Mettler - Toledo Int. Inc

METTLER TOLEDO Produces Hints and Tips Guide on Improving DO and pH Measurement Accuracy


Source: Mettler - Toledo Int. Inc

To achieve high quality products in pharmaceutical manufacturing, production processes must be stable, predictable and operate consistently at the target level of performance. This demands continuously reliable dissolved oxygen and pH measurements.

Urdorf, Switzerland -- Process analytics using in-line sensors plays a major role in monitoring manufacturing to ensure the required process conditions are always being met. Obviously, reliability of the data from sensors correlates with sensor measurement accuracy, but accuracy is not solely dependent on the use of high quality sensors.

Sensor maintenance and calibration procedures significantly influence a probe’s ability to measure dependably. pH and DO sensors have a certain accuracy associated with them as provided by the manufacturer. This accuracy can only be maintained if sensors are regularly and correctly calibrated. Further, calibration is essential in ensuring compliance with regulations such as global pharmacopeia.

METTLER TOLEDO's new guide, 'Hints and Tips to Improve Accuracy in DO and pH Measurement' covers good operating procedures for in-line pH and DO sensors and includes advice for sensor maintenance to ensure high measurement reliability at all times.

The guide also explains the advantages of digital sensors in comparison to analog probes and how they provide greater measurement accuracy.

The guide is available at

METTLER TOLEDO's Process Analytics division develops and manufactures instrumentation and sensors used for process measurement and control, offering measurements of pH, dissolved and gaseous oxygen, dissolved ozone, turbidity, oxygen reduction potential, resistivity/conductivity, total organic carbon and flow. METTLER TOLEDO Process Analytics consists of two business units, Ingold and Thornton, whose products are commonly used in industries such as:

  • Pharmaceuticals and biotechnology
  • Chemical process and refining industries
  • Brewing, food and beverage production
  • Power and steam generation plants
  • Microelectronics manufacturing

For additional information, visit

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