Genotoxicity Monitoring Services For Monitoring And Testing Available In Canada
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Manufactured by Wavelength Pharmaceuticalsbased in ISRAEL
Technology Transfer. Process Development and Optimization. Enzymatic Process Development. Read more. Highly potent compounds, Steroids and Cytotoxics manufacturing capabilities. Read more. Oligonucleotides. Analytical Methods Development. Synthesis of Impurities and Standards. Potential Genotoxic Impurities Evaluation including High Sensitivity Analytical Methods. Solid State (Polymorphism ...
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Manufactured by Environmental Bio-Detection Products Inc. (EBPI)based in CANADA
In addition to the specific mutagenicity assays provided by EBPI Analytics, a line of general genotoxicity tests are offered. These assays use modified bacteria that have the induction of a SOS DNA response gene coupled to a gene that expresses a measurable colorimetric endpoint. The degree of induction of the SOS response can be quantified by the degree of colour change, and correlates with the ...
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Manufactured by Cambrex Corporationbased in USA
The analytical testing methods used to monitor potency and purity for raw materials, drug substances and drug products are your primary view into the quality of your materials. Cambrex focuses on efficiently developing robust and high- quality analytical methods that deliver reliable results. We have a vast range of capabilities in instrumentation and detectors including high-throughput column ...
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Manufactured by Creative Bioarraybased in USA
Creative Bioarray is committed to providing microsomal stability assay service with high effectivity and reliability to accelerate drug development. We provide microsomal stability assays for all small compounds such as pharmaceuticals, industrial chemicals, and clients' products. Creative Bioarray's microsomal stability assay can be further extended to metabolite profiling and give out more ...
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Manufactured by Environmental Bio-Detection Products Inc. (EBPI)based in CANADA
EBPI Analytics offers a large selection of traditional Ames tests to meet any research requirement. There are multiple options offered for these assays, and clients can choose from different bacterial strains, developed for specific sensitivities to mutation type. We also offer both Salmonella and E. coli test bacteria which allows standardization of our assays to previously established test ...
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Manufactured by SEQENS Groupbased in FRANCE
Seqens is a world leader in pharmaceutical synthesis, capable of providing full CMC support to prepare for phase III clinical trials and drug registration globally in total compliance with the strictest regulatory, quality and EHS ...
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based in UNITED KINGDOM
Our hazard assessments, generally based on in-depth searches of the scientific literature, aim to define the dose-response for all routes of each of a chemical’s toxicological propensities, for example its carcinogenicity, genotoxicity, or ability to disrupt reproduction. We summarise all of the available data in a transparent format, taking into account the needs of our clients ...
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Manufactured by Molecular Biology Resources, Inc.based in USA
MBR offers assay services to investigate the effects of drug compounds on key DNA replication and repair enzymes, such as human DNA polymerase α (alpha), human DNA polymerase β (beta), human DNA polymerase γ (gamma), and HeLa cell extracts (containing replication protein ...
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Manufactured by Gentronix Ltdbased in UNITED KINGDOM
The mouse lymphoma assay is one of the mammalian gene mutation assays available and is frequently utilised in most genotoxicity testing regulatory frameworks. Able to detect point mutations, clastogens, and in some cases aneugens; the mouse lymphoma assay has an advantage compared to the HPRT (the alternative mammalian gene mutation assay) due to its capability to detect a broader spectrum of ...
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Manufactured by Gentronix Ltdbased in UNITED KINGDOM
The in vitro micronucleus test (MNT) is a main-stay of most regulatory genotoxicity testing strategies, and is used to detect in vitro clastogens and aneugens. In this regard it complements the Ames test well, as between the two study types they detect all of the three major classes of genotoxin. Fluorescence In Situ Hybridisation (FISH) can also be conducted to differentiate predominantly ...
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Manufactured by Regis Technologies Inc.based in USA
For over 50 years, Regis has been a premier custom small molecule manufacturer with excellent analytical support services. Regis’ analytical capabilities are now available to customers requiring stand alone pharmaceutical services. Our Analytical Method Development team (AMD) consists of highly skilled analytical chemists talented in developing and validating phase appropriate methods. Let ...
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Manufactured by BIOHIDRICA Biotecnologias del Agua Ltda.based in CHILE
Water Pollution: Assembly and Development of Ecotoxicity and Genotoxicity ...
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Manufactured by BIOHIDRICA Biotecnologias del Agua Ltda.based in CHILE
Tests are performed according national (NCh) or internationals (ISO, USEPA, OECD and ASTM) ...
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Manufactured by BioDetection Systems b.v.based in NETHERLANDS
BDS offers an extensive panel of CALUX reporter assays that allow for identification of more than 30 distinct biological effects that can be evoked by a wide range of compound classes and mixtures. These effects are related to adverse health effects such as endocrine disruption, acute stress, genotoxicity, carcinogenicity, obesity, xenobiotic metabolism and reproductive toxicity. In addition, ...
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based in USA
RATA, RAA, CGA, FAT, Linearity, 40 CFR, Parts 60 and 75 Testing, Predictive Emissions Monitoring (PEMS), Alternative Monitoring Systems (AMS), RICE MACT Testing, Quality Assurance Plans, CEMS Problem Diagnosis, Temporary ...
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based in USA
Have a pharmaceutical product that needs a formal genotoxic and carcinogenic impurity assessment to meet the requirements of ICH M7? The expert toxicologists at Affygility Solutions can assist your ...
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Manufactured by Alfa Chemistrybased in USA
Reproductive Toxicology Laboratory: Reproductive development and genotoxicity studies are important elements in the safety evaluation of new drugs. With a wealth of control data accumulated over the years and a professional and stable research team, Alfa Chemistry's reproductive toxicology laboratory can provide clients with a full range of reproductive and developmental toxicity evaluation tests ...
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Manufactured by Gentronix Ltdbased in UNITED KINGDOM
The Ames test, a bacterial reverse mutation assay, is the most commonly requested genotoxicity study in regulatory testing frameworks and has been in use for decades. The test investigates the ability of test substances to cause specific mutations in Salmonella or E. coli strains that allow them to then grow on selective agar plates. Used to detect DNA reactive mutagens, which have the ...
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Manufactured by Environmental Bio-Detection Products Inc. (EBPI)based in CANADA
Biomedical and environmental regulatory toxicology encompasses the collection, processing, and evaluation of experimental toxicology data to permit educated decisions on protecting and maintaining human and environmental health against harmful effects caused by natural and synthetic chemical substances. To make these types of decisions, a battery of assays need to be performed and professionals ...
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Manufactured by BioDetection Systems b.v.based in NETHERLANDS
We offer various services for the cost-effective detection of contaminants in e.g. food, feed and environmental samples. Contaminants may either be detected by their biological effect using CALUX assays, or by chemical analysis (non dioxin-like PCBs). Our service laboratory is ISO 17025 accredited for analysis of dioxins, furans and dioxin-like compounds, non dioxin-like PCBs and estrogenic ...
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