chromatographic Articles
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Analysis of Polychlorinated Biphenyls in Soil
Polychlorinated biphenyls (PCBs), also known as chlorinated biphenyls, are a class of chlorides formed by the substitution of chlorine for hydrogen atoms in the biphenyl ring. PCB is a synthetic organic compound used in industry as heat carrier, insulating oil and lubricating oil. The wide use of PCBs in industry has caused global environmental pollution problems. Waste from factories that use ...
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Understanding Thermal Desorption: A Comprehensive Guide
Thermal desorption is a powerful technique used in various fields, including environmental science, analytical chemistry, and material science. It involves the process of heating a material to release volatile compounds or contaminants absorbed within it. This technique is widely employed for the analysis, remediation, and purification of solids, liquids, and gases. In this comprehensive guide, ...
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Pharmaceutical Analysis: Unveiling the Power of Chromatographic Techniques
Pharmaceutical analysis is a form of using all chemical, physical, biological, microbial and other means and methods to study the chemical properties of drugs. During the testing process, the stability of the drug itself, biological components and clinical drug use must be considered. With the continuous development of high technology, the rapid analysis and detection technology of modern drugs ...
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Gas Chromatography Applications
SCION Instruments is a leading supplier of instrumentation for a wide range of Gas Chromatography applications and we are dedicated to support the whole multi-stage process of distillation and chemical reactions. We believe that sensitivity, accuracy and reliability are paramount, and this is reflected within our state-of-the-art product range which is suitable for many Gas Chromatography ...
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SCION Compass Chromatography Data System CDS Overview
A Chromatography Data System (CDS) plays a pivotal role in instrument control, data processing, report generation and data archiving. It is essential for Chromatographic Analysis, including high-performance liquid chromatography (HPLC), gas chromatography (GC), ion chromatography (IC), supercritical fluid chromatography (SFC), and capillary electrophoresis (CE), ultra-high performance liquid ...
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High Performance Liquid Chromatography (HPLC) and Pharmaceutical Analysis
High performance liquid chromatography (HPLC) has become an essential technique in pharmaceutical analysis for the separation, identification, and quantification of pharmaceuticals. Due to its high resolution and sensitivity, it is used for testing drug purity, monitoring degradation, studying pharmacokinetics, and examining drug stability. With recent advances in instrumentation, the technique ...
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Application of HPLC Technology in Drug Detection
What is HPLC technology? High performance liquid chromatography (HPLC) is also called "high-speed liquid chromatography", "high-resolution liquid chromatography", "modern column chromatography" and so on. High performance liquid chromatography is an important branch of chromatography. It uses liquid as the mobile phase, and uses a high-pressure injection system to pump single solvents with ...
By BOC Sciences
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5 Benefits of Custom Gas Mixers for Chromatography Calibration
Gas chromatography (GC) is one of the main techniques in separation science. It is used to analyze and quantify the individual constituents of sample mixtures by first vaporizing the sample and injecting it into a column filled with a solid or semi-solid packing media. Different components elute from the column at different rates based on their unique physicochemical properties and their ...
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Application of LC-MS in the Bioassay of Oligonucleotide Drugs
Introduction of oligonucleotide drugs Oligonucleotides are a class of nucleic acid molecules consisting of dozens of nucleotides with short sequences. They mainly inhibit the expression of target proteins through gene silencing so as to achieve the purpose of treating diseases. The world's first antisense nucleic acid drug was approved in 1998, which started the journey of oligonucleotide drug ...
By BOC Sciences
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Celebrating World Laboratory Day at Techcomp
April 23rd marks World Laboratory Day, a day to celebrate laboratories across the globe where scientists conduct valuable research and make new discoveries to improve our everyday lives. Although the origins of world Laboratory Day are still unclear, it gives us a chance to reflect on the great achievements and breakthroughs in scientific research.At Techcomp, we are delighted to celebrate World ...
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The Key Quality Attributes of ADC Drugs
Antibody-drug conjugates (ADCs) are conjugates of cytotoxic small-molecule drugs with targeted monoclonal antibodies through a linker. The specificity of antibodies reduces the toxicity of small-molecule drugs and increases the therapeutic window. In the past two years, ADC drugs have made breakthroughs, and several drugs have been approved for marketing. Key quality attributes ADC drugs mainly ...
