane bioreactors (MBR) are promising technologies for wastewater treatment. However, both of them have some drawbacks and application limitations. A cost-effective hybrid system (EMBR) integrating MFC with MBR was evaluated in terms of treatment performance and membrane fouling. In this paper, two electric field directions with a membrane module in the ...
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