titrator method News
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Quality control of disinfectants
Frequent handwashing using water and soap and stringent use of disinfectants are fundamental in the ongoing fight to curb the spreading of the Corona virus. Our latest Application Notes describe titration methods for manufacturers of disinfectants to determine the concentration of key components in their product applying titration methods. Hydrogen peroxide content as per ASTM D2180 ...
By Metrohm AG
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White Paper gives guidance for validation of titration methods
Using validated methods is a must for pharmaceutical assay determination to comply with regulatory requirements. A free white paper gives guidance and defines a procedure how to perform a proper validation of titration methods. The procedure follows ICH Guidance Q2(R1) and USP General Chapter and is exemplified using the determination of potassium bicarbonate sample as an example. Method ...
By Metrohm AG
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More convenient and more reliable: USP recommends new ion chromatography method for zinc oxide assay
USP has updated the General Chapter <591> «Zinc Determination» monograph to include ion chromatography as the preferred method for measuring zinc oxide. USP 41–NF 36 was developed in partnership with Metrohm and replaces manual titration methods. The new method is approved by the FDA and benefits users with more ease of use and reliability. Zinc oxide is used in ...
By Metrohm AG
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More Convenient and More Reliable: USP Recommends New Ion Chromatography Method for Zinc Oxide Assay
USP has updated the General Chapter«Zinc Determination» monograph to include ion chromatography as the preferred method for measuring zinc oxide. USP 41–NF 36 was developed in partnership with Metrohm and replaces manual titration methods. The new method is approved by the FDA and benefits users with more ease of use and reliability. Zinc oxide is used in various skin care ...
By Metrohm AG
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ASTM D8045 – New method for acid number determination in crude oil
Metrohm is pleased to announce that the ASTM has published method D8045 for the determination of Acid Number (AN) in crude oil and petroleum products. The new method describes thermometric titration and was developed by Metrohm together with industry leaders using the 859 Titrotherm titrator. Method D8045 demonstrates the superiority of thermometric titration for complex petroleum ...
By Metrohm AG
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tiamo™ – the No 1 titration software even more powerful now
Metrohm presents tiamo™ 2.2, the latest version of the leading software for titration and more. As a new feature, tiamo™ 2.2 now enables control of thermometric titrations. Moreover, new commands have been implemented to increase efficiency of your Metrohm instruments in the lab. The new graphical editor allows users to get more out of their titration system. New methods can be drawn ...
By Metrohm AG
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How to convert from manual to automated titration procedures
Titration is an important analytical method that is widely used for pharmaceutical assay testing. However, even though such tests are nowadays mostly performed utilizing digital instrumentation and software, USP general chapter still refers to manual visual endpoint titration. Recently, also US Pharmacopoeia has published recommendations for converting manual titrations into automated ...
By Metrohm AG
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Better reproducibility of results, compliance with GxP, and more
Many laboratories are still using manual titration to perform their routine analysis. However, glass burets are delicate to handle, volumes are difficult to read, and exposure to hazardous liquids pose a threat to the user’s health. A short video describes and explains these and other reasons why laboratories should switch from manual titration to using an automatic system with a ...
By Metrohm AG
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Karl Fischer titration - A step-by-step guide to correct results
Volumetric Karl Fischer Titration is a standard analytical method that is applied in many laboratories around the world for precise and fast water determination. However, its precision strongly depends on the correct procedure. In a free webinar on November 22, 2022, participants can learn the most important steps to consider in order to produce accurate, precise, and reproducible results for ...
By Metrohm AG
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Modernizing pharmaceutical assay testing
Titration is an important analytical method that is widely used for pharmaceutical assay testing. However, many USP monographs still refer to manual visual endpoint titration methods. Such manual procedures are not only tedious to perform but also more prone to human error. A free white paper by Metrohm summarizes the steps involved converting an existing manual titration procedure to ...
