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Wet Chemistry Applications

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    Laboratory instruments solutions for pharmaceutical industry

    Pharmaceutical analysis guarantees drug safety by providing information on the identity, content, quality, purity, and stability of pharmaceutical products using analytical chemistry. Metrohm offers you a broad range of instruments and applications for quality control and for monitoring and improving drug manufacturing. With myriads of pharmacopeia-compliant analysis methods, we are your qualified partner for all chemical-pharmaceutical analysis issues and analytical method validations. In accordance with international pharmacopeias and various guidelines, Metrohm offers you analysis for active pharmaceutical ingredients (APIs), excipients, impurities, pharmaceutical solutions as well as pharmaceutical starting materials, and finished pharmaceutical products (FPPs). Additionally, we provide numerous wet chemical methods for atline and online process control as well as inline monitoring methods for assuring cost-effective manufacturing processes that satisfy all regulatory demands.

    By Metrohm AG based in Herisau, SWITZERLAND.

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    Monitoring of phenol in water

    The Situation

    A plant located in the eastern United States manufactures phenolic resin for applications in plastics molding. This plant uses well water for cooling its reaction process and then discharges the water into a local creek.

    By Turner Designs Hydrocarbon Instruments, Inc. based in Fresno, CALIFORNIA (USA).

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    EDXRF spectrometers for pharmaceutical industry

    The pharmaceutical industry is one of the most regulated industries. Contaminants in drug products are examined throughout the manufacturing process, since their presence affects drug stability, behaviour and toxicity. Therefore, regulatory bodies such as the European Medicines Agency (EMEA) and the American Food and Drug Administration (FDA) strictly enforce continuous and ongoing analysis of organic or inorganic impurities from raw materials, excipients and Active Pharmaceutical Ingredients (API) through intermediates of drug products and packaging.

    By Xenemetrix Ltd. based in Migdal Haemek, ISRAEL.

  • Wet and dry cooling systems for chemical industry

    Elegant stockings, cheerfully colored paint, and trendy smartphones – you wouldn’t have any of these without modern chemistry. It all started in the eighteenth and nineteenth centuries with the production of sulfuric acid, soda, fertilizers, paint, artificial fibers, and medicine. Today, it has become one of the most innovative and strongest-growing sectors: the chemical industry. Along with basic chemistry, specialized chemistry, and pharmaceuticals, all of this has become the fifth-largest German industrial sector, with production volume of more than 150 billion euros. Without efficient – and above all safe – cooling technology from ENEXIO, advanced chemistry would be unfeasible.

    By ENEXIO Water Technologies GmbH based in Herne, GERMANY.

  • Catalysis

    Hiden's modular CATLAB offers a wide range of experimental tools for catalyst researchers, from rapid dynamic screening to fully automated precise investigations of active surface chemistry & optimisation of catalytic activity. The CATLAB performs analysis using temperature programmed methods such as TPR/TPO/TPD. Pulse chemisorption is also available with the CATLAB-PCS. The integrated QGA mass spectrometer system provides for quantification of the adsorbed/desorbed species. Physical analyses such as metal surface area, catalyst dispersion and surface acidity/basicity are provided. All CATLAB & mass spectrometer sampling wetted surfaces are designed to have the widest possible compatibility for use with aggressive species. Hiden Analytical’s HPR-20 QIC mass spectrometer is available for coupling to existing catalyst reactors with integral analysis software available for TPD/TPR/TPO quantification. A range of specialized connectors & couplings optimise integration with reactor vessel

    By Hiden Analytical Ltd. based in Warrington, UNITED KINGDOM.

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