assay News | Environmental XPRT

Nanomaterials and the Comet Assay

The manufacture and use of nanomaterials is increasing dramatically but there are serious concerns about the impact they may have on health and the environment. One specific area of concern is how nanomaterials interact with cellular DNA perhaps causing damage and mutation. The Comet assay is one of several genotoxicity assays being used to measure nanoparticle induced DNA damage. An increasing ...

Oct. 20, 2010

By Perceptive Instruments Ltd.

The Comet Assay and Nutrition

The effects of nutrients on carcinogenesis have become an increasingly important area of scientific research. Investigation of carotenoids and flavonoids, as well as other antioxidants, suggests that they may have anti-carcinogenic properties. The comet assay is an ideal biomarker for investigating the molecular effects of certain nutrients on carcinogenesis. This is due to its sensitivity and ...

Jun. 23, 2010

By Perceptive Instruments Ltd.

The Comet Assay: Nutrition & Health

Last year we highlighted research linking nutritional factors, mutagenicity and carcinogenesis. One invaluable tool for investigations into DNA damage, protection and repair is the Comet Assay (Single Cell Gel Electrophoresis). ...

May 22, 2011

By Perceptive Instruments Ltd.

The Comet Assay and Occupational Exposure

The Comet assay is being used with increasing popularity in biomonitoring studies to determine the level of DNA damage in workers exposed to potentially hazardous chemicals and radiation. The assay is an ideal biomarker for such investigations due to its sensitivity and reliability in detecting DNA damage and repair. A large number of research groups are utilising our ...

Mar. 29, 2011

By Perceptive Instruments Ltd.

nitrate/nitrite assay kit

Contact Angela: reagenllc@gmail.com We have developed a new kit: Nitrate/Nitrite Assay Kit The unique features of the kit are: High sensitivity and low detection limit (0.02 ppm) High reproducibility A rapid (45 minute), robust enzyme-based assay qualitative ...

Dec. 23, 2015

By Reagen LLC

Comet Assay IV v4.3 Released

Perceptive Instruments is proud to announce the release of Comet Assay IV v4.3 (http://www.perceptive.co.uk/cometassay/). The latest version includes a host of important updates that help make performing the comet assay an even smoother process. High resolution live imaging Comet Assay IV is now supplied with a FireWire video camera ...

Jun. 1, 2011

By Perceptive Instruments Ltd.

New comet assay online resource: www.scorecomets.com

Perceptive Instruments Ltd is proud to announce the launch of the new-look one-stop website for the comet assay: www.scorecomets.com. This online resource contains information regarding the comet ...

Dec. 4, 2011

By Perceptive Instruments Ltd.

Comet Assay IV at the forefront of cancer research

Shown below are findings from some recent papers using Comet assay IV (http://www.scorecomets.com) for scoring comet assay slides: Investigations into Xanthohumol, a hop derived prenylated flavonoid found in beer, suggest that it protects against DNA damage induced by a common cooked food mutagen in rat colon mucosa and liver cells [1]. A small clinical ...

Aug. 1, 2010

By Perceptive Instruments Ltd.

USP monograph modernization: Chemical medicines assay by potentiometric titration

USP and Metrohm jointly developed a potentiometric titration method for potassium bicarbonate and potassium carbonate assay. The new method uses autotitration combined with suitable equivalence point detection fulfilling all USP method validation requirements as per USP General Chapter <1225>. Many of the chemical medicine assay procedures are done by manual ...

Nov. 22, 2018

By Metrohm AG

PERKINELMER LAUNCHES NEW ASSAYS FOR DELFIA® XPRESS MATERNAL HEATH SCREENING SYSTEM

- System Now Supports Triple Test In Second Trimester Screening - Furthering PerkinElmer's Commitment to Maternal ...

May 3, 2005

By PerkinElmer, Inc.

Agilent Technologies introduces next-generation fluorescent in situ hybridization assays for molecular analysis

Agilent Technologies Inc. (NYSE: A) today introduced Agilent SureFISH probes, the next generation of fluorescent in situ hybridization (FISH) assays, delivering a comprehensive menu of the industry's highest resolution probes for a wide range of molecular analysis applications. Agilent SureFISH probes deliver dramatically better ...

Mar. 4, 2012

By Agilent Technologies, Inc.