By Metrohm AG
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USP Monograph Modernization: Chemical Medicines Assay by Potentiometric Titration
USP and Metrohm jointly developed a potentiometric titration method for potassium bicarbonate and potassium carbonate assay. The new method uses autotitration combined with suitable equivalence point detection fulfilling all USP method validation requirements as per USP General Chapter <1225>. Many of the chemical medicine assay procedures are done by manual titration as per USP ...
By Metrohm AG
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Substituting Chromium – Thermometric Titration Method to Streamline Monitoring of Anodizing Baths
One of the biggest players from the aerospace industry has replaced chromium in their anodizing process of aircraft parts by a mix of sulfuric and tartaric acid (TSA, Tartaric Sulfuric Anodizing). Metrohm developed a new method allowing this customer to determine both acids quickly and reliably using the same sensor, a highly sensitive, fast responding thermometer. An Application Note ...
By Metrohm AG
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USP monograph modernization: Chemical medicines assay by potentiometric titration
USP and Metrohm jointly developed a potentiometric titration method for potassium bicarbonate and potassium carbonate assay. The new method uses autotitration combined with suitable equivalence point detection fulfilling all USP method validation requirements as per USP General Chapter <1225>. Many of the chemical medicine assay procedures are done by manual titration as per USP ...
By Metrohm AG
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New, modular system for multi-method analysis on a single platform
Quality control in many industries depends on the routine analysis of a handful of key parameters. Often, determination of these parameters is distributed across several technologies and methods. This goes along with cumbersome aggregation of results and management of data from different sources. With the launch of the new, modular OMNIS platform for comprehensive wet chemical analysis, ...
By Metrohm AG
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862 Compact Titrosampler – Unique in size and performance
Metrohm has launched the 862 Compact Titrosampler. This new instrument combines an autosampler and a titrator on the footprint of a typical analytical balance. The 862 has been designed to become the new benchmark in automated routine analysis. Forget lengthy system configuration and hours of user training. Plug-and-play functionality, predefined titration methods and straightforward operation ...
By Metrohm AG
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Eco Dosimat – new, universal tool boosts productivity in the laboratory
A great deal of time is spent in laboratories every day on repetitive routine task such as preparing standard solutions, controlling syntheses and/or performing manual titrations. With the new Eco Dosimat, much of this time can be saved, as these tasks are performed faster, easier, and much more reliably. The Eco Dosimat combines a digital buret, an integral magnetic stirrer, a touch ...
By Metrohm AG
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Quality control of NPK fertilizers - Rapid and reliable analysis by thermometric titration
Metrohm is pleased to present several titrimetric applications for the fast and straightforward determination of macronutrients such as sulfate, ammonium, potassium, and phosphate in NPK fertilizers. The reaction endpoint is determined using a thermometric sensor. Unlike competing methods such as gravimetric analysis or flame photometry, thermometric titration usually requires no sample ...
By Metrohm AG
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Eco Dosimat – New, Universal Tool Boosts Productivity in the Laboratory
A great deal of time is spent in laboratories every day on repetitive routine task such as preparing standard solutions, controlling syntheses and/or performing manual titrations. With the new Eco Dosimat, much of this time can be saved, as these tasks are performed faster, easier, and much more reliably. The Eco Dosimat combines a digital buret, an integral magnetic stirrer, a touch ...
By Metrohm AG
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Automated thermometric titrimetry – straightforward quality control of fats and oils
Minimum operator involvement and high analytical productivity – these are key benefits of automated thermometric titration. The method is ideal for monitoring the quality of fats and oils, namely to determine crucial parameters such as free fatty acid content and iodine value. Benefits of thermometric titrimetry Thermometric titration means that there is no electrical contact with ...
By Metrohm AG
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ASTM D3622 - 11 standard specification for 1-propanol (n-Propyl Alcohol)
This specification covers n-propyl alcohol (1-propanol) volatile solvents for use in paints, varnishes, lacquers, and related products. The solvents should conform to the specified requirements for apparent specific gravity, color, distillation range, nonvolatile matter content, odor, water content, and acidity. This abstract is a brief summary of the ...
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