By BOC Sciences
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Gas Chromatography Calibration: How to Calibrate GC
Gas chromatography, often abbreviated to GC, is a staple analytical tool in all manner of quality control and research facilities. It is used to detect specific volatile elements in a gas-phase mixture, to quantify the concentration of specific chemicals, and/or to generate a full spectrum of chemical content. This is extremely valuable in a wide range of application bases, from ...
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Common element test methods
1. Infrared absorption spectrometry Analysis principle: absorption of infrared light energy, causing vibration and rotational energy level transition of molecules with dipole moment change Representation of spectrum: relative transmitted light energy varies with transmission light frequency Information provided: the location, intensity and shape of the peaks, and the characteristic vibrational ...
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Leak Detection within Biotechnology Laboratories
Leak checks to analytical laboratory equipment promotes good laboratory practice and preventative maintenance offering a number of benefits including; improvements to analytical performance, minimising troubleshooting, and the prevention of damage to columns and sensitive detectors. Gas leaks can cause significant losses of expensive high-quality gas, shortened trap and purifier lifetimes, ...
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US EPA Method 524.4 using the Teledyne Tekmar Atomx XYZ and Thermo Scientific ISQ 7000 Mass Spectrometry (MS) System Coupled with a Thermo Scientific TRACE 1310 Gas Chromatograph (GC)
Abstract US EPA Method 524.4 was used to determine the concentration of volatile organic compounds (VOCs) in drinking water. The Teledyne Tekmar Atomx XYZ purge and trap (P&T) VOC sample preparation system combined with a Thermo Scientific ISQ 7000 Mass Spectrometry (MS) system coupled with a Thermo Scientific TRACE 1310 Gas Chromatograph (GC) was used to create a working linear (r²) ...
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US EPA Method 524.2 using the Teledyne Tekmar Atomx XYZ and Thermo Scientific ISQ 7000 Mass Spectrometry (MS) System Coupled with a Thermo Scientific TRACE 1310 Gas Chromatograph (GC)
Abstract US EPA Method 524.2 was used to determine the concentration of volatile organic compounds (VOCs) in drinking water. This method is effective at concentrating trace levels of VOCs, however it can also transfer a significant amount of water vapor to the Gas Chromatograph/Mass Spectrometer (GC/MS) due to the four-minute desorb time recommendation. The Teledyne Tekmar Atomx XYZ purge and ...
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Leak Detection in Biotechnology Laboratories
Pharmaceutical and biotechnological companies use gases in a wide range of applications across all stages of the production chain. Pharmaceutical and biotechnological companies use many variants of gas and chemicals – from high purity gases in the laboratory to process gases in production processes such as chemical synthesis, sterilisation gases and gases to ...
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Gases found within pharmaceutical and bioanalytical laboratories
There are a wide variety of gases found within a pharmaceutical or medical laboratory. Many have no taste, colour or smell, which makes it difficult to tell if a gas leak is present. A gas leak from a cylinder or fixed pipe gas system poses a series risk that can cause a potentially fatal incident or hazard within a laboratory environment. The pharmaceutical industry is one of the world’s ...
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Italian Legislative Decree 152/2006 with the Tekmar Atomx XYZ and Thermo Scientific TRACE 1310 GC and ISQ 7000 MS with an Advanced Electron Ionization (AEI) Source
Abstract Italian Legislative Decree 152/2006 was used to determine the concentration of volatile organic compounds (VOCs) in water matrices. The Teledyne Tekmar Atomx XYZ purge and trap (P&T) system along with a Thermo Scientific TRACE 1310 Gas Chromatograph (GC)/ISQ 7000 Mass Spectrometer (MS) with an Advanced Electron Ionization (AEI) Source was used to create a working linear regression ...
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US EPA Method 8260 with the Teledyne Tekmar Atomx XYZ and the Thermo Scientific TRACE 1310 GC and ISQ 7000 MS with Advanced Electron Ionization (AEI) Source
Abstract US EPA Method 8260, in conjunction with Methods 5030 and 5035, was used to determine the concentration of volatile organic compounds (VOCs) in water and soil matrices. For this study, a Teledyne Tekmar Atomx XYZ purge and trap (P&T) system and Thermo Scientific TRACE 1310 Gas Chromatograph (GC)/ISQ 7000 Mass Spectrometer (MS) with Advanced Electron Ionization (AEI) Source was used to ...
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