Showing results for: genotoxicity News
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Does mercury damage genes?
Mercury has many uses but its toxic properties are a health concern. A recent analysis explored the effects of mercury exposure on human genes. They identify four possible processes that could lead to genetic damage and suggest that international safety limits may need reviewing. Mercury is versatile and this means it is used in areas ranging from industry to dentistry and from pharmacology to ...
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EC Scientific Committee Calls for Information on Nano Silica
The European Commission (EC) Scientific Committee on Consumer Safety (SCCS) has opened a call for information for a scientific opinion on the safety of silica (nano). The SCCS invites interested parties to submit any relevant information, such as identification of the type of cosmetic product using silica in nano-structured form and their concentration; protocols of applications; differences in ...
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Public consultation on the SCCS preliminary Opinion on TiO2
The SCCS primary opinion on TiO2 is now open for consultation until 6th February 2023. The Opinion evaluated several grades of TiO2 used in cosmetic products and considers that the current evidence is not sufficient to rule out genotoxicity with the exception of RM09 and RM11. Since SCCS focuses on dermal and oral mucosa exposure due to the expected use of TiO2 in cosmetics (toothpaste and ...
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Nanomaterials and the Comet Assay
The manufacture and use of nanomaterials is increasing dramatically but there are serious concerns about the impact they may have on health and the environment. One specific area of concern is how nanomaterials interact with cellular DNA perhaps causing damage and mutation. The Comet assay is one of several genotoxicity assays being used to measure nanoparticle induced DNA damage. An increasing ...
By Instem Group
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NIOSH Science Blog Reports on Recent Article Concerning Carbon Nanotubes and Nanofibers Used or Produced in U.S. Facilities
On January 5, 2021, the National Institute for Occupational Safety and Health (NIOSH) posted a Science Blog item entitled “Understanding the Broad Class of Carbon Nanotubes and Nanofibers (CNT/F) Used or Produced in U.S. Facilities.” The item summarizes a recently published article in the journal Particle and Fibre Toxicology, “Physicochemical characterization and ...
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The Comet Assay: Nutrition & Health
Last year we highlighted research linking nutritional factors, mutagenicity and carcinogenesis. One invaluable tool for investigations into DNA damage, protection and repair is the Comet Assay (Single Cell Gel Electrophoresis). The growing popularity & acceptance of the assay is evident by the number of peer reviewed papers in the scientific literature. Here we list a ...
By Instem Group
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Real time in vitro evaluation of the carcinogenic potential of contaminants
The Genotrace project, combining targeted research and technology transfer, aims at delivering an innovative test to improve the safety of chemical products, drugs, human and animal food and the environment. The project consortium is led by INRA (French National Institute for Agricultural Research) and includes CNRS (French National Center for Scientific Research), the University Toulouse III ...
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The Comet Assay and Occupational Exposure
The Comet assay is being used with increasing popularity in biomonitoring studies to determine the level of DNA damage in workers exposed to potentially hazardous chemicals and radiation. The assay is an ideal biomarker for such investigations due to its sensitivity and reliability in detecting DNA damage and repair. A large number of research groups are utilising our Comet Assay scoring systems ...
By Instem Group
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New Ames tests now available from Cambio
Distributed in the UK exclusively by Cambio, Xenometrix products include today’s most advanced Ames mutagenicity assays and cytotoxicity screening kits. These have been specially designed to reduce the amount of test compounds and consumables used, and to require less hands-on time. Xenometrix is particularly proud of its excellent pre- and post-sale customer support which allows new ...
By Cambio Ltd
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Oxidation of Methotrexate by Ozone
Ozonator Industries Ltd. is pleased to announce the results of the testing done by the University of Saskatchewan’s Department of Chemical and Biological Engineering on the ozonation of methotrexate (MTX) in water. Ozonation is the core treatment technology used in the Ozonator Industries NG-3000 solution in treating bio-hazardous waste. It was found that “MTX was totally degraded ...
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Jane S. Vergnes, Ph.D., DABT joins Bergeson & Campbell, P.C. and The Acta Group
Bergeson & Campbell, P.C. (B&C) is pleased to announce that Jane S. Vergnes, Ph.D., DABT has joined our team as Senior Toxicologist for B&C and The Acta Group (Acta). Dr. Vergnes has demonstrated outstanding leadership and an agile, multi-disciplinary talent for problem-solving in her 25 years directing global product stewardship and toxicology departments for Ashland, Inc., ...
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Jane S. Vergnes, Ph.D., DABT® Joins Bergeson & Campbell, P.C. and The Acta Group
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By Acta Group
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Safety first for pesticides
The Environment Committee voted on Wednesday on new legislation governing the production, licensing and use of pesticides. MEPs confirmed that certain toxic chemicals will be banned, except where there is a serious danger to plant health. They also argued that the EU should not be divided into three pesticide licensing zones. In addition, Member States will have to meet quantitative targets for ...
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EPA releases alternatives analysis for thermal paper, flame retardant chemicals
The Environmental Protection Agency has released two alternatives assessments to help companies that want to choose chemicals to substitute for bisphenol A in thermal paper and decabromodiphenyl ether (decaBDE) as a fire retardant for plastic. The goal of both analyses is to provide information about potential health and environmental hazards the chemicals and possible substitutes pose, the ...
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Positive feedback from the JEMS 39th Annual Meeting
Perceptive Instruments completed a successful trip to Japan last month, exhibiting at the 39th Annual Meeting of the Japanese Environmental Mutagen Society (JEMS). During the meeting we met many of our Japanese Comet Assay IV users, the majority of whom are active participants of the Japanese Center for the Validation of Alternative Methods (JaCVAM) ...
By Instem Group
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DTSC releases revised `Informal Draft` safer consumer products regulations
On October 31, 2011, the California Department of Toxic Substances Control (DTSC) released an "informal draft" Safer Consumer Products Regulations (SCPR). DTSC proposed these regulations after ten months of meetings following the California Secretary for Environmental Protection's instructions to DTSC to stop working on issuing proposed regulations and instead "take additional time to be ...
By Acta Group
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The 2012 LIFE+ projects
Austria 4 projects (14.5 million) LIFE+ Environment Policy and Governance (1 project – 3.6 million) LIFE-URBANLAKE (Stadt Wien – Magistratsabteilung 45 – Wiener Gewässer): This project intends to define strategies to reduce the vulnerability of the “Alte Donau” from effects of climate change and other anthropogenic pressures with the goal of securing the oxbow ...
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