Agilent Technologies, Inc.

Agilent Technologies` Solutions for Supercritical Fluid Chromatography with Mass Spectrometric Detection Streamline High-Volume Analysis of Complex Compounds


Source: Agilent Technologies, Inc.

SANTA CLARA, Calif -- Agilent Technologies, Inc. (NYSE: A) today announced that all of its LC/MS instruments now include support software for control of supercritical fluid chromatography (SFC/MS). This enhanced capability enables faster separation, orthogonal selectivity to liquid chromatography, and reduced need for organic solvents. Used together, these hardware-software solutions for SFC/MS further streamline the high-volume analysis of complex samples, making them ideal for use in a variety of industries.

Pharmaceutical, food science, lipodomic, metabolomic, environmental and petrochemical laboratories can use SFC/MS to analyze a range of compounds (e.g., chiral, achiral, polar and nonpolar), including closely related compounds in complex matrices. SFC is fully compatible with atmospheric pressure ionization mass spectrometry and hyphenation with MS detection increases peak resolving capacity, resulting in a greater SFC application range.

'The operation of SFC on Agilent's 6400 Series QQQ LC/MS and 6200/6500 TOF/Q-TOF previously required the use of two software platforms,' said Lester Taylor, Agilent's director of LC/MS product marketing. 'Agilent MassHunter software is now capable of controlling the Agilent 1260 Infinity Analytical SFC system. Use of a single software platform enables our customers to benefit from a fully integrated system for instrument control, data acquisition and analysis.'

In addition to its analytical SFC system, Agilent is the only company offering a hybrid SFC/UHPLC system, which enables seamless switching between complementary modes in routine use and makes method development easier and faster. Both the SFC and the SFC/UHPLC system can be interfaced with Agilent LC/MS systems.

Now, reliable instrument control for method development and routine analysis is available with integrated software for SFC/MS. SFC/MS enables fast, high-resolution separation of compounds that cannot easily be separated by LC methods, with limited use of organic solvents.

For more information, please visit Agilent's online resource for extended LC systems workflow solutions. You may also visit Agilent's 2014 ASMS Media Kit to access additional product information and follow the company's full lineup of ASMS conference programming.

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A) is the world's premier measurement company and a technology leader in chemical analysis, life sciences, diagnostics, electronics and communications. The company's 20,600 employees serve customers in more than 100 countries. Agilent had revenues of $6.8 billion in fiscal 2013. Information about Agilent is available at

On Sept. 19, 2013, Agilent announced plans to separate into two publicly traded companies through a tax-free spinoff of its electronic measurement business. The new compan

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