More convenient and more reliable: USP recommends new ion chromatography method for zinc oxide assay

USP has updated the General Chapter <591> «Zinc Determination» monograph to include ion chromatography as the preferred method for measuring zinc oxide. USP 41–NF 36 was developed in partnership with Metrohm and replaces manual titration methods. The new method is approved by the FDA and benefits users with more ease of use and reliability. ...

Sep. 10, 2018

By Metrohm AG

Agilent Technologies and SISCAPA Assay Technologies Provide Complete Solution for Targeted Multiplexed Protein Quantitation to Enhance Customer Workflows

Agilent Technologies Inc. (NYSE: A) and SISCAPA Assay Technologies (SAT) today announced they have signed a non-exclusive agreement to enable SAT to provide an end-to-end solution for multiplexed protein quantitation using a highly automated workflow for SISCAPA LC-mass spectrometry. This solution will combine SAT's ...

May 26, 2014

By Agilent Technologies, Inc.

Agilent Technologies Introduces Two New ScreenTape Assays to Optimize Next-Generation Sequencing Quality Control, Performance, Throughput

Agilent Technologies Inc. (NYSE: A) today introduced two new assays for the 2200 TapeStation system: the RNA ScreenTape and the D1000 ScreenTape assays. Both assays are essential for the quality control of samples in next-generation sequencing (NGS) workflow. They replace Agilent's R6K and D1K ScreenTape assays. ...

Dec. 16, 2013

By Agilent Technologies, Inc.

ArunA Biomedical, Inc. in Athens, GA awarded more than $79,000 for Developmental Neurotox Assay Using Scalable Neurons and Astrocytes in High-Content Imaging

Aruna Biomedical Inc., has been awarded more than $79,000 from the Environmental Protection Agency (EPA) Small Business Innovation Research (SBIR) program to study developmental neurotox assay using scalable neurons and astrocytes in high-content imaging. The objective of this proposed project and the EPA Computational Toxicology program’s goals are aligned in assessing chemicals for ...

Jun. 12, 2013

By US EPA - Environmental Protection Agency

Automated protein sample preparation system achieves quality milestone perfinity workstation generates % CV values under 10 for affinity selection, proteolysis & serum to peptides assay

Shimadzu Scientific Instruments, in collaboration with Perfinity Biosciences, has developed the Perfinity Workstation (patent pending). Utilizing Shimadzu HPLC components in combination with Perfinity optimized columns, the Perfinity Workstation provides users with fast, highly reproducible results through standardized columns and reagents, proprietary software, and an automated workflow that ...

Jun. 5, 2011

By Shimadzu Scientific Instruments Inc

Automated protein sample preparation system achieves quality milestone perfinity workstation generates % CV values under 10 for affinity selection, proteolysis & serum to peptides assay

Shimadzu Scientific Instruments, in collaboration with Perfinity Biosciences, has developed the Perfinity Workstation (patent pending). Utilizing Shimadzu HPLC components in combination with Perfinity optimized columns, the Perfinity Workstation provides users with fast, highly reproducible results through standardized columns and reagents, proprietary software, and an automated workflow that ...

Jun. 5, 2011

By Shimadzu Scientific Instruments Inc

Accuracy of comet measurements in image analysis systems

If you are scoring comets using image analysis, you will want to be confident that the results you are getting are accurate. Comet Assay IV from Perceptive Instruments has a unique scoring method that has been validated both in-house and by many of the world’s leading pharmaceutical organisations and CROs. As part of the JaCVAM initiative to validate the in vivo and in vitro comet ...

May 24, 2010

By Perceptive Instruments Ltd.

Positive feedback from the JEMS 39th Annual Meeting

Perceptive Instruments completed a successful trip to Japan last month, exhibiting at the 39th Annual Meeting of the Japanese Environmental Mutagen Society (JEMS). During the meeting we met many of our Japanese Comet Assay IV users, ...

Dec. 20, 2010

By Perceptive Instruments Ltd.

Kinesis launches TELOS MicroPlate™ – versatile 96-well SPE format for small volume biological fluid samples

Kinesis has launched the new TELOS MicroPlate™, a versatile 96-well plate for the extraction of drug molecules from small volume biological fluid samples. Available as either loose wells or populated plates, the TELOS MicroPlate is available in 5 and 10mg sorbent masses and allows analyte elution in as little as 50µl. The full range of TELOS neo Generic SPE Sorbents (PRP, PCX, WCX, ...

Dec. 3, 2013

By Kinesis Inc

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