genotoxic News

  • Does mercury damage genes?

    Mercury has many uses but its toxic properties are a health concern. A recent analysis explored the effects of mercury exposure on human genes. They identify four possible processes that could lead to genetic damage and suggest that international safety limits may need reviewing. Mercury is versatile and this means it is used in areas ranging from industry to dentistry and from pharmacology to ...

  • Nanomaterials and the Comet Assay

    The manufacture and use of nanomaterials is increasing dramatically but there are serious concerns about the impact they may have on health and the environment. One specific area of concern is how nanomaterials interact with cellular DNA perhaps causing damage and mutation. The Comet assay is one of several genotoxicity assays being used to measure nanoparticle induced DNA damage. An increasing ...


    By Perceptive Instruments Ltd.

  • What`s in your water? Disinfectants create toxic by-products in drinking water and public swimming pools

    Although perhaps the greatest public health achievement of the 20th century was the disinfection of water, a recent study now shows that the chemicals used to purify the water we drink and use in swimming pools react with organic material in the water yielding toxic consequences. University of Illinois geneticist Michael Plewa said that disinfection by-products (DBPs) in water are the unintended ...


    By ScienceDaily

  • EC Scientific Committee Calls for Information on Nano Silica

    The European Commission (EC) Scientific Committee on Consumer Safety (SCCS) has opened a call for information for a scientific opinion on the safety of silica (nano).  The SCCS invites interested parties to submit any relevant information, such as ...


    By Bergeson & Campbell, P.C.

  • Real time in vitro evaluation of the carcinogenic potential of contaminants

    The Genotrace project, combining targeted research and technology transfer, aims at delivering an innovative test to improve the safety of chemical products, drugs, human and animal food and the environment. The project consortium is led by INRA (French National Institute for Agricultural Research) and includes CNRS (French National Center for Scientific Research), the University Toulouse III ...

  • The Comet Assay: Nutrition & Health

    Last year we highlighted research linking nutritional factors, mutagenicity and carcinogenesis. One invaluable tool for investigations into DNA damage, protection and repair is the Comet Assay (Single Cell Gel Electrophoresis). ...


    By Perceptive Instruments Ltd.

  • New Ames tests now available from Cambio

    Distributed in the UK exclusively by Cambio, Xenometrix products include today’s most advanced Ames mutagenicity assays and cytotoxicity screening kits. These have been specially designed to reduce the amount of test compounds and consumables used, and to require less hands-on time. Xenometrix is particularly proud of its excellent pre- and post-sale customer support which allows new ...


    By Cambio Ltd

  • Comet Assay IV at the forefront of cancer research

    Shown below are findings from some recent papers using Comet assay IV (http://www.scorecomets.com) for scoring comet assay slides: Investigations into Xanthohumol, a hop derived prenylated flavonoid found in beer, suggest that it protects against DNA damage induced by a common cooked food mutagen in rat colon mucosa and liver cells [1]. A small clinical ...


    By Perceptive Instruments Ltd.

  • The Comet Assay and Occupational Exposure

    The Comet assay is being used with increasing popularity in biomonitoring studies to determine the level of DNA damage in workers exposed to potentially hazardous chemicals and radiation. The assay is an ideal biomarker for such investigations due to its sensitivity and reliability in detecting DNA damage and repair. A large number of research groups are utilising our ...


    By Perceptive Instruments Ltd.

  • British Crop Production Council challenges Green Alliance`s opposition to glyphosate and GM crops

    Dr Colin Ruscoe, chairman of BCPC, has contacted Keith Taylor, Green MEP for SE England, to challenge the 'Green Alliance of 46 MEPs opposed to renewal of glyphosate licences. The EU Standing Committee on Plants, Animals, Food and Feed continues to be deadlocked over renewal of licences for ...


  • Jane S. Vergnes, Ph.D., DABT joins Bergeson & Campbell, P.C. and The Acta Group

    Bergeson & Campbell, P.C. (B&C) is pleased to announce that Jane S. Vergnes, Ph.D., DABT has joined our team as Senior Toxicologist for B&C and The Acta Group (Acta). Dr. Vergnes has demonstrated outstanding leadership and an agile, multi-disciplinary talent for problem-solving in her 25 years directing global product stewardship and toxicology departments for Ashland, Inc., ...


    By Bergeson & Campbell, P.C.

  • Safety first for pesticides

    The Environment Committee voted on Wednesday on new legislation governing the production, licensing and use of pesticides. MEPs confirmed that certain toxic chemicals will be banned, except where there is a serious danger to plant health. They also argued that the EU should not be divided into three pesticide licensing zones. In addition, Member States will have to meet quantitative targets for ...


    By European Parliament

  • EPA releases alternatives analysis for thermal paper, flame retardant chemicals

    The Environmental Protection Agency has released two alternatives assessments to help companies that want to choose chemicals to substitute for bisphenol A in thermal paper and decabromodiphenyl ether (decaBDE) as a fire retardant for ...


    By Bloomberg BNA

  • Known Negative Impacts of Dental Mercury Surpass Those of Alternatives

    Substituting alternative materials for mercury-based dental fillings has less negative impact on human health and the environment, according to a new report by the ...


  • Positive feedback from the JEMS 39th Annual Meeting

    Perceptive Instruments completed a successful trip to Japan last month, exhibiting at the 39th Annual Meeting of the Japanese Environmental Mutagen Society (JEMS). During the meeting we met many of our Japanese Comet Assay IV users, ...


    By Perceptive Instruments Ltd.

  • Bisphenol A: EFSA consults on assessment of risks to human health

    EFSA is launching a public consultation on its draft assessment of the human health risks posed by exposure to bisphenol A (BPA). The Authority has undertaken a comprehensive review of scientific literature and previous risk assessments from expert bodies on BPA. All stakeholders and interested parties are invited to comment on the document through an online public consultation that runs until ...


    By European Commission

  • DTSC releases revised `Informal Draft` safer consumer products regulations

    On October 31, 2011, the California Department of Toxic Substances Control (DTSC) released an "informal draft" Safer Consumer Products Regulations (SCPR). DTSC proposed these regulations after ten months of meetings following the California Secretary for Environmental Protection's instructions to DTSC to stop working on issuing proposed regulations and instead "take additional time to be ...


    By Acta Group

  • Midwest Soil-Sement awarded the BNQ

    The BNQ (Bureau de normalisation du Québec) has issued two new BNQ Certifications to Midwest Industrial Supply, Inc., for Soil-Sement® Engineered Formula. Soil-Sement Engineered Formula joins Midwest's EnviroKleen®, giving Midwest three separate BNQ Certifications. Accredited by the Standards Council of Canada (SCC), the BNQ Certification provides the users of ...

  • The 2012 LIFE+ projects

    Austria 4 projects (14.5 million) LIFE+ Environment Policy and Governance (1 project – 3.6 million) LIFE-URBANLAKE (Stadt Wien – Magistratsabteilung 45 – Wiener Gewässer): This project intends to define strategies to reduce the vulnerability of the “Alte Donau” from effects of climate ...